International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(8), P. 7579 - 7579
Published: April 20, 2023
Mental
illness
is
alarmingly
on
the
rise,
and
circadian
disruptions
linked
to
a
modern
lifestyle
may
largely
explain
this
trend.
Impaired
rhythms
are
associated
with
mental
disorders.
The
evening
chronotype,
which
misalignment,
risk
factor
for
severe
psychiatric
symptoms
metabolic
comorbidities.
Resynchronization
of
commonly
improves
symptoms.
Furthermore,
evidence
indicates
that
preventing
misalignment
help
reduce
disorders
impact
neuro–immuno–metabolic
disturbances
in
psychiatry.
gut
microbiota
exhibits
diurnal
rhythmicity,
as
governed
by
meal
timing,
regulates
host’s
rhythms.
Temporal
regulation
feeding
has
emerged
promising
chronotherapeutic
strategy
prevent
and/or
treatment
illnesses,
through
modulation
microbiota.
Here,
we
provide
an
overview
link
between
disruption
illness.
We
summarize
connection
rhythms,
supporting
idea
aid
resynchronization
disrupted
describe
microbiome
rhythmicity
its
related
factors,
highlighting
role
timing.
Lastly,
emphasize
necessity
rationale
further
research
develop
effective
safe
dietary
strategies
based
chrononutrition
combat
The ISME Journal,
Journal Year:
2021,
Volume and Issue:
15(9), P. 2655 - 2664
Published: March 21, 2021
Abstract
Microbial
community
circadian
rhythms
have
a
broad
influence
on
host
health
and
even
though
light-induced
environmental
fluctuations
could
regulate
microbial
communities,
the
contribution
of
light
to
rhizosphere
communities
has
received
little
attention.
To
address
this
gap,
we
monitored
diel
changes
in
rice
(Oryza
sativa
L.)
soil
under
light–dark
constant
dark
regimes,
identifying
microbes
with
caused
by
exposure
clocks,
respectively.
While
displayed
taxa
possessing
two
conditions
were
dissimilar.
Light
concealed
clocks
as
regulatory
driver,
leading
fewer
ecological
niches
versus
communities.
These
findings
disentangle
regulation
mechanisms
for
highlight
role
Molecular Brain,
Journal Year:
2023,
Volume and Issue:
16(1)
Published: Jan. 12, 2023
Circadian
disruption
has
become
more
prevalent
in
society
due
to
the
increase
shift
work,
sleep
disruption,
blue
light
exposure,
and
travel
via
different
time
zones.
The
circadian
rhythm
is
a
timed
transcription-translation
feedback
loop
with
positive
regulators,
BMAL1
CLOCK,
that
interact
negative
CRY
PER,
regulate
both
central
peripheral
clocks.
This
review
highlights
functions
of
rhythm,
specifically
blood-brain
barrier
(BBB),
during
healthy
pathological
states.
BBB
highly
selective
dynamic
interface
composed
CNS
endothelial
cells,
astrocytes,
pericytes,
neurons,
microglia
form
neurovascular
unit
(NVU).
rhythms
modulate
integrity
through
regulating
oscillations
tight
junction
proteins,
assisting
NVU,
modulating
transporter
functions.
disruptions
within
have
been
observed
stress
responses
several
neurological
disorders,
including
brain
metastasis,
epilepsy,
Alzheimer's
disease,
Parkinson's
disease.
Further
understanding
these
interactions
may
facilitate
development
improved
treatment
options
preventative
measures.
International Journal of Molecular Sciences,
Journal Year:
2023,
Volume and Issue:
24(8), P. 7579 - 7579
Published: April 20, 2023
Mental
illness
is
alarmingly
on
the
rise,
and
circadian
disruptions
linked
to
a
modern
lifestyle
may
largely
explain
this
trend.
Impaired
rhythms
are
associated
with
mental
disorders.
The
evening
chronotype,
which
misalignment,
risk
factor
for
severe
psychiatric
symptoms
metabolic
comorbidities.
Resynchronization
of
commonly
improves
symptoms.
Furthermore,
evidence
indicates
that
preventing
misalignment
help
reduce
disorders
impact
neuro–immuno–metabolic
disturbances
in
psychiatry.
gut
microbiota
exhibits
diurnal
rhythmicity,
as
governed
by
meal
timing,
regulates
host’s
rhythms.
Temporal
regulation
feeding
has
emerged
promising
chronotherapeutic
strategy
prevent
and/or
treatment
illnesses,
through
modulation
microbiota.
Here,
we
provide
an
overview
link
between
disruption
illness.
We
summarize
connection
rhythms,
supporting
idea
aid
resynchronization
disrupted
describe
microbiome
rhythmicity
its
related
factors,
highlighting
role
timing.
Lastly,
emphasize
necessity
rationale
further
research
develop
effective
safe
dietary
strategies
based
chrononutrition
combat
