Polymer Engineering and Science,
Journal Year:
2024,
Volume and Issue:
64(11), P. 5831 - 5841
Published: Sept. 24, 2024
Abstract
Calcium
phosphate
hydroxyapatite
(HA)
was
successfully
incorporated
into
poly(3‐hydroxybutyrate‐co‐3‐hydroxyvalerate)/gelatin
(PHBV/GEL)
nanofibers
through
an
electrospinning
process
in
a
hexafluoroisopropanol
solvent
(HFIP).
The
PHBV/GEL
electrospun
and
collected
using
rotating
metallic
network
to
develop
highly
ordered
nonwoven
mats.
effects
of
HA
addition
on
the
morphologies
obtained
fibers
were
investigated
SEM.
average
diameter
ranged
around
700–900
nm,
depending
content.
From
mechanical
perspective,
nanoparticles
showed
variations
tensile
strength
elastic
modulus
values.
lowest
measured
for
neat
0.37
±
0.08
MPa
with
9.45
0.65
MPa,
whereas
highest
reported
5%
HA‐loaded
mats
1.1
0.4
16.9
0.39
MPa.
In
addition,
cell
viability,
mineral
deposition
also
studied
MC3T3‐E1
pre‐osteoblasts.
vitro
experiment
results
that
loaded‐PHBV/GEL
provide
optimal
conditions
growth
osteogenic
differentiation
cells.
This
study
reveals
potential
PHBV/GEL/HA
matrices
development
novel
guided
bone‐regeneration
(GBR)
membranes
orthopedic
craniomaxillofacial
surgery,
by
providing
favorable
structural
features
attachment,
growth,
osteoblast
Highlights
Simple
cheap
strategy
toward
network‐like
fibrous
Microstructure,
mechanical,
biological
evaluated.
Electrospun
promoted
calcium
Nanomaterials,
Journal Year:
2024,
Volume and Issue:
14(7), P. 646 - 646
Published: April 8, 2024
Dressings
with
multiple
functional
performances
(such
as
hemostasis,
promoting
regeneration,
analgesia,
and
anti-inflammatory
effects)
are
highly
desired
in
orthopedic
surgery.
Herein,
several
new
kinds
of
medicated
nanofibers
loaded
active
ingredients
for
providing
functions
were
prepared
using
the
modified
coaxial
electrospinning
processes.
With
an
electrospinnable
solution
composed
polycaprolactone
fenoprofen
core
working
fluid,
different
types
unspinnable
fluids
(including
pure
solvent,
nanosuspension
containing
tranexamic
acid
hydroxyapatite,
dilute
polymeric
comprising
acid,
polyvinylpyrrolidone)
explored
to
implement
processes
creating
multifunctional
nanofibers.
Their
morphologies
inner
structures
assessed
through
scanning
transmission
electron
microscopes,
which
all
showed
a
linear
format
without
discerned
beads
or
spindles
diameter
smaller
than
1.0
μm,
some
them
had
incomplete
core–shell
nanostructures,
represented
by
symbol
@.
Additionally,
strange
details
about
sheaths’
topographies
observed,
included
cracks,
adhesions,
embedded
nanoparticles.
XRD
FTIR
verified
that
drugs
presented
amorphous
state,
resulted
from
fine
compatibility
among
involved
components.
All
samples
demonstrated
have
hydrophilic
property
exhibited
lower
water
contact
angle
40°
300
ms.
In
vitro
dissolution
tests
indicated
was
released
sustained
manner
over
6
h
typical
Fickian
diffusion
mechanism.
Hemostatic
intentional
distribution
on
shell
sections
able
endow
rapid
hemostatic
effect
within
60
s.
Polymers,
Journal Year:
2023,
Volume and Issue:
15(21), P. 4243 - 4243
Published: Oct. 27, 2023
Food
waste
is
a
pressing
global
challenge
leading
to
over
$1
trillion
lost
annually
and
contributing
up
10%
of
greenhouse
gas
emissions.
Extensive
study
has
been
directed
toward
the
use
active
biodegradable
packaging
materials
improve
food
quality,
minimize
plastic
use,
encourage
sustainable
technology
development.
However,
this
achieved
with
limited
success,
which
can
mainly
be
attributed
poor
material
properties
high
production
costs.
In
recent
literature,
integration
silver
nanoparticles
(AgNPs)
shown
biopolymer,
prompting
development
bionanocomposites.
Furthermore,
antibacterial
AgNPs
against
foodborne
pathogens
leads
towards
shelf-life
improvement
provides
route
reducing
waste.
few
reviews
have
analyzed
holistically
throughout
portfolio
biopolymers
from
an
industrial
perspective.
Hence,
review
critically
analyses
antibacterial,
barrier,
mechanical,
thermal,
water
resistance
AgNP-based
These
advanced
are
also
discussed
in
terms
applications
assessed
their
performance
enhancing
shelf-life.
Finally,
current
barriers
commercialization
AgNP
bionanocomposites
provide
action
plan
reduce
Frontiers in Bioengineering and Biotechnology,
Journal Year:
2023,
Volume and Issue:
11
Published: April 6, 2023
As
an
interdisciplinary
field,
drug
delivery
relies
on
the
developments
of
modern
science
and
technology.
Correspondingly,
how
to
upgrade
traditional
dosage
forms
for
a
more
efficacious,
safer,
convenient
poses
continuous
challenge
researchers.
Journal of the Textile Institute,
Journal Year:
2024,
Volume and Issue:
unknown, P. 1 - 19
Published: April 18, 2024
Antimicrobial
products
are
in
high
demand
due
to
the
sudden
outbreak
of
Sars-Cov-2.
For
a
long
time,
bacterial
infections
have
posed
great
threat
human
lives.
The
new
emerging
technology
address
this
alarming
situation
is
using
nanofibers
with
antibacterial
properties.
Nanofibers
large
surface
area
that
supports
effective
incorporation
agents.
Several
biocides
been
incorporated
by
different
techniques
into
show
strong
activity.
Due
their
morphology,
porosity,
and
flexibility,
nanofibrous
structures
being
used
variety
applications,
including
wound
dressing,
tissue
scaffolds,
biomedical
devices.
This
review
summarizes
manufacturing
process
applications
medicine
antimicrobial
capability.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(13), P. 11037 - 11037
Published: July 3, 2023
Injuries
and
diseases
of
the
skin
require
accurate
treatment
using
nontoxic
noninvasive
biomaterials,
which
aim
to
mimic
natural
structures
body.
There
is
a
strong
need
develop
biodevices
capable
accommodating
nutrients
bioactive
molecules
generating
process
vascularization.
Electrospinning
robust
technique,
as
it
can
form
fibrous
for
tissue
engineering
wound
dressings.
The
best
way
forming
such
meshes
healing
choose
two
polymers
that
complement
each
other
regarding
their
properties.
On
one
hand,
PVA
water-soluble
synthetic
polymer
widely
used
preparation
hydrogels
in
field
biomedicine
owing
its
biocompatibility,
water
solubility,
nontoxicity,
considerable
mechanical
easy
subject
electrospinning
offer
stability
mesh,
but
necessary
improve
biological
CS
has
good
properties,
including
biodegradability,
antimicrobial
Still,
harder
electrospin
does
not
possess
properties
PVA.
As
these
also
allow
incorporation
agents
due
high
surface-area-to-volume
ratio,
interesting
point
was
incorporate
usnic
acid
into
structure
suitable
alternative
agent
burn
wounds
avoids
an
improper
or
overuse
antibiotics
invasive
biomolecules.
Thus,
we
report
fabrication
electrospun
nanofibrous
mesh
based
on
PVA,
chitosan,
with
applications
healing.
obtained
nanofibers
physicochemically
characterized
by
Fourier
transform
infrared
spectroscopy
(FT-IR)
scanning
electron
microscopy
(SEM).
In
vitro
assays
were
performed
evaluate
samples
MIC
(minimum
inhibitory
concentration)
assay
evaluating
influence
fabricated
Staphylococcus
aureus
biofilm
development,
well
biocompatibility
(demonstrated
fluorescence
results,
XTT
assay,
glutathione
(GSH)
assay).
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(6), P. 1728 - 1728
Published: June 14, 2023
The
production
of
highly
porous
and
three-dimensional
(3D)
scaffolds
with
biomimicking
abilities
has
gained
extensive
attention
in
recent
years
for
tissue
engineering
(TE)
applications.
Considering
the
attractive
versatile
biomedical
functionality
silica
(SiO2)
nanomaterials,
we
propose
herein
development
validation
SiO2-based
3D
TE.
This
is
first
report
on
fibrous
architectures,
using
tetraethyl
orthosilicate
(TEOS)
polyvinyl
alcohol
(PVA)
during
self-assembly
electrospinning
(ES)
processing
(a
layer
flat
fibers
must
be
created
before
fiber
stacks
can
develop
mat).
compositional
microstructural
characteristics
obtained
materials
were
evaluated
by
complementary
techniques,
both
pre-ES
aging
period
post-ES
calcination.
Then,
vivo
evaluation
confirmed
their
possible
use
as
bioactive
bone
