Phytomedicine Plus,
Journal Year:
2022,
Volume and Issue:
3(1), P. 100396 - 100396
Published: Dec. 24, 2022
Medicinal
plants
and
their
highly
valuable
compounds
are
used
worldwide
as
therapeutic
interventions
for
the
management
of
complex,
multifactorial
physiologic
imbalances,
various
other
health
problems
including
cancer.
However,
characteristics
active
components
precise
mechanisms
underlying
beneficial
effects
medicinal
largely
unclear,
which
obstructs
progression
to
clinical
trials
ultimately
pharmacy.
This
integrative
review
presents
critical
synthesized
literature
on
anticancer
derivatives.
Databases
such
PubMed
Google
Dataset
were
searched
using
key
words
related
fields
botanical
derivatives
cancer
identify
articles
that
describe
properties
signal
transduction
pathways
Furthermore,
Clinical
Trial
database
was
find
drugs
derived
from
or
natural
sources.
Publications
this
search
gathered
based
relevance
summarized
results
significance.
Anticancer
ingredients
phenolic
compounds,
flavonoids
alkaloids
present
in
plants.
These
bioactive
modulate
proliferative
apoptotic
factors
prevent
tumor
growth.
Botanical
have
been
utilized
lead
development
new
drugs.
Several
chemotherapy
medicines
leads
approved
by
FDA.
The
impacted
pharmacological
application
integrated
summarized.
There
a
variety
plant-derived
with
property.
Signal
cascades
responsible
proliferation,
cell
cycle
arrest,
apoptosis,
angiogenesis
implicated
actions
It
is
expected
novel
therapeutics
can
be
developed
treat
patients
Sensors,
Journal Year:
2022,
Volume and Issue:
22(3), P. 1151 - 1151
Published: Feb. 2, 2022
A
very
simple,
as
well
sensitive
and
selective,
sensing
protocol
was
developed
on
a
pre-anodized
graphite
pencil
electrode
surface
coated
using
poly(thionine)
(APGE/PTH).
The
then
used
for
simultaneous
of
3-nitrophenol
(3-NP)
4-nitrophenol
(4-NP).
exhibited
an
enhanced
electrocatalytic
property
towards
nitrophenol
(3-NP
4-NP)
reduction.
Redox
peak
potential
current
both
nitrophenols
were
found
resolved
their
analysis
studied.
Under
optimized
experimental
conditions,
APGE/PTH
showed
long
linear
concentration
range
from
20
to
230
nM
15
280
with
calculated
limit
detection
(LOD)
4.5
4
sensitivity
22.45
µA/nM
27.12
3-NP
4-NP,
respectively.
Real
sample
the
prepared
sensor
tested
different
environmental
water
samples
sensors
excellent
recovery
results
in
98.16
103.43%.
Finally,
exposed
promising
selectivity,
stability,
reproducibility
4-NP.
Phytomedicine Plus,
Journal Year:
2022,
Volume and Issue:
3(1), P. 100396 - 100396
Published: Dec. 24, 2022
Medicinal
plants
and
their
highly
valuable
compounds
are
used
worldwide
as
therapeutic
interventions
for
the
management
of
complex,
multifactorial
physiologic
imbalances,
various
other
health
problems
including
cancer.
However,
characteristics
active
components
precise
mechanisms
underlying
beneficial
effects
medicinal
largely
unclear,
which
obstructs
progression
to
clinical
trials
ultimately
pharmacy.
This
integrative
review
presents
critical
synthesized
literature
on
anticancer
derivatives.
Databases
such
PubMed
Google
Dataset
were
searched
using
key
words
related
fields
botanical
derivatives
cancer
identify
articles
that
describe
properties
signal
transduction
pathways
Furthermore,
Clinical
Trial
database
was
find
drugs
derived
from
or
natural
sources.
Publications
this
search
gathered
based
relevance
summarized
results
significance.
Anticancer
ingredients
phenolic
compounds,
flavonoids
alkaloids
present
in
plants.
These
bioactive
modulate
proliferative
apoptotic
factors
prevent
tumor
growth.
Botanical
have
been
utilized
lead
development
new
drugs.
Several
chemotherapy
medicines
leads
approved
by
FDA.
The
impacted
pharmacological
application
integrated
summarized.
There
a
variety
plant-derived
with
property.
Signal
cascades
responsible
proliferation,
cell
cycle
arrest,
apoptosis,
angiogenesis
implicated
actions
It
is
expected
novel
therapeutics
can
be
developed
treat
patients
