Role of 3D printing in healthcare: A comprehensive review on treatment and training DOI
Maruf Nizam, Rajesh Purohit, Mohammad Taufik

et al.

Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: March 22, 2025

Additive manufacturing (AM) is revolutionizing healthcare by enabling the creation of customized 3D printed (3DP) medical equipment, implants, orthoses, prosthetics, drugs, and organs. With availability different types materials suitable for 3DP applications, this technology allows precise fabrication patient-oriented dental orthopedic devices, significantly improving fit functionality. Additionally, such as Oral Dispersible Formulations (ODFs) polypills, are surpassing traditional “one pill fits all” concept, offering more tailored medication solutions. This innovation also supports development personalized medications bioprinted tissues, opening way advancements in regenerative therapies. 3D-bioprinted organs addressing growing demand organ transplants. In surgical planning, 3D-printed anatomical models provide students professionals with hands-on practice, which crucial skill understanding complex anatomies. Surgeons can practice refine techniques before actual procedures, enhancing precision outcomes during real operations. paper focus on highlighting progression motivations behind cross-disciplinary applications AM within sector providing drug delivery systems diagnostic tools treatment refinement. designed a broad audience, including researchers, who interested exploring implications transformative technology.

Language: Английский

Progress in hydrogel toughening: addressing structural and crosslinking challenges for biomedical applications DOI Creative Commons
Md. Mahamudul Hasan Rumon, Md. Sohanur Rahman, Anwarul Azim Akib

et al.

Discover Materials, Journal Year: 2025, Volume and Issue: 5(1)

Published: Jan. 9, 2025

Achieving the ideal replacement for robust biological tissues requires biocompatible materials with a nuanced blend of characteristics, including organ specific toughness, durability, self-repairing capability, and well-defined structure. Hydrogels, structured high water containing 3D-crosslinked polymeric networks, present promising avenue in biomedical applications due to their close resemblance natural tissues. However, mechanical performance often falls short, limiting clinical applications. Recent research has been focused on developing hydrogel therapeutic advancements have spurred researchers develop hydrogels having acceptable toughness. While it is now possible tailor properties synthetic gels mimic those tissues, critical aspects such as biocompatibility crosslinking strategies are frequently neglected. This review scrutinizes structural techniques designed improve toughness hydrogels, focusing especially innovative efforts integrate these enhancements into natural-based hydrogels. By thoroughly examining methodologies, sheds light complexities strengthening will propose valuable insights development next-generation tissue substitutes.

Language: Английский

Citations

8
Localized assembly in biological activity: Origin of life and future of nanoarchitectonics DOI
Jingwen Song, Kohsaku Kawakami, Katsuhiko Ariga

et al.

Advances in Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 339, P. 103420 - 103420

Published: Feb. 3, 2025

Language: Английский

Citations

3
3D-printed cellulose nanocrystals and gelatin scaffolds with bioactive cues for regenerative medicine: Advancing biomedical applications DOI
Prerna Singh, Hossein Baniasadi, Sneha Gupta

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 278, P. 134402 - 134402

Published: July 31, 2024

Language: Английский

Citations

13
Ink formulation in direct ink writing of ceramics: A meta-analysis DOI
Z. Li, Shitong Zhou, Eduardo Saiz

et al.

Journal of the European Ceramic Society, Journal Year: 2024, Volume and Issue: 44(12), P. 6777 - 6796

Published: May 10, 2024

Language: Английский

Citations

9
Applications of Artificial Intelligence and Machine Learning on Critical Materials Used in Cosmetics and Personal Care Formulation Design DOI
Hai Xin, Akashdeep Singh Virk,

Sabitoj Singh Virk

et al.

Current Opinion in Colloid & Interface Science, Journal Year: 2024, Volume and Issue: 73, P. 101847 - 101847

Published: Aug. 3, 2024

Language: Английский

Citations

8
Direct Ink Writing of Conductive Hydrogels DOI Creative Commons
Monica Ho, Aline Braz Ramirez,

Negar Akbarnia

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

Abstract Direct ink writing (DIW) is an additive manufacturing technique that has garnered notable interest due to its precise and consistent printing of a wide range materials, such as viscoelastic hydrogels, pastes, complex composites, by adjusting the ink's rheology. This material flexibility combined with ability print at room temperature makes DIW ideal for diverse applications scalable from small industrial levels. In recent years, conductive hydrogels gained significant attention across various fields, ranging biomedical scaffolds flexible electronics. Conductive are category which exhibit conductivity in their wet and/or dry state. Precursors like polymers, metallic nanoparticles, carbon‐based materials can be used induce electronic ionic hydrogels. review presents comprehensive overview demonstrating printability using technique. The fundamentals precursors presented. Following, different pathways reaching optimal hydrogel properties, including mechanical, conductive, rheological, focus on synthesis introduced. Finally, emerging electronics medicine highlighted, anticipated challenges advancement printable discussed.

Language: Английский

Citations

1
3D printing driving innovations in extreme low-temperature energy storage DOI Creative Commons

Shutong Qin,

Jiao Dai, Haoran Tian

et al.

Virtual and Physical Prototyping, Journal Year: 2025, Volume and Issue: 20(1)

Published: Feb. 6, 2025

Extreme low-temperature environments, such as those in aerospace, polar expeditions, and deep-sea exploration, demand efficient energy storage systems. Conventional technologies face major limitations under these conditions, including electrolyte freezing, restricted interfacial reaction kinetics, microstructural instability. In contrast, 3D printing offers transformative solutions with precise control, multifunctional material integration, optimisation, effectively addressing challenges related to compatibility structural complexity. However, the mechanisms for optimising performance remain poorly understood, of processes materials needs further exploration. Moreover, comprehensive integration materials, processes, device designs remains an ongoing challenge. This review systematically summarises key their characteristics storage, exploring potential pathways through which enhances performance. Particular emphasis is placed on its unique applications design, engineering, multi-material coupling. Unlike studies focused single or technologies, this adopts interdisciplinary systematic framework, linking properties optimisation. It provides critical theoretical guidance practical insights advancing scientific understanding engineering extreme technologies.

Language: Английский

Citations

1
Hybrid 3D Bioprinting of Sustainable Biomaterials for Advanced Multiscale Tissue Engineering DOI Open Access
Xuejiao Ma,

Mingqi Xu,

Xiaolin Cui

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Abstract 3D printing has greatly improved the precision of cell and biomaterial placement, enabling accurate reproduction tissue models with sustainable potential. Various techniques, including inkjet printing, extrusion‐based vat photopolymerization, offer unique advantages but often fail to replicate full complexity native tissues because material scalability limitations. Hybrid bioprinting, combining multiple techniques in a single process, shown great potential creating complex multifunctional capabilities, ranging from patient‐specific implant fabrication full‐scale organ development. It capitalizes on strengths integration sustainable, renewable biomaterials at varying resolutions, nano microscale. This approach addresses both biological environmental responsibility by minimizing waste enhancing sustainability engineering processes. Despite progress, substantial gap remains between current technologies bioengineering requirements. A deep understanding hybrid its underlying mechanisms is crucial. Herein, this review summarizes discusses recent advancements systems for fabricating multiscale hierarchical models, focusing challenges field. aims insights identify key requirements advancing technology toward developing functional, biomimetic constructs.

Language: Английский

Citations

1
Robust, stretchable bioelectronic interfaces for cardiac pacing enabled by interfacial transfer of laser-induced graphene via water-response, nonswellable PVA gels DOI
Lei Zhao, Zhiqiang Chang,

Bihan Guo

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 261, P. 116453 - 116453

Published: May 28, 2024

Language: Английский

Citations

7
Soft Actuators and Actuation: Design, Synthesis and Applications DOI
Mulenga Kalulu,

Bright Chilikwazi,

Jun Hu

et al.

Macromolecular Rapid Communications, Journal Year: 2024, Volume and Issue: unknown

Published: June 8, 2024

Abstract Soft actuators are one of the most promising technological advancements with potential solutions to diverse fields’ day‐to‐day challenges. derived from hydrogel materials possess unique features such as flexibility, responsiveness stimuli, and intricate deformations, making them ideal for soft robotics, artificial muscles, biomedical applications. This review provides an overview material composition design techniques actuators, exploring 3D printing, photopolymerization, cross‐linking, microfabrication methods improved actuation. It examines applications in biomedical, bioinspired systems, microfluidics, lab‐on‐a‐chip devices, environmental, energy systems. Finally, it discusses challenges, opportunities, advancements, regulatory aspects related actuators.

Language: Английский

Citations

7