Illuminating anions in biology with genetically encoded fluorescent biosensors DOI

Mariah Cook,

Shelby M. Phelps, Jasmine N. Tutol

et al.

Current Opinion in Chemical Biology, Journal Year: 2024, Volume and Issue: 84, P. 102548 - 102548

Published: Dec. 9, 2024

Language: Английский

Overcoming key challenges: Next-generation synthetic anion transporters DOI
Jennifer R. Hiscock

Chem, Journal Year: 2025, Volume and Issue: 11(1), P. 102394 - 102394

Published: Jan. 1, 2025

Language: Английский

Citations

0
Uncovering the potent antimicrobial activity of squaramide based anionophores – chloride transport and membrane disruption DOI Creative Commons
Luke E. Brennan, Xuanyang Luo, Farhad Ali Mohammed

et al.

Chemical Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Squaramide derivatives that can efficiently bind to Cl − and exhibit potent transport in model liposomes demonstrate antimicrobial activity through a combination of disrupted chloride homeostasis membrane disruption.

Language: Английский

Citations

0
Anion transport in biologically relevant lipid mixtures DOI
Krystyna Maslowska-Jarzyna,

Sarah Rooijmans,

Daniel A. McNaughton

et al.

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

A potent squaramide-based anion transporter was used to evaluate how vesicles prepared with tailored lipid compositions, which mimic organelle membranes, can impact transmembrane transport.

Language: Английский

Citations

0
Design, synthesis and biological evaluation of Golgi-targeting anion transporters as inducers of Golgiphagy and apoptosis in cancer cells DOI
Haodong Yang, Li Chen,

Zixing Jiang

et al.

European Journal of Medicinal Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 117519 - 117519

Published: March 1, 2025

Language: Английский

Citations

0
Therapeutic synthetic anion transporters DOI Creative Commons
Elba Feo, Philip A. Gale

Current Opinion in Chemical Biology, Journal Year: 2024, Volume and Issue: 83, P. 102535 - 102535

Published: Sept. 27, 2024

This short review highlights recent examples of small-molecule anion transporters reported in the literature that have potentially useful biological activity. includes anionophores with antibiotic or antifungal activity, anticancer potential to treat channelopathies such as cystic fibrosis. Additionally selective and targeted are also discussed.

Language: Английский

Citations

2
Illuminating anions in biology with genetically encoded fluorescent biosensors DOI

Mariah Cook,

Shelby M. Phelps, Jasmine N. Tutol

et al.

Current Opinion in Chemical Biology, Journal Year: 2024, Volume and Issue: 84, P. 102548 - 102548

Published: Dec. 9, 2024

Language: Английский

Citations

0