Chitosan/MWCNTs nanocomposite coating on 3D printed scaffold of poly 3-hydroxybutyrate/magnetic mesoporous bioactive glass: A new approach for bone regeneration

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 260, P. 129407 - 129407

Published: Jan. 21, 2024

Language: Английский

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Chondrogenesis of mesenchymal stromal cells on the 3D printed polycaprolactone/fibrin/decellular cartilage matrix hybrid scaffolds in the presence of piascledine

Journal of Biomaterials Science Polymer Edition, Journal Year: 2024, Volume and Issue: 35(6), P. 799 - 822

Published: Jan. 30, 2024

Nowadays, cartilage tissue engineering (CTE) is considered important due to lack of repair cartilaginous lesions and the absence appropriate methods for treatment. In this study, polycaprolactone (PCL) scaffolds were fabricated by three-dimensional (3D) printing then coated with fibrin (F) acellular solubilized extracellular matrix (ECM). After extracting adipose-derived stem cells (ADSCs), 3D-printed characterized compared hydrogel groups. inducing chondrogenic differentiation in presence Piascledine comparing it TGF-β3 28 days, expression genes involved chondrogenesis (AGG, COLII) hypertrophic gene (COLX) examined real-time PCR. The proteins COLII COLX was also determined immunohistochemistry. Glycosaminoglycan measured toluidine blue staining. clearly improved cell proliferation, viability, water absorption compressive strength Moreover, use compounds such as ECM process ADSCs induction increased cartilage-specific markers decreased marker TGF-β3. groups, COLL II protein, Aggrecan genes, amount glycosaminoglycan showed a significant increase PCL/F/ECM PCL PCL/F

Language: Английский

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Novel biological synthesis and characterization of hydroxyapatite from Bos taurus, Gallus domesticus, and Ayam Cemaniosseous for orthopedic and dental applications

Biomass and Bioenergy, Journal Year: 2025, Volume and Issue: 194, P. 107618 - 107618

Published: Jan. 19, 2025

Language: Английский

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UiO-66 Metal-organic Framework (MOF) as an Osteogenic Stimulant in the Poly-3-hydroxybutyrate-zein/UiO-66 Electrospun Composite Scaffold for Bone Tissue Engineering Applications

Journal of Polymers and the Environment, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 15, 2025

Language: Английский

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Inorganic Nanoparticles in Bone Healing Applications

Pharmaceutics, Journal Year: 2022, Volume and Issue: 14(4), P. 770 - 770

Published: March 31, 2022

Modern biomedicine aims to develop integrated solutions that use medical, biotechnological, materials science, and engineering concepts create functional alternatives for the specific, selective, accurate management of medical conditions. In particular case tissue engineering, designing a model simulates all qualities fulfills requirements is continuous challenge in field bone regeneration. The therapeutic protocols used healing applications are limited by hierarchical nature extensive vascularization osseous tissue, especially large lesions. this regard, nanotechnology paves way new era treatment, repair regeneration, enabling fabrication complex nanostructures similar those found natural which exhibit multifunctional bioactivity. This review lay out tremendous outcomes using inorganic nanoparticles applications, including modern strategies bone-related pathologies.

Language: Английский

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Effect of cellulose nanofibers on polyhydroxybutyrate electrospun scaffold for bone tissue engineering applications

International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 220, P. 1402 - 1414

Published: Sept. 16, 2022

Language: Английский

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Fabrication and characterization of novel polyhydroxybutyrate-keratin/nanohydroxyapatite electrospun fibers for bone tissue engineering applications

International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 220, P. 1368 - 1389

Published: Sept. 15, 2022

Language: Английский

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Electrospun halloysite nanotube loaded polyhydroxybutyrate-starch fibers for cartilage tissue engineering

International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 214, P. 301 - 311

Published: June 15, 2022

Language: Английский

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Electrospinning Inorganic Nanomaterials to Fabricate Bionanocomposites for Soft and Hard Tissue Repair

Nanomaterials, Journal Year: 2023, Volume and Issue: 13(1), P. 204 - 204

Published: Jan. 2, 2023

Tissue engineering (TE) has attracted the widespread attention of research community as a method producing patient-specific tissue constructs for repair and replacement injured tissues. To date, different types scaffold materials have been developed various tissues organs. The choice material should take into consideration whether mechanical properties, biodegradability, biocompatibility, bioresorbability meet physiological properties Owing to their broad range physico-chemical inorganic can induce series biological responses fillers, which render them good alternative (TE). While it is worth further explore mechanistic insight use nanomaterials repair, in this review, we mainly focused on utilization forms strategies fabricating electrospun membranes containing components based electrospinning technology. A particular emphasis placed advantages incorporating along with organic constituents repair. As well widely exploited natural synthetic polymers, offer an enticing platform modulate composite scaffolds, may help broaden application prospect scaffolds TE.

Language: Английский

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GelMA/TCP nanocomposite scaffold for vital pulp therapy

Acta Biomaterialia, Journal Year: 2023, Volume and Issue: 173, P. 495 - 508

Published: Nov. 7, 2023

Language: Английский

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