Journal of Experimental Biology,
Journal Year:
2020,
Volume and Issue:
unknown
Published: Jan. 1, 2020
The
fat
body,
a
major
metabolic
hub
in
insects,
is
involved
many
functions,
e.g.
energy
storage,
nutrient
sensing
and
immune
response.
In
social
appears
to
play
an
additional
role
division
of
labour
between
egg
layers
workers,
which
specialize
non-reproductive
tasks
inside
outside
their
nest.
For
instance,
reproductives
are
more
resistant
starvation,
changes
content
have
been
associated
with
the
transition
from
work
or
reproductive
activities.
However,
most
studies
correlative
we
still
need
unravel
causal
interrelationships
both
labour.
Clonal
ants,
Platythyrea
punctata,
ideal
models
for
studying
task
partitioning
without
confounding
variation
genotype
morphology.
this
study,
examined
range
flexibility
throughout
lifespan
threshold
corpulence
foraging
reproduction
whether
low
cause
rather
than
consequence
foraging.
We
found
that
lipid
stores
change
corpulent
lean
and,
reverted
nurses,
back
corpulent.
addition,
our
data
show
presence
thresholds
trigger
onset
egg-laying
behaviour.
Our
study
supports
view
mechanisms
regulate
solitary
particular
nutritional
status
individuals,
co-opted
colonies
insects.
Diet
plays
a
significant
role
in
maintaining
lifelong
health.
In
particular,
lowering
the
dietary
protein:
carbohydrate
ratio
can
improve
lifespan.
This
has
been
interpreted
as
direct
effect
of
these
macronutrients
on
physiology.
Using
Drosophila
melanogaster
,
we
show
that
protein
and
lifespan
is
indirect,
acting
by
altering
partitioning
limiting
amounts
sterols
between
reproduction
Shorter
lifespans
flies
fed
high
diets
be
rescued
supplementing
their
food
with
cholesterol.
Not
only
does
this
fundamentally
alter
way
interpret
mechanisms
extension
restriction,
data
highlight
important
principle
life
histories
affected
nutrient-dependent
trade-offs
are
indirect
independent
nutrients
(often
macronutrients)
focus
study.
brings
us
closer
to
understanding
mechanistic
basis
restriction.
PLoS Genetics,
Journal Year:
2020,
Volume and Issue:
16(11), P. e1009110 - e1009110
Published: Nov. 20, 2020
Organisms
living
in
seasonally
variable
environments
utilize
cues
such
as
light
and
temperature
to
induce
plastic
responses,
enabling
them
exploit
favorable
seasons
avoid
unfavorable
ones.
Local
adapation
can
result
variation
seasonal
but
the
genetic
basis
evolutionary
history
of
this
remains
elusive.
Many
insects,
including
Drosophila
melanogaster,
are
able
undergo
an
arrest
reproductive
development
(diapause)
response
conditions.
In
D.
ability
diapause
is
more
common
high
latitude
populations,
where
flies
endure
harsher
winters,
spring,
reflecting
differential
survivorship
overwintering
populations.
Using
a
novel
hybrid
swarm-based
genome
wide
association
study,
we
examined
ovarian
diapause.
We
exposed
outbred
females
different
temperatures
day
lengths,
characterized
for
over
2800
flies,
reconstructed
their
complete,
phased
genomes.
found
that
diapause,
scored
at
two
developmental
cutoffs,
has
modest
heritability,
identified
hundreds
SNPs
associated
with
each
phenotypes.
Alleles
one
phenotypes
tend
be
higher
latitudes,
these
alleles
do
not
show
predictable
variation.
The
collective
signal
many
small-effect,
clinally
varying
plausibly
explain
latitudinal
seen
North
America.
segregating
Zambia,
suggesting
relies
on
ancestral
polymorphisms,
both
pro-
anti-diapause
have
experienced
selection
Finally,
utilized
outdoor
mesocosms
track
under
natural
swarms
reared
outdoors
evolved
increased
propensity
late
fall,
whereas
indoor
control
populations
no
change.
Our
results
indicate
complex,
quantitative
trait
patterns
across
time
space.
International Journal of Molecular Sciences,
Journal Year:
2024,
Volume and Issue:
25(8), P. 4482 - 4482
Published: April 19, 2024
Lifespan
is
a
complex
quantitative
trait
involving
genetic
and
non-genetic
factors
as
well
the
peculiarities
of
ontogenesis.
As
with
all
traits,
lifespan
shows
considerable
variation
within
populations
between
individuals.
Drosophila,
favourite
object
geneticists,
has
greatly
advanced
our
understanding
how
different
forms
variability
affect
lifespan.
This
review
considers
role
heritable
variability,
phenotypic
plasticity
stochastic
in
controlling
Drosophila
melanogaster.
We
discuss
major
historical
milestones
development
approach
to
study
lifespan,
breeding
long-lived
lines,
advances
QTL
mapping,
environmental
that
have
greatest
influence
on
laboratory
maintained
flies,
mechanisms,
by
which
individual
affects
longevity.
The
interplay
approaches
ageing
limitation
will
also
be
discussed.
Particular
attention
paid
interaction
types
control
Insects,
Journal Year:
2020,
Volume and Issue:
11(11), P. 735 - 735
Published: Oct. 27, 2020
The
artificial
introduction
of
the
endosymbiotic
bacterium,
Wolbachia
pipientis,
into
Aedes
(Ae.)
aegypti
mosquitoes
reduces
ability
to
transmit
human
pathogenic
viruses
and
is
now
being
developed
as
a
biocontrol
tool.
Successful
introgression
Wolbachia-carrying
Ae.
native
mosquito
populations
at
field
sites
in
Australia,
Indonesia
Malaysia
has
been
associated
with
reduced
disease
prevalence
treated
community.
In
separate
programs,
also
used
population
suppression
tool,
where
release
male
only
Wolbachia-infected
prevents
from
producing
viable
eggs,
subsequently
suppressing
wild
population.
While
these
technologies
show
great
promise,
they
require
mass
rearing
for
implementation
on
scale
that
not
previously
done.
addition,
induces
some
negative
fitness
effects
aegypti.
differ
depending
strain
present,
one
most
consistent
significant
impacts
shortened
longevity
viability
eggs.
This
review
examines
body
evidence
behind
Wolbachia’s
effect
assesses
nutritional
parasitism
key
cause
considers
how
could
be
overcome
achieve
efficient
large-scale
mosquitoes.
Proceedings of the Royal Society B Biological Sciences,
Journal Year:
2021,
Volume and Issue:
288(1950)
Published: May 5, 2021
The
number
of
offspring
an
organism
can
produce
is
a
key
component
its
evolutionary
fitness
and
life
history.
Here
we
perform
test
the
hypothesized
trade-off
between
size
using
thousands
descriptions
egg-producing
compartments
in
insect
ovary
(ovarioles),
common
proxy
for
potential
insects.
We
find
evidence
negative
relationship
egg
ovariole
when
accounting
adult
body
size.
However,
contrast
to
prior
claims,
note
that
this
not
generalizable
across
all
clades,
highlight
several
factors
may
have
contributed
size-number
being
stated
as
general
rule
previous
studies.
reconstruct
evolution
arrangement
cells
contribute
nutrients
patterning
information
during
oogenesis
(nurse
cells),
show
diversification
both
been
largely
independent
their
presence
or
position
within
ovariole.
Instead,
has
shaped
by
series
transitions
variable
invariant
states,
with
multiple
lineages
evolving
almost
no
variation
number.
implications
these
on
our
understanding
specification
development,
well
importance
considering
developmental
processes
theories
life-history
evolution.
Current Opinion in Insect Science,
Journal Year:
2022,
Volume and Issue:
52, P. 100924 - 100924
Published: April 26, 2022
Most
insects
exhibit
high
reproductive
capacity,
which
demands
large
amounts
of
energy,
including
macronutrients
and
micronutrients.
Interestingly,
many
proteins
involved
in
oogenesis
depend
on
metals
ions,
particular
iron
(Fe),
zinc
(Zn),
copper
(Cu).
Mechanisms
by
metal
ions
influence
reproduction
have
been
described
Drosophila
melanogaster,
but
remain
poorly
understood
hematophagous
where
blood
meals
include
significant
ingestion
ions.
Moreover,
there
is
evidence
that
some
immunity
could
dual
function
both
processes.
This
review
highlights
the
importance
non-hematophagous
insects.
In
addition,
we
discuss
how
optimize
physiological
processes
using
crosstalk
between
physiology
immunity,
a
double-edge
sword
allocating
their
functions
to
protect
insect
ensure
reproduction.
Nature Aging,
Journal Year:
2022,
Volume and Issue:
2(12), P. 1145 - 1158
Published: Dec. 1, 2022
Abstract
Pharmacological
attenuation
of
mTOR
presents
a
promising
route
for
delay
age-related
disease.
Here
we
show
that
treatment
Drosophila
with
the
inhibitor
rapamycin
extends
lifespan
in
females,
but
not
males.
Female-specific,
gut
pathology
is
markedly
slowed
by
treatment,
mediated
increased
autophagy.
Treatment
increases
enterocyte
autophagy
via
H3/H4
histone-Bchs
axis,
whereas
males
high
basal
levels
are
feeding.
Enterocyte
sexual
identity,
determined
transformer
Female
expression,
dictates
sexually
dimorphic
cell
size,
H3/H4-
Bchs
rates
autophagy,
fecundity,
intestinal
homeostasis
and
extension
response
to
rapamycin.
Dimorphism
conserved
mice,
where
intestine,
brown
adipose
tissue
muscle
exhibit
sex
differences
This
study
highlights
as
determining
factor
regulation
metabolic
processes
efficacy
mTOR-targeted,
anti-aging
drug
treatments.
