A
light-emitting
organosilane
molecule
based
on
a
Ru-complex
was
synthesized
from
1,10-phenanthroline,
(3-Aminopropyl)triethoxysilane
(APTES),
ruthenium
trichloride,
and
2,2′-Bipyridine.
The
resulting
complex
covalently
attached
to
transparent
conductive
substrate,
Indium-Tin
Oxide
(ITO),
using
straightforward
dipping
method.
Surface
characterization
of
the
modified
substrates
conducted
through
X-ray
photoelectron
spectroscopy
(XPS)
electrochemical
experiments,
confirming
presence
covalent
bonds.
immobilized
film
ITO
demonstrated
robust
stability
as
electrode
holds
significant
promise
novel
material.
ChemBioChem,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 2, 2024
Electrochemiluminescence
(ECL)
is
one
of
the
most
powerful
techniques
that
meet
needs
analysis
and
detection
in
a
variety
scenarios,
because
its
highly
analytical
sensitivity
excellent
spatiotemporal
controllability.
ECL
combined
with
microscopy
(ECLM)
offers
promising
approach
for
quantifying
mapping
wide
range
analytes.
To
date,
ECLM
has
been
widely
used
to
image
biological
entities
processes,
such
as
cells,
subcellular
structures,
proteins
membrane
transport
properties.
In
this
review,
we
first
introduced
mechanisms
several
classic
systems,
then
highlighted
progress
visual
biosensing
bioimaging
by
last
decade.
Finally,
characteristics
were
summarized,
well
some
current
challenges.
The
future
research
interests
potential
directions
application
also
outlooked.
ACS Sensors,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 9, 2025
Tuberculosis
(TB)
is
a
highly
contagious
bacterial
infection
that
remains
leading
cause
of
death
and
persistent
threat
to
global
health.
The
spread
TB
exacerbated
by
the
major
limitations
conventional
diagnostic
approaches,
such
as
complex
technicalities,
high
cost,
low
sensitivity.
To
address
these
challenges,
recent
research
has
focused
on
using
electrochemiluminescence
(ECL)
an
alternative
detection
strategy
coupled
biosensors.
ECL
biosensors
leverage
electrochemically
generated
chemiluminescence,
converting
electrical
energy
light,
novel
transduction
mechanism
for
This
unique
approach
offers
several
advantages,
namely,
wide
linear
dynamic
ranges,
improved
device
sensitivities,
prompt
response
times
sensitive
early
detection.
Review
comprehensive
overview
advancements
in
biosensor
configurations,
including
amplification
strategies,
substrates,
development
luminophores
coreactants
tailored
biomarker
focus
designs,
biorecognition
elements
like
immunosensors,
DNA
sensors,
aptasensors,
along
with
various
immobilization
strategies
target
specific
biomarkers.
A
discussion
spans
trends
over
past
decade,
clinical
relevance,
sensitivity
thresholds,
limits.
Furthermore,
widely
recognized
biomarkers
commonly
detected
commercial
tests
are
discussed
alongside
markers
that,
while
not
exclusive
TB,
have
demonstrated
importance.
aims
highlight
potential
ECL-based
effective
means
advance
early,
reliable,
accessible
approach.
Chemical Communications,
Journal Year:
2023,
Volume and Issue:
59(51), P. 7900 - 7910
Published: Jan. 1, 2023
Electrogenerated
chemiluminescence
(ECL)
refers
to
the
phenomenon
of
light
emission
from
molecular
species
which
is
triggered
by
an
electrochemical
reaction.
Therefore,
like
most
systems,
electrode
material
plays
a
pivotal
role
and
much
effort
has
been
made
in
order
find
best
for
ECL,
terms
signal
intensity
long-term
stability,
especially
after
development
ECL
analytical
applications.
In
this
article,
we
will
introduce
highlight
distinctive
features
boron-doped
diamond
(BDD)
as
complementary
properties
compared
common
metals
(e.g.,
Au
or
Pt)
carbon
materials
glassy
carbon,
nanotubes
graphene).
Boron-doped
electrodes
emerged
novel
electrodes,
gaining
more
interest
community
their
peculiar
characteristics
such
wide
solvent
window,
low
capacitance,
resistance
fouling
mechanical
robustness.
Furthermore,
metal
BDD
does
not
form
oxide
layer
aqueous
solutions,
sp3
hybridization
gives
ability
enable
reactions
that
are
possible
on
sp2
materials.
investigations
with
have
reported
systems
(luminophores
co-reactants),
special
only
includes
situ
generation
co-reactant.
Molecules,
Journal Year:
2023,
Volume and Issue:
29(1), P. 1 - 1
Published: Dec. 19, 2023
The
excessive
concentration
of
heavy-metal
mercury
ions
(Hg2+)
in
the
environment
seriously
affects
ecological
and
even
threatens
human
health.
Therefore,
it
is
necessary
to
develop
rapid
low-cost
determination
methods
achieve
trace
detection
Hg2+.
In
this
paper,
an
Electrochemiluminescence
(ECL)
sensing
platform
using
a
functionalized
rare-earth
material
(cerium
oxide,
CeO2)
as
luminescent
unit
aptamer
capture
was
designed
constructed.
Using
specific
asymmetric
matching
between
Hg2+
thymine
(T)
base
pairs
deoxyribonucleic
acid
(DNA)
single
strand,
“T−Hg−T”
structure
formed
change
ECL
signal,
leading
direct
sensitive
response
results
show
good
linear
relationship
signal
within
range
10
pM–100
µM
for
Hg2+,
with
limit
low
0.35
pM.
addition,
probe
exhibits
stable
performance
excellent
specificity
identifying
target
It
then
successfully
used
spiked
recovery
tests
actual
samples
environment.
analytical
method
solves
problem
poor
recognition
specificity,
provides
new
idea
efficient
pollutant
environment,
broadens
prospects
development
application
materials.
ACS Omega,
Journal Year:
2022,
Volume and Issue:
7(43), P. 38709 - 38716
Published: Oct. 20, 2022
A
molybdenum
sulfide/zirconium
oxide/Nafion
(MoS2/ZrO2/Naf)
based
electrochemiluminescence
(ECL)
aptasensor
for
the
selective
and
ultrasensitive
detection
of
ApoA1
is
proposed,
with
Ru(bpy)32+
as
luminophore.
The
chitosan
(CS)
modification
on
nanocomposite
layer
allowed
glutaraldehyde
(GLUT)
cross-linking,
resulting
in
immobilization
aptamers.
Scanning
electron
microscopy,
tunneling
energy
dispersive
X-ray
spectroscopy
were
used
to
characterize
nanocomposite,
while
(ECL),
cyclic
voltammetry,
electrochemical
impedance
analyze
assembly.
was
an
electrode
modifier,
which
increased
intensity
ECL
signal.
Due
anionic
environment
produced
sensor
surface
following
specific
interaction
biomarker
sensor,
more
able
be
electrostatically
attached
aptamer-ApoA1
complex,
enhanced
demonstrated
outstanding
sensitivity
under
optimal
experimental
conditions,
a
limit
53
fg/mL
wide
linear
dynamic
range
0.1-1000
pg/mL.
potential
practical
applicability
this
validated
by
analyzing
human
serum
samples,
recovery
rates
94-108%
(n
=
3).
proposed
assay
found
substantially
better
compared
commercially
available
enzyme-linked
immunosorbent
method,
reflected
from
over
1500
times
improvement
ApoA1.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 20, 2024
Photoredox
catalysis
is
a
powerful
tool
to
access
challenging
and
diverse
syntheses.
Absorption
of
visible
light
forms
the
excited
state
catalyst
(*PC)
but
photons
may
be
wasted
if
one
several
unproductive
pathways
occur.
Facile
dissociation
charge-separated
encounter
complex
[PC
