Enzyme-Friendly Solvent for One-Pot Chemobiocatalytic Valorization of Fructose into Valuable Furanics via 5-Hydroxymethylfurfural DOI
Qian Wu,

Min‐Hua Zong,

Ning Li

et al.

ACS Sustainable Chemistry & Engineering, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 22, 2024

Direct conversion of inexpensive fructose into value-added furanic chemicals via chemobiocatalytic cascades is a highly attractive yet challenging task due to the incompatibility issues between chemo- and biocatalysts. Among issues, solvent crucial make two worlds catalysts work well in one pot. In this work, we present an enzyme-friendly natural deep eutectic (NADES)-based medium for one-pot valorization valuable furanics 5-hydroxymethylfurfural (HMF). HMF was obtained with approximately 40% yield 64% selectivity within 1.5 h under 150 °C 15 wt % NADES (choline chloride/oxalic acid, 1:1, mol/mol) aqueous solution. significantly improved 91% by applying vol methyl isobutyl ketone/NADES biphasic medium. A NADES/unreacted recycle process designed improve both overall (77%) (72%). The NADES-based benign toward various biocatalysts such as alcohol aldehyde dehydrogenases, acyltransferase, ω-transaminase, evidenced good yields (86–97%) desired products subsequent biotransformations. Specifically, 2,5-bis(hydroxymethyl)furan from 41% isolated gram-scale synthesis. This may lay foundation sustainable manufacture high-value biomass.

Language: Английский

Identifying a robust alcohol dehydrogenase for developing one-pot chemobiocatalytic route toward 2,5-bis(hydroxymethyl)furan from glucose DOI
Qian Wu,

Min‐Hua Zong,

Ning Li

et al.

Molecular Catalysis, Journal Year: 2025, Volume and Issue: 573, P. 114813 - 114813

Published: Jan. 5, 2025

Language: Английский

Citations

0
Surface phosphorylation of macroporous pine wood for adsorptive remediation of uranium-contaminated water bodies DOI

Chuanlei Luo,

Xu Zhang, Hong Li

et al.

Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 136828 - 136828

Published: April 1, 2025

Language: Английский

Citations

0
Enzyme-Friendly Solvent for One-Pot Chemobiocatalytic Valorization of Fructose into Valuable Furanics via 5-Hydroxymethylfurfural DOI
Qian Wu,

Min‐Hua Zong,

Ning Li

et al.

ACS Sustainable Chemistry & Engineering, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 22, 2024

Direct conversion of inexpensive fructose into value-added furanic chemicals via chemobiocatalytic cascades is a highly attractive yet challenging task due to the incompatibility issues between chemo- and biocatalysts. Among issues, solvent crucial make two worlds catalysts work well in one pot. In this work, we present an enzyme-friendly natural deep eutectic (NADES)-based medium for one-pot valorization valuable furanics 5-hydroxymethylfurfural (HMF). HMF was obtained with approximately 40% yield 64% selectivity within 1.5 h under 150 °C 15 wt % NADES (choline chloride/oxalic acid, 1:1, mol/mol) aqueous solution. significantly improved 91% by applying vol methyl isobutyl ketone/NADES biphasic medium. A NADES/unreacted recycle process designed improve both overall (77%) (72%). The NADES-based benign toward various biocatalysts such as alcohol aldehyde dehydrogenases, acyltransferase, ω-transaminase, evidenced good yields (86–97%) desired products subsequent biotransformations. Specifically, 2,5-bis(hydroxymethyl)furan from 41% isolated gram-scale synthesis. This may lay foundation sustainable manufacture high-value biomass.

Language: Английский

Citations

3