Journal of the International Society of Sports Nutrition,
Journal Year:
2025,
Volume and Issue:
22(1)
Published: March 19, 2025
Background/Objective
Dietary
restriction
or
exercise
regimens
can
promote
weight
loss
physical
fitness
among
patients
with
obesity.
However,
intervention-associated
adverse
effects
may
impede
patients'
motivation
to
participate
in
dietary/exercise
interventions.
We
examined
the
of
time
restricted
eating
(TRE)
without
resistance
training
(RT)
on
body
composition,
mood
profile,
and
sleep
quality
young
college
adults
overweight
JAMA Network Open,
Journal Year:
2023,
Volume and Issue:
6(3), P. e233513 - e233513
Published: March 17, 2023
Importance
The
efficacy
and
safety
of
time-restricted
eating
(TRE)
on
nonalcoholic
fatty
liver
disease
(NAFLD)
remain
uncertain.
Objective
To
compare
the
effects
TRE
vs
daily
calorie
restriction
(DCR)
intrahepatic
triglyceride
(IHTG)
content
metabolic
risk
factors
among
patients
with
obesity
NAFLD.
Design,
Setting,
Participants
This
12-month
randomized
clinical
trial
including
participants
NAFLD
was
conducted
at
Nanfang
Hospital
in
Guangzhou,
China,
between
April
9,
2019,
August
28,
2021.
Interventions
were
randomly
assigned
to
(eating
only
8:00
am
4:00
pm
)
or
DCR
(habitual
meal
timing).
All
instructed
maintain
a
diet
1500
1800
kcal/d
for
men
1200
women
12
months.
Main
Outcomes
Measures
primary
outcome
change
IHTG
measured
by
magnetic
resonance
imaging;
secondary
outcomes
changes
body
weight,
waist
circumference,
fat,
factors.
Intention-to-treat
analysis
used.
Results
A
total
88
eligible
(mean
[SD]
age,
32.0
[9.5]
years;
49
[56%];
mean
mass
index,
32.2
[3.3])
(n
=
45)
43)
group.
reduced
8.3%
(95%
CI,
−10.0%
−6.6%)
group
8.1%
−9.8%
−6.4%)
6-month
assessment.
6.9%
−8.8%
−5.1%)
7.9%
−9.7%
−6.2%)
Changes
comparable
2
groups
6
months
(percentage
point
difference:
−0.2;
95%
−2.7
2.2;
P
.86)
1.0;
−1.6
3.5;
.45).
In
addition,
stiffness,
significantly
comparably
both
groups.
Conclusions
Relevance
Among
adults
NAFLD,
did
not
produce
additional
benefits
reducing
content,
compared
DCR.
These
findings
support
importance
caloric
intake
when
adhering
regimen
management
Trial
Registration
ClinicalTrials.gov
Identifiers:
NCT03786523
NCT04988230
Frontiers in Public Health,
Journal Year:
2023,
Volume and Issue:
11
Published: Oct. 13, 2023
Aging
is
a
progressive
and
irreversible
pathophysiological
process
that
manifests
as
the
decline
in
tissue
cellular
functions,
along
with
significant
increase
risk
of
various
aging-related
diseases,
including
metabolic
diseases.
While
advances
modern
medicine
have
significantly
promoted
human
health
extended
lifespan,
diseases
such
obesity
type
2
diabetes
among
older
adults
pose
major
challenge
to
global
public
societies
age.
Therefore,
understanding
complex
interaction
between
factors
crucial
for
promoting
well-being
healthy
aging.
This
review
article
explores
environmental
behavioral
associated
their
impact
on
The
environment,
an
obesogenic
environment
exposure
toxins,
strongly
correlated
rising
prevalence
its
comorbidities.
Behavioral
factors,
diet,
physical
activity,
smoking,
alcohol
consumption,
sleep
patterns,
influence
throughout
Public
interventions
targeting
modifiable
can
effectively
promote
healthier
lifestyles
prevent
Collaboration
government
agencies,
healthcare
providers
community
organizations
essential
implementing
these
creating
supportive
environments
foster
JAMA Network Open,
Journal Year:
2024,
Volume and Issue:
7(3), P. e241147 - e241147
Published: March 5, 2024
Importance
Understanding
the
interplay
between
sleep
duration,
dietary
habits,
and
risk
of
developing
type
2
diabetes
(T2D)
is
crucial
for
public
health
prevention
strategies.
Objective
To
investigate
associations
diet
duration
with
development
T2D.
Design,
Setting,
Participants
Data
derived
from
UK
Biobank
baseline
investigation
(2006-2010)
were
analyzed
this
cohort
study
May
1
September
30,
2023.
The
association
healthy
patterns
T2D
was
investigated
during
a
median
(IQR)
follow-up
12.5
(11.8-13.2)
years
(end
follow-up,
2021).
Exposure
For
analysis,
247
867
participants
categorized
into
4
groups:
normal
(7-8
hours
per
day),
mild
short
(6
moderate
(5
extreme
(3-4
day).
Their
habits
evaluated
based
on
population-specific
consumption
red
meat,
processed
fruits,
vegetables,
fish,
resulting
in
score
ranging
0
(unhealthiest)
to
5
(healthiest).
Main
Outcomes
Measures
Cox
proportional
hazards
regression
analysis
used
calculate
hazard
ratios
(HRs)
95%
CIs
across
various
groups
scores.
Results
comprised
mean
[SD]
age
55.9
[8.1]
years,
whom
52.3%
female.
During
3.2%
diagnosed
hospital
registry
data.
adjusted
confounding
variables,
indicated
significant
increase
among
or
less
daily
sleep.
Individuals
sleeping
day
exhibited
1.16
HR
(95%
CI,
1.05-1.28),
individuals
3
1.41
1.19-1.68)
compared
duration.
Furthermore,
healthiest
had
reduced
(HR,
0.75
[95%
0.63-0.88]).
increased
persisted
even
following
diet,
but
there
no
multiplicative
interaction
score.
Conclusions
Relevance
In
involving
residents,
habitual
associated
This
who
maintained
diet.
validate
these
findings,
further
longitudinal
studies
are
needed,
incorporating
repeated
measures
(including
objective
assessments)
habits.
Frontiers in Nutrition,
Journal Year:
2023,
Volume and Issue:
10
Published: March 2, 2023
Physiologically,
the
intestinal
barrier
plays
a
crucial
role
in
homeostasis
and
nutrient
absorption
prevents
pathogenic
entry,
harmful
metabolites,
endotoxin
absorption.
Recent
advances
have
highlighted
association
between
severely
damaged
barriers
diabetes,
obesity,
fatty
liver,
cardiovascular
diseases.
Evidence
indicates
that
an
abated
leads
to
endotoxemia
associated
with
systemic
inflammation,
insulin
resistance,
lipid
accumulation,
accelerating
obesity
liver
Nonetheless,
specific
mechanism
of
damage
effective
improvement
remain
be
explored.
Here,
we
discuss
crosstalk
changes
metabolic
disease.
This
paper
also
highlights
how
improve
gut
from
perspective
natural
medicine,
microbiota
remodeling,
lifestyle
interventions,
bariatric
surgery.
Finally,
potential
challenges
prospects
for
regulation
barrier-metabolic
disease
axis
are
discussed,
which
may
provide
theoretical
guidance
treatment
Nutrition Journal,
Journal Year:
2024,
Volume and Issue:
23(1)
Published: Jan. 6, 2024
Abstract
Introduction
and
aim
Exercise
training
(Ex)
intermittent
fasting
(IF)
are
effective
for
improving
body
composition
cardiometabolic
health
overweight
obese
adults,
but
whether
combining
Ex
IF
induces
additive
or
synergistic
effects
is
less
well
established.
We
therefore,
performed
a
systematic
review
meta-analysis
to
compare
the
combined
versus
independent
of
on
in
adults.
Method
An
electronic
search
was
conducted
three
main
online
databases
including
PubMed,
Web
Science,
Scopus,
from
inception
March
9,
2023
studies
involving
plus
trials
standalone
and/or
interventions
Interventions
had
duration
≥
2
weeks.
Standardized
(SMD)
weighted
mean
differences
(WMD)
95%
confidence
intervals
were
calculated
order
weight,
mass
index
(BMI),
fat
lean
(LBM),
visceral
fat,
waist
circumference.
For
health,
outcomes
included
glucose,
insulin,
total
cholesterol
(TC),
low-density
lipoprotein
(LDL),
triglycerides
(TG),
high-density
(HDL),
systolic
(SBP)
diastolic
(DBP)
blood
pressure,
VO
max/peak.
Results
decreased
weight
[WMD:
-3.03
kg
(95%
CI:
-3.44
-2.61),
p
=
0.001],
BMI
-1.12
kg.m
-1.28
-0.95),
[SMD:
-0.72
-1.23
-0.21),
0.005],
-0.34
-0.63
-0.05),
0.01],
circumference
-2.63
cm
-4.16
-1.11),
0.001]
more
than
alone.
However,
changes
markers
not
significantly
different
when
compared
with
alone,
exception
max/peak
0.55
0.14
0.97),
0.009].
Conclusion
demonstrate
that
combination
produces
superior
composition,
could
therefore
be
loss
has
no
other
markers.
Journal of Pineal Research,
Journal Year:
2024,
Volume and Issue:
76(4)
Published: May 1, 2024
Abstract
The
circadian
timing
system
controls
glucose
metabolism
in
a
time‐of‐day
dependent
manner.
In
mammals,
the
consists
of
main
central
clock
bilateral
suprachiasmatic
nucleus
(SCN)
anterior
hypothalamus
and
subordinate
clocks
peripheral
tissues.
oscillations
produced
by
these
different
with
period
approximately
24‐h
are
generated
transcriptional‐translational
feedback
loops
set
core
genes.
Glucose
homeostasis
is
one
daily
rhythms
controlled
this
system.
pacemaker
SCN
through
its
neural
projections
to
hypothalamic
hubs
that
control
feeding
behavior
energy
metabolism.
Using
hormones
such
as
adrenal
glucocorticoids
melatonin
autonomic
nervous
system,
modulates
critical
processes
production
insulin
sensitivity.
Peripheral
tissues,
liver,
muscle,
adipose
tissue
serve
enhance
sustain
signals.
optimal
situation
all
synchronized
aligned
environmental
light/dark
cycle.
A
negative
impact
on
becomes
apparent
when
internal
disturbed,
also
known
desynchrony
or
misalignment.
Circadian
may
occur
at
several
levels,
mistiming
light
exposure
sleep
will
especially
affect
clock,
whereas
food
intake
physical
activity
involve
clocks.
review,
we
summarize
literature
investigating
how
it
result
development
resistance.
addition,
discuss
potential
strategies
aimed
reinstating
synchrony
improve
sensitivity
contribute
prevention
type
2
diabetes.
iScience,
Journal Year:
2024,
Volume and Issue:
27(2), P. 109000 - 109000
Published: Jan. 26, 2024
Time-restricted
eating
(TRE)
is
an
effective
way
to
lose
weight
and
improve
metabolic
health
in
animals.
Yet
whether
how
these
benefits
apply
humans
unclear.
This
systematic
review
meta-analysis
examined
the
effect
of
TRE
people
with
overweight
obesity
statuses.
The
results
showed
that
led
modest
loss,
lower
waist
circumference
energy
deficits.
also
improved
body
mass
index,
fat
mass,
lean
systolic
blood
pressure,
fasting
glucose
levels,
insulin
HbA1c%.
Subgroup
analysis
demonstrated
more
improvements
group
than
control
under
Frontiers in Nutrition,
Journal Year:
2024,
Volume and Issue:
11
Published: Feb. 15, 2024
Obesity
is
prevalent
with
the
adult
population
in
United
States.
Energy-dense
diets
and
erratic
eating
behavior
contribute
to
obesity.
Time-restricted
a
dietary
strategy
humans
that
has
been
advanced
reduce
propensity
for
We
hypothesized
time-restricted
feeding
(TRF)
would
improve
metabolic
flexibility
normalize
function
mice
established
excess
adiposity.
