Ecotoxicology and Environmental Safety,
Journal Year:
2021,
Volume and Issue:
224, P. 112698 - 112698
Published: Aug. 25, 2021
In
vivo
testing
systems
for
environmental
androgens
are
scarce.
The
aim
of
this
study
was
to
evaluate
the
potential
male-specific
brightened
body
coloration
in
female
guppies
(Poecilia
reticulata)
serve
as
an
biomarker
using
17β-trenbolone
example.
high
bioaccumulation
skin
suggests
that
it
is
a
target
tissue
androgens.
index,
pigment
cell
ultrastructure,
levels,
sexual
attractiveness,
and
reproductive
capability
were
analyzed
following
28
days
exposure
20
ng/L,
200
2000
ng/L
17β-trenbolone.
Increases
index
caused
by
attributable
increased
pteridine
melanin
levels.
Decreases
number
offspring,
survival
rate
offspring
suggested
changes
translated
into
adverse
outcomes.
Finally,
mRNA
sequencing
indicated
levels
activating
genomic
effects
androgen
receptor
on
xanthine
dehydrogenase
exerting
non-genomic
targeting
microphthalmia-associated
transcription
factor,
tyrosinase,
tyrosinase-related
protein
1
mediated
mitogen-activated
kinase
calcium
signaling
pathways.
We
have
derived
robust
outcome
pathway
androgens,
our
findings
suggest
indicators
at
different
biological
related
can
less-invasive
or
noninvasive
biomarkers
short-term
Philosophical Transactions of the Royal Society B Biological Sciences,
Journal Year:
2019,
Volume and Issue:
374(1781), P. 20180055 - 20180055
Published: July 29, 2019
Pollution
(e.g.
by
chemicals,
noise,
light,
heat)
is
an
insidious
consequence
of
anthropogenic
activity
that
affects
environments
worldwide.
Exposure
wildlife
to
pollutants
has
the
capacity
adversely
affect
animal
communication
and
behaviour
across
a
wide
range
sensory
modalities—by
not
only
impacting
signalling
environment,
but
also
way
in
which
animals
produce,
perceive
interpret
signals
cues.
Such
disturbances,
particularly
when
it
comes
sex,
can
drastically
alter
fitness.
Here,
we
consider
how
disrupt
during
mate
choice,
ecological
evolutionary
changes
such
disturbances
engender.
We
explain
different
stages
choice
be
affected
pollution,
from
encountering
mates
final
these
influence
individual
fitness,
population
dynamics
community
structure.
end
with
discussing
understanding
help
inform
better
conservation
management
practices
highlight
important
considerations
avenues
for
future
research.
This
article
part
theme
issue
‘Linking
populations
communities:
application
novel
approaches
behavioural
ecology
conservation’.
Environment International,
Journal Year:
2024,
Volume and Issue:
187, P. 108703 - 108703
Published: April 26, 2024
Poly-
and
perfluoroalkyl
substances
(PFAS)
are
frequently
detected
in
the
environment
linked
to
adverse
reproductive
health
outcomes
humans.
Although
legacy
PFAS
have
been
phased
out
due
their
toxicity,
alternative
increasingly
used
despite
fact
that
information
on
toxic
effects
traits
is
particularly
scarce.
Here,
we
exposed
male
guppies
(Poecilia
reticulata)
for
a
short
period
(21
days)
an
environmentally
realistic
concentration
(1
ppb)
of
PFOA,
PFAS,
its
replacement
compound,
GenX,
assess
impact
gene
expression.
Exposure
did
not
impair
survival
but
instead
caused
sublethal
effects.
Overall,
exposure
changes
sexual
behaviour
had
detrimental
sperm
motility.
Sublethal
variations
were
also
seen
at
transcriptional
level,
with
modulation
genes
involved
immune
regulation,
spermatogenesis,
oxidative
stress.
We
observed
bioaccumulation
which
was
higher
PFOA
than
GenX.
Our
results
offer
comprehensive
comparison
these
two
shed
light
toxicity
newly
emerging
PFAS.
It
therefore
evident
even
low
concentrations
exposure,
can
subtle
yet
significant
behaviour,
fertility,
immunity.
These
findings
underscore
potential
ramifications
pollution
under
natural
conditions
fish
populations.
Environmental Toxicology and Chemistry,
Journal Year:
2018,
Volume and Issue:
37(8), P. 2064 - 2078
Published: April 27, 2018
Trenbolone
acetate
is
widely
used
in
some
parts
of
the
world
for
its
desirable
anabolic
effects
on
livestock.
Several
metabolites
acetate,
including
17β-trenbolone,
have
been
detected
at
low
nanograms
per
liter
concentrations
surface
waters
associated
with
animal
feedlots.
The
17β-trenbolone
isomer
can
affect
androgen
receptor
signaling
pathways
various
vertebrate
species
comparatively
concentrations/doses.
present
article
provides
a
comprehensive
review
and
synthesis
existing
literature
concerning
exposure
to
biological
an
emphasis
potential
risks
aquatic
animals.
In
vitro
studies
indicate
that,
although
activate
several
nuclear
hormone
receptors,
highest
affinity
all
taxa
examined,
fish.
Exposure
fish
water
cause
changes
endocrine
function
short
term,
adverse
apical
longer
exposures
during
development
reproduction.
Impacts
typically
are
indicative
inappropriate
signaling,
such
as
sex
steroid
metabolism,
impacts
gonadal
stage,
masculinization
females.
sexual
differentiation
early
greatly
skew
ratios,
whereas
adult
adversely
impact
fertility
fecundity.
To
fully
assess
ecosystem-level
risks,
additional
research
warranted
address
uncertainties
degree/breadth
environmental
population-level
sensitive
species.
Environ
Toxicol
Chem
2018;37:2064-2078.
Published
2018
Wiley
Periodicals
Inc.
behalf
SETAC.
This
US
government
work
and,
such,
public
domain
United
States
America.
