Herbal medicine derived carbon dots: synthesis and applications in therapeutics, bioimaging and sensing

Journal of Nanobiotechnology, Journal Year: 2021, Volume and Issue: 19(1)

Published: Oct. 13, 2021

Abstract Since the number of raw material selections for synthesis carbon dots (CDs) has grown extensively, herbal medicine as a precursor receives an increasing amount attention. Compared with other biomass precursors, CDs derived from (HM-CDs) have become most recent incomer in family CDs. In ten years, great many studies revealed that HM-CDs tend to be good at theranostics without drug loading. However, relevant development and research results are not systematically reviewed. Herein, origin history outlined, especially their functional performances medical diagnosis treatment. Besides, we sort out analyze primary synthetic methods key characteristics. terms applications HM-CDs, therapeutics, ion molecular detection, bioimaging, well pH sensing summarized. Finally, discuss crucial challenges future prospects.

Language: Английский

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Perspectives of magnetic nature carbon dots in analytical chemistry: From separation to detection and bioimaging

Trends in Environmental Analytical Chemistry, Journal Year: 2021, Volume and Issue: 33, P. e00153 - e00153

Published: Nov. 30, 2021

Language: Английский

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<p>Selenium-Doped Carbon Quantum Dots Efficiently Ameliorate Secondary Spinal Cord Injury via Scavenging Reactive Oxygen Species</p>

International Journal of Nanomedicine, Journal Year: 2020, Volume and Issue: Volume 15, P. 10113 - 10125

Published: Dec. 1, 2020

The excess production of reactive oxygen species (ROS) after traumatic spinal cord injury (TSCI) has been identified as a leading cause secondary injury, which can significantly exacerbate acute damage in the injured cord. Thus, scavenging ROS emerged an effective route to ameliorate injury.Selenium-doped carbon quantum dots (Se-CQDs) with ability scavenge were prepared and used for efficiently ameliorating TSCI.Water-soluble Se-CQDs easily synthesized via hydrothermal treatment l-selenocystine. chemical structure, size, morphology characterized detail. biocompatibility protective effects against H2O2-induced oxidative investigated vitro. Moreover, behavioral test, bladder function, histological observation, Western blot investigate neuroprotective effect rat model contusion TSCI.The obtained exhibited good remarkable astrocytes PC12 cells. displayed marked anti-inflammatory anti-apoptotic activities, thereby reduced formation glial scars increased survival neurons unscathed myelin sheaths vivo. As result, capable largely improving locomotor function rats TSCI.This study suggests that be promising therapeutic platform TSCI.

Language: Английский

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Big family of nano- and microscale drug delivery systems ranging from inorganic materials to polymeric and stimuli-responsive carriers as well as drug-conjugates

Journal of Drug Delivery Science and Technology, Journal Year: 2021, Volume and Issue: 66, P. 102790 - 102790

Published: Aug. 16, 2021

Language: Английский

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Recent developments in carbon dot-based green analytical methods: new opportunities in fluorescence assays of pesticides, drugs and biomolecules

New Journal of Chemistry, Journal Year: 2022, Volume and Issue: 46(30), P. 14287 - 14308

Published: Jan. 1, 2022

Fluorescent carbon dots (CDs) attract huge attention in analytical and bioanalytical applications due to their high selectivity towards target analytes, specificity, photostability, quantum yield.

Language: Английский

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