International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(16), P. 12826 - 12826
Published: Aug. 15, 2023
The
use
of
nanoparticles
like
graphene
oxide
(GO)
in
nanocomposite
industries
is
growing
very
fast.
There
a
strong
concern
that
GO
can
enter
the
environment
and
become
nanopollutatnt.
Environmental
pollutants'
exposure
usually
relates
to
low
concentrations
but
may
last
for
long
time
impact
following
generations.
Attention
should
be
paid
effects
nanoparticles,
especially
on
DNA
stability
passed
offspring.
We
investigated
multigenerational
two
strains
(wild
long-lived)
house
cricket
intoxicated
with
over
five
generations,
followed
by
one
recovery
generation.
Our
investigation
focused
oxidative
stress
parameters,
specifically
AP
sites
(apurinic/apyrimidinic
sites)
8-OHdG
(8-hydroxy-2'-deoxyguanosine),
examined
global
methylation
pattern.
Five
generations
were
able
overcome
stress,
showing
relatively
doses
have
moderate
effect
(8-OHdG
sites).
generation
experienced
transition
from
contaminated
uncontaminated
food
presented
greater
damage.
pattern
was
comparable
every
generation,
suggesting
other
epigenetic
mechanisms
might
involved.
Environment International,
Journal Year:
2023,
Volume and Issue:
177, P. 108002 - 108002
Published: June 1, 2023
Large-scale
plastic
pollution
occurs
in
terrestrial
and
marine
environments
degrades
into
microparticles
(MP)
nanoparticles
(NP)
of
plastic.
Micro/nanoplastics
(MP/NPs)
are
found
throughout
the
environment
different
kinds
organisms
can
enter
human
body
through
inhalation
or
ingestion,
particularly
food
chain.
MPs/NPs
organisms,
affect
systems,
including
reproductive,
digestive,
nervous
systems
via
induction
stresses
such
as
oxidative
stress
endoplasmic
reticulum
stress.
This
paper
summarizes
effects
sizes
on
reproduction
invertebrates
vertebrates,
amplification
toxic
between
them
chain,
serious
threat
to
biodiversity,
and,
more
importantly,
imminent
challenge
reproductive
health.
There
is
a
need
strengthen
international
communication
cooperation
remediation
protection
biodiversity
build
sustainable
association
humans
other
organisms.
The Science of The Total Environment,
Journal Year:
2023,
Volume and Issue:
903, P. 166258 - 166258
Published: Aug. 12, 2023
In
recent
years,
microplastics
(MPs)
and
nanoplastics
(NPs)
have
caused
ubiquitous
environmental
pollution
raised
widespread
concern
about
their
potential
toxicity
to
human
health,
especially
in
the
reproductive
system.
Moreover,
infertility
affects
>15
%
of
couples
worldwide,
birth
rate
is
decreasing.
Environmental
factors
are
some
most
important
causes
infertility.
However,
little
known
effects
MPs
NPs
on
testes
ovaries.
These
particles
can
enter
body
primarily
via
ingestion,
inhalation,
skin
contact,
target
system
a
size-dependent
manner
disturb
germ
cell
other
somatic
development.
Our
study
systematically
reviewed
adverse
plastic
function
offers
valuable
insights
into
different
stages
cells
mechanisms.
synergistic
these
carried
contaminants
was
summarized.
Given
limited
research
scale,
shift
toward
innovative
technologies
adoption
multiple
omics
recommended
for
advancing
related
studies.
Further
needed
explore
based
size,
polymer
type,
shape,
toxins,
establish
effective
protective
measures,
develop
precision
medicine
targeted
damage.
Journal of Toxicology and Environmental Health Part B,
Journal Year:
2024,
Volume and Issue:
27(4), P. 153 - 187
Published: March 22, 2024
The
widespread
production
and
use
of
plastics
have
resulted
in
accumulation
plastic
debris
the
environment,
gradually
breaking
down
into
smaller
particles
over
time.
Nano-plastics
(NPs)
microplastics
(MPs),
defined
as
than
100
nanometers
5
millimeters,
respectively,
raise
concerns
due
to
their
ability
enter
human
body
through
various
pathways
including
ingestion,
inhalation,
skin
contact.
Various
investigators
demonstrated
that
these
may
produce
physical
chemical
damage
cells,
tissues,
organs,
disrupting
cellular
processes,
triggering
inflammation
oxidative
stress,
impacting
hormone
neurotransmitter
balance.
In
addition,
micro-
nano-plastics
(MNPLs)
carry
toxic
chemicals
pathogens,
exacerbating
adverse
effects
on
health.
magnitude
nature
are
not
yet
fully
understood,
requiring
further
research
for
a
comprehensive
risk
assessment.
Nevertheless,
evidence
available
suggests
environment
potential
uptake
causes
concern.
Urgent
measures
reduce
pollution
limit
exposure
MNPLs
necessary
safeguard
health
environment.
this
review,
current
knowledge
regarding
influence
is
summarized,
toxicity
mechanisms,
pathways,
outcomes
across
multiple
organs.
critical
need
additional
also
emphasized
comprehensively
assess
risks
posed
by
degradation
inform
strategies
addressing
emerging
environmental
challenge.
Finally,
new
directions
proposed
evaluation
gene
regulation
associated
with
exposure.
Journal of Hazardous Materials,
Journal Year:
2024,
Volume and Issue:
477, P. 135299 - 135299
Published: July 22, 2024
The
increasing
accumulation
of
small
plastic
particles,
in
particular
microplastics
(>1
µm
to
5
mm)
and
nanoplastics
(<
1
µm),
the
environment
is
a
hot
topic
our
rapidly
changing
world.
Recently,
studies
were
initiated
better
understand
behavior
micro-
(MNP)
within
complex
matrices
like
soil,
as
well
their
characterization,
incorporation
potential
toxicity
terrestrial
biota.
However,
there
remains
significant
knowledge
gaps
understanding
wide-extent
impacts
MNP
on
invertebrates.
We
first
summarized
facts
global
pollution
generation
MNP.
Then,
we
focused
compiling
existing
literature
examining
consequences
exposure
diversity
investigated
biological
endpoints
(from
molecular
individual
levels)
compiled
get
comprehension
effects
according
different
factors
such
shape,
polymer
type,
organism,
concentration
duration.
sublethal
are
acknowledged
literature,
yet
no
general
conclusion
was
drawn
highly
dependent
characteristic
experimental
design.
Finally,
synthesis
highlighted
some
research
remediation
strategies,
protocol
standardize
ecotoxicological
studies.
The Science of The Total Environment,
Journal Year:
2024,
Volume and Issue:
927, P. 172252 - 172252
Published: April 9, 2024
Plastics
are
ubiquitous
in
our
daily
life.
Large
quantities
of
plastics
leak
the
environment
where
they
weather
and
fragment
into
micro-
nanoparticles.
This
potentially
releases
additives,
but
rarely
leads
to
a
complete
mineralization,
thus
constitutes
an
environmental
hazard.
Plastic
pollution
agricultural
soils
currently
represents
major
challenge:
quantitative
data
nanoplastics
as
well
their
effects
on
biodiversity
ecosystem
functions
need
more
attention.
accumulation
interferes
with
soil
functions,
including
water
dynamics,
aeration,
microbial
activities,
nutrient
cycling
processes,
impairing
crop
yield.
debris
directly
affects
living
organisms
also
acts
contaminant
vectors
soils,
increasing
threats
biodiversity.
Finally,
terrestrial
invertebrates,
representing
taxa
abundance
diversity
compartment,
urgently
investigation
from
infra-individual
scales.
Toxicology Reports,
Journal Year:
2025,
Volume and Issue:
14, P. 102013 - 102013
Published: April 1, 2025
The
harmful
environmental
impact
of
plastic
waste
has
justifiably
received
substantial
attention
from
the
scientific
community.
In
contrast,
toxicological
effects
nanoplastics
(NP)
on
aquatic
organisms,
as
well
potential
implications
for
human
health,
remain
largely
unexplored
and
poorly
understood.
Despite
growing
awareness
pollution,
risks
associated
with
ubiquitous
presence
in
our
food
beverages
are
not
yet
fully
recognized.
NPs,
which
smaller
than
1
µm,
along
a
mixture
MPs
fragments,
can
find
their
way
into
water
bodies
through
various
sources
may
easily
be
taken
up
by
organisms.
This
paper
summarizes
existing
literature
NPs
bioavailability,
accumulation
patterns
within
tissues
fish,
shellfish,
zooplankton,
influence
biological
factors
absorption
diet.
Study
indicated
that
pose
significant
to
both
ecosystems
health
due
ability
bioaccumulate
marine
organisms
biomagnify
web.
It
highlighted
species
ingest
leading
distribution
across
different
tissues,
result
toxic
such
oxidative
stress,
DNA
damage,
inflammation,
impacts
growth
reproduction.
identified
critical
gaps
current
research,
particularly
regarding
long-term
low-dose
NP
exposure
need
standardized
testing
methodologies
ensure
comparability
studies.
Furthermore,
necessity
further
research
understand
pathways
humans
exposed
toxicokinetics,
chronic
issues.
Therefore,
more
studies
required
employ
rigorous
uniform
address
an
emerging
threat
chains;
accurately
assess
related
together
cumulative
toxicity
perhaps
when
combined
other
pollutants.
