Pharmaceutical pollution alters the cost of bacterial infection and its relationship to pathogen load DOI Open Access
Lucinda C. Aulsebrook, Bob B. M. Wong, Matthew D. Hall

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 23, 2023

Abstract The relationship between pathogen proliferation and the cost of infection experienced by a host drives ecology evolution host-pathogen dynamics. While environmental factors can shape this relationship, there is currently limited knowledge on consequences emerging contaminants, such as pharmaceutical pollutants, for commonly observed trade-off pathogen’s growth within damage it causes, termed its virulence. Here, we investigated how exposure to fluoxetine (Prozac), detected psychoactive pollutant, could alter key using water flea Daphnia magna bacterial Pasteuria ramosa model system. Across variety concentrations, found that shaped caused, reduction in fecundity or intrinsic infected individuals, but with minimal change average spore loads. Instead, modified degree virulence, both strength component fitness most affected varying concentration genotype. Our study underscores potential pollution modify virulence an invading pathogen, well fundamental fitness, even at trace amounts increasingly natural waterways.

Language: Английский

Time is of the essence: The importance of considering biological rhythms in an increasingly polluted world DOI Creative Commons
Eli S.J. Thoré, Anne E. Aulsebrook, Jack A. Brand

et al.

PLoS Biology, Journal Year: 2024, Volume and Issue: 22(1), P. e3002478 - e3002478

Published: Jan. 30, 2024

Biological rhythms have a crucial role in shaping the biology and ecology of organisms. Light pollution is known to disrupt these rhythms, evidence emerging that chemical pollutants can cause similar disruption. Conversely, biological influence effects toxicity chemicals. Thus, by drawing insights from extensive study biomedical light research, we greatly improve our understanding pollution. This Essay advocates for integration rhythmicity into research gain more comprehensive how affect wildlife ecosystems. Despite historical barriers, recent experimental technological advancements now facilitate ecotoxicology, offering unprecedented, high-resolution data across spatiotemporal scales. Recognizing importance will be essential understanding, predicting, mitigating complex ecological repercussions

Language: Английский

Citations

8
Long‐term effects of widespread pharmaceutical pollution on trade‐offs between behavioural, life‐history and reproductive traits in fish DOI Creative Commons
Upama Aich, Giovanni Polverino, Farin Yazdan Parast

et al.

Journal of Animal Ecology, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 26, 2024

Abstract In our rapidly changing world, understanding how species respond to shifting conditions is of paramount importance. Pharmaceutical pollutants are widespread in aquatic ecosystems globally, yet their impacts on animal behaviour, life‐history and reproductive allocation remain poorly understood, especially the context intraspecific variation ecologically important traits that facilitate species' adaptive capacities. We test whether a pharmaceutical pollutant, fluoxetine (Prozac), disrupts trade‐off between individual‐level (co)variation behavioural, freshwater fish. exposed progeny wild‐caught guppies ( Poecilia reticulata ) three field‐relevant levels (mean measured concentrations: 0, 31.5 316 ng/L) for 5 years, across multiple generations. used 12 independent laboratory populations repeatedly quantified activity risk‐taking behaviour male guppies, capturing both mean behaviours within individuals exposure treatments. also key (body condition, coloration gonopodium size) assessed post‐copulatory sperm (sperm vitality, number velocity) known be under strong sexual selection polyandrous species. Intraspecific these was analysed using comprehensive, multivariate statistical approach. Fluoxetine had dose‐specific (mean) effect trait guppies: low pollutant altered body condition increased size, but reduced velocity. At individual level, behavioural plasticity by eroding within‐individual behaviour. between‐individual correlations pace‐of‐life syndrome traits: it triggered emergence (e.g. condition) size vitality), collapsed other size). Our results reveal chronic global can affect phenotypic at population levels, even alter among such manner. discuss need integrate analyses association with fully understand animals human‐induced environmental change.

Language: Английский

Citations

6
Advancing the Spatiotemporal Dimension of Wildlife–Pollution Interactions DOI Creative Commons
Jack A. Brand, Jake M. Martin, Marcus Michelangeli

et al.

Environmental Science & Technology Letters, Journal Year: 2025, Volume and Issue: unknown

Published: March 18, 2025

Chemical pollution is one of the fastest-growing agents global change. Numerous pollutants are known to disrupt animal behavior, alter ecological interactions, and shift evolutionary trajectories. Crucially, both chemical individual organisms nonrandomly distributed throughout environment. Despite this fact, current evidence for chemical-induced impacts on wildlife largely stems from tests that restrict organism movement force homogeneous exposures. While such approaches have provided pivotal ecotoxicological insights, they overlook dynamic spatiotemporal interactions shape wildlife-pollution relationships in nature. Indeed, seemingly simple notion animals move environment creates a complex many which never been theoretically modeled or experimentally tested. Here, we conceptualize between variation highlight their implications. We propose three-pronged approach-integrating silico modeling, laboratory experiments allow movement, field-based tracking free-ranging animals-to bridge gap controlled studies real-world Advances telemetry, remote sensing, computational models provide necessary tools quantify these paving way new era ecotoxicology accounts complexity.

Language: Английский

Citations

0
Pharmaceutical Pollution Alters the Structure of Freshwater Communities and Hinders Their Recovery from a Fish Predator DOI Creative Commons
Marcus Michelangeli, Jake M. Martin,

Stephanie Victoria Robson

et al.

Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(31), P. 13904 - 13917

Published: July 25, 2024

Freshwater ecosystems are under threat from rising pharmaceutical pollution. While such pollutants known to elicit biological effects on organisms, we have limited knowledge how these might cascade through food-webs, disrupt ecological processes, and shape freshwater communities. In this study, used a mesocosm experiment explore the community impacts of top-order predator, eastern mosquitofish (

Language: Английский

Citations

2
Pharmaceutical pollution alters the cost of bacterial infection and its relationship to pathogen load DOI Creative Commons
Lucinda C. Aulsebrook, Bob B. M. Wong, Matthew D. Hall

et al.

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 291(2014)

Published: Jan. 10, 2024

The relationship between pathogen proliferation and the cost of infection experienced by a host drives ecology evolution host–pathogen dynamics. While environmental factors can shape this relationship, there is currently limited knowledge on consequences emerging contaminants, such as pharmaceutical pollutants, pathogen's growth within damage it causes, termed its virulence. Here, we investigated how exposure to fluoxetine (Prozac), commonly detected psychoactive pollutant, could alter key using water flea Daphnia magna bacterial Pasteuria ramosa model system. Across variety concentrations, found that shaped caused, reduction in fecundity or intrinsic infected individuals, but with minimal change average spore loads. Instead, modified degree virulence, both strength trade-off component fitness most affected varying concentration genotype. Our study underscores potential for pollution modify virulence an invading pathogen, well fundamental fitness, even at trace amounts increasingly natural waterways.

Language: Английский

Citations

1
Enantioselective disruption of circadian rhythm behavior in goldfish (Carassius auratus) induced by chiral fungicide triadimefon at environmentally-relevant concentration DOI

Linjia Liu,

Liuqingqing Liu,

Zixi Yuan

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 485, P. 136891 - 136891

Published: Dec. 15, 2024

Language: Английский

Citations

1
Various species of Basidiomycota fungi reveal different abilities to degrade pharmaceuticals and also different pathways of degradation DOI
Bartosz Kózka, Agata Sośnicka, Grzegorz Nałęcz‐Jawecki

et al.

Chemosphere, Journal Year: 2023, Volume and Issue: 338, P. 139481 - 139481

Published: July 14, 2023

Language: Английский

Citations

3
In-stream attenuation and enantioselective fractionation of psychiatric pharmaceuticals in a wastewater effluent-dominated river basin DOI
Weimin Wang, Tian Xie,

Ning Ma

et al.

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 951, P. 175521 - 175521

Published: Aug. 13, 2024

Language: Английский

Citations

0
Pharmaceutical pollution alters the cost of bacterial infection and its relationship to pathogen load DOI Open Access
Lucinda C. Aulsebrook, Bob B. M. Wong, Matthew D. Hall

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 23, 2023

Abstract The relationship between pathogen proliferation and the cost of infection experienced by a host drives ecology evolution host-pathogen dynamics. While environmental factors can shape this relationship, there is currently limited knowledge on consequences emerging contaminants, such as pharmaceutical pollutants, for commonly observed trade-off pathogen’s growth within damage it causes, termed its virulence. Here, we investigated how exposure to fluoxetine (Prozac), detected psychoactive pollutant, could alter key using water flea Daphnia magna bacterial Pasteuria ramosa model system. Across variety concentrations, found that shaped caused, reduction in fecundity or intrinsic infected individuals, but with minimal change average spore loads. Instead, modified degree virulence, both strength component fitness most affected varying concentration genotype. Our study underscores potential pollution modify virulence an invading pathogen, well fundamental fitness, even at trace amounts increasingly natural waterways.

Language: Английский

Citations

1