Mangiferin promotes porcine oocyte maturation and delays the postovulatory aging process by up-regulating NRF2 levels

Theriogenology, Journal Year: 2025, Volume and Issue: 239, P. 117384 - 117384

Published: March 10, 2025

Language: Английский

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Follicular oocyte as a potential target for severe acute respiratory syndrome coronavirus 2 infection

Reviews in Medical Virology, Journal Year: 2024, Volume and Issue: 34(4)

Published: June 27, 2024

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in December 2019 and rapidly became a pandemic as disease (COVID-19). Apart from other organs, presence of specific receptor angiotensin-converting enzyme (ACE2) corresponding proteases such transmembrane serine protease 2, basigin cysteine cathepsin L make follicular somatic cells well oocyte potential targets for SARS-CoV-2 infection. The causes inflammation hypoxia that generate reactive oxygen species (ROS) critically ill patients. In addition, large number casualties insecurity life due to repeated waves infection psychological stress cortisol resulting the further generation ROS. excess levels ROS under physiological range cause meiotic instability, while high result oxidative trigger various death pathways affect quality oocytes. Although, emerging evidence suggests utilises cellular machinery ovarian cells, generates impairs oocytes, underlying mechanism viral entry into host cell its negative impact on remains poorly understood. Therefore, this review summarises follicles oocytes functions stressed women.

Language: Английский

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Supplementation with L-kynurenine during in vitro maturation improves bovine oocytes developmental competence through its antioxidative action

Theriogenology, Journal Year: 2024, Volume and Issue: 233, P. 53 - 63

Published: Nov. 20, 2024

Language: Английский

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Damage mechanisms of bisphenols on the quality of mammalian oocytes

Human Reproduction, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 20, 2024

Abstract The extensive use of bisphenols in the plastics industry globally is a major growing concern for human health. Bisphenol compounds are easily leached out from plastic containers to food, beverages, and drinking water contaminate natural environment. Daily exposure bisphenol increases their load impairs various organs, including reproductive system. directly or indirectly affect ovarian functions, such as folliculogenesis, steroidogenesis, oogenesis, thereby oocyte quality. A (BPA) its structural analogues act endocrine disruptors induce generation reactive oxygen species (ROS) within ovary. Excess levels ROS death pathways follicular steroidogenic cells steroidogenesis. reduced level estradiol-17β growth development that reduces number quality oocytes. In addition, excess fluid trigger meiotic instability, which further deteriorates high generates oxidative stress triggers germ well oocytes, induces atresia, depletes reserve. Although evidence indicates destructive effects at ovary, potential underlying mechanisms deteriorate remain poorly understood. Therefore, this review summarizes by cause damage impair quality, women's fertility.

Language: Английский

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Female-age-dependent changes in the lipid fingerprint of the mammalian oocytes

Human Reproduction, Journal Year: 2024, Volume and Issue: 39(12), P. 2754 - 2767

Published: Oct. 4, 2024

Can oocyte functionality be assessed by observing changes in their intracytoplasmic lipid droplets (LDs) profiles?

Language: Английский

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Mangiferin Promotes Porcine Oocyte Maturation and Delays the Postovulatory Aging Process by Up-Regulating Nrf2 Levels

Published: Jan. 1, 2024

Language: Английский

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