Natural polysaccharides: The potential biomacromolecules for treating diabetes and its complications via AGEs-RAGE-oxidative stress axis DOI
Jie Sun, Na Wei, Chenxi Yu

et al.

International Immunopharmacology, Journal Year: 2024, Volume and Issue: 143, P. 113426 - 113426

Published: Oct. 30, 2024

Language: Английский

Phytochemical-based therapeutics from traditional eastern medicine: analgesic effects and ion channel modulation DOI Creative Commons
Sung Eun Kim, Geehoon Chung, Sun Kwang Kim

et al.

Frontiers in Pain Research, Journal Year: 2025, Volume and Issue: 6

Published: Jan. 31, 2025

Pain management remains a major challenge in the healthcare system. While synthetic analgesics are widely used for pain management, their effectiveness managing chronic is often limited due to low efficacy or side effects. Thus, there growing interest exploring alternative relief methods, particularly using medicinal plants from traditional Eastern medicine and phytochemicals. Previous studies have demonstrated modulatory effects of various phytochemicals derived herbal on pain-related ion channels, such as voltage-gated sodium channels (Nav), calcium (Ca2+), transient receptor potential (TRP) channels. Since these integral transmission modulation signals, ability specific activate inhibit presents promising avenue development novel analgesics. The goal this review merge insights with channel research highlight natural compounds safe effective management. In regard, we summarize discovery characterization pain-relieving medicine, discuss mechanisms action mimic enhance conventional through modulation.

Language: Английский

Citations

1
Stir-frying duration modulates structural characterization and functional properties of Atractylodes macrocephala polysaccharides DOI
Wei Li, Xiaoxiao Wang, Xiuyan Sun

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 306, P. 141489 - 141489

Published: Feb. 27, 2025

Language: Английский

Citations

1
Ultrasound-assisted extraction and antioxidant activity of triterpenoid saponins from Platycodon grandiflorum roots: Optimization, purification, and molecular insights DOI Creative Commons
Wei Li,

Yanqing Zhang,

Yinghao Wei

et al.

Industrial Crops and Products, Journal Year: 2024, Volume and Issue: 223, P. 119877 - 119877

Published: Oct. 23, 2024

Language: Английский

Citations

6
Exploring the Protective Effects of Spinosin Against Advanced Glycation End Product-Induced Cellular Damage Through Modulation RAGE/MAPK/ NF-κB pathway DOI
Wei Li, Yanqing Zhang, Na Tian

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 105951 - 105951

Published: Jan. 1, 2025

Language: Английский

Citations

0
Melanoidins from stir-frying Atractylodes Macrocephala: Structural characterization, molecular weight distribution, and polyphenol delivery mechanism DOI
Wei Li, Yajie Zhang, Xiaoxiao Wang

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 144238 - 144238

Published: April 1, 2025

Language: Английский

Citations

0
Natural polysaccharides: The potential biomacromolecules for treating diabetes and its complications via AGEs-RAGE-oxidative stress axis DOI
Jie Sun, Na Wei, Chenxi Yu

et al.

International Immunopharmacology, Journal Year: 2024, Volume and Issue: 143, P. 113426 - 113426

Published: Oct. 30, 2024

Language: Английский

Citations

3