Materials Chemistry and Physics, Journal Year: 2023, Volume and Issue: 297, P. 127340 - 127340
Published: Jan. 4, 2023
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 218, P. 930 - 968
Published: July 24, 2022
Language: Английский
Citations
266
Ceramics International, Journal Year: 2022, Volume and Issue: 48(11), P. 14959 - 14979
Published: March 12, 2022
Language: Английский
Citations
101
Materials Today Bio, Journal Year: 2023, Volume and Issue: 23, P. 100823 - 100823
Published: Oct. 1, 2023
Wound care and treatment can be critical from a clinical standpoint. While different strategies for the management of skin wounds have been developed, limitations inherent in current approaches necessitate development more effective alternative strategies. Advances tissue engineering resulted novel promising accelerating wound healing. The use various biomaterials capable regeneration damaged is engineering. In this regard, cerium oxide nanoparticles (CeO
Language: Английский
Citations
89
Macromol—A Journal of Macromolecular Research, Journal Year: 2023, Volume and Issue: 3(3), P. 524 - 553
Published: Aug. 3, 2023
Tissue engineering and regenerative medicine have emerged as innovative approaches to enhance clinical outcomes by addressing tissue lesions degenerations that can significantly impair organ function. Since human tissues limited capacity, the field of aims restore damaged their functionalities. Recent decades witnessed remarkable progress in materials science, engineering, medicine, leading development engineering. This interdisciplinary has revolutionized production artificial matrices, enabling design anatomically accurate structures with enhanced biocompatibility, bioabsorption, cell adhesion. Among techniques utilized for fabricating cellular scaffolds, electrospinning fibers stands out an ideal approach due its ability mimic characteristics extracellular matrix (ECM). Electrospun scaffolds exhibit distinct advantages, including a high surface area-to-volume ratio, exceptional porosity, uniformity, compositional diversity, structural flexibility, ease functionalization bioactive molecules controlled release. These versatile properties allow creation nanofiber closely resemble architecture ECM. Consequently, they facilitate transport nutrients oxygen cells well incorporation growth factors stimulate growth. advancements open up wide range applications medicine.
Language: Английский
Citations
82
Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(3), P. 1167 - 1315
Published: Jan. 1, 2024
Silicon-based biomaterials have been extensively developed in the past decades. The classification, characteristics, multi-dimensional design, and biomedical applications of silicon-containing are comprehensively elaborated.
Language: Английский
Citations
31
Journal of Biomaterials Science Polymer Edition, Journal Year: 2024, Volume and Issue: 35(6), P. 916 - 965
Published: Feb. 13, 2024
In tissue engineering and regenerative medicine applications, the utilization of bioactive materials has become a routine tool. The goal is to create new organs tissues by combining cell biology, science, reactor engineering, clinical research. As part growth pattern for primary cells in an organ, backing material frequently used as supporting material. A porous three-dimensional (3D) scaffold can provide with optimal conditions proliferating, migrating, differentiating, functioning framework. Optimizing scaffolds' structure altering their surface may improve adhesion proliferation. keratin-based biomaterials platform been developed result discoveries made over past century extraction, purification, characterization keratin proteins from hair wool fibers. Biocompatibility, biodegradability, intrinsic biological activity, cellular binding motifs make attractive biomaterial scaffolds. Scaffolds have extracted because capacity self-assemble polymerize into intricate 3D structures. this review article, applications scaffolds different including bone, skin, nerve, vascular are explained based on common methods fabrication such electrospinning, freeze-drying process, sponge replication method.
Language: Английский
Citations
16
International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 230, P. 123167 - 123167
Published: Jan. 5, 2023
Language: Английский
Citations
39
Materials, Journal Year: 2023, Volume and Issue: 16(12), P. 4267 - 4267
Published: June 8, 2023
This article provides a thorough overview of the available resorbable biomaterials appropriate for producing replacements damaged tissues. In addition, their various properties and application possibilities are discussed as well. Biomaterials fundamental components in tissue engineering (TE) scaffolds play critical role. They need to exhibit biocompatibility, bioactivity, biodegradability, non-toxicity, ensure ability function effectively with an host response. With ongoing research advancements medical implants, objective this review is explore recently developed implantable scaffold materials The categorization paper includes fossil-based (e.g., PCL, PVA, PU, PEG, PPF), natural or bio-based HA, PLA, PHB, PHBV, chitosan, fibrin, collagen, starch, hydrogels), hybrid PCL/PLA, PCL/PEG, PLA/PEG, PLA/PHB PCL/collagen, PCL/chitosan, PCL/starch, PLA/bioceramics). these both hard soft TE considered, particular focus on physicochemical, mechanical, biological properties. Furthermore, interactions between immune system context scaffold-driven regeneration discussed. Additionally, briefly mentions concept situ TE, which leverages self-renewal capacities affected tissues highlights crucial role played by biopolymer-based strategy.
Language: Английский
Citations
38
International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 233, P. 123651 - 123651
Published: Feb. 10, 2023
Language: Английский
Citations
32
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(7), P. 3836 - 3836
Published: March 29, 2024
Presently, millions worldwide suffer from degenerative and inflammatory bone joint issues, comprising roughly half of chronic ailments in those over 50, leading to prolonged discomfort physical limitations. These conditions become more prevalent with age lifestyle factors, escalating due the growing elderly populace. Addressing these challenges often entails surgical interventions utilizing implants or grafts, though treatments may entail complications such as pain tissue death at donor sites for along immune rejection. To surmount challenges, engineering has emerged a promising avenue injury repair reconstruction. It involves use different biomaterials development three-dimensional porous matrices scaffolds, alongside osteoprogenitor cells growth factors stimulate natural regeneration. This review compiles methodologies that can be used develop are important replacement Biomaterials orthopedic implants, several scaffold types production methods, well techniques assess biomaterials’ suitability human use—both laboratory settings within living organisms—are discussed. Even researchers have had some success, there is still room improvements their processing techniques, especially ones make scaffolds mechanically stronger without weakening biological characteristics. Bone therefore area rise bone-related injuries.
Language: Английский
Citations
15