Silver nanoparticles synthesized from Pseudomonas aeruginosa pyoverdine: Antibiofilm and antivirulence agents

Biofilm, Journal Year: 2024, Volume and Issue: 7, P. 100192 - 100192

Published: March 15, 2024

The increasing incidence of antimicrobial resistance exhibited by biofilm-forming microbial pathogens has been recognized as one the major issues in healthcare sector. In present study, nanomaterial-based controlling biofilm and virulence properties considered an alternative approach. Pyoverdine (PVD) isolated from Pseudomonas aeruginosa was utilized a biological corona to synthesize silver nanoparticles (AgNPs), which will be helpful targeted action due recognition pathogenic membrane. Synthesized PVD-AgNPs were spherical irregular, with average size value 251.87 ± 21.8 nm zeta potential −36.51 0.69 mV. MIC towards P. aeruginosa, Listeria monocytogenes, Staphylococcus aureus, Streptococcus mutans, Escherichia coli, Candida albicans standard host-mimicking media observed decreasing order multi-fold, such growth > sputum synthetic human urine saliva. Both initial stage well-established biofilms these have effectively inhibited eradicated PVD-AgNPs. increase susceptibility tetracycline, PVD, amphotericin B established mature mono- mixed-species S. aureus C. albicans. Additionally, attenuate several properties, inhibition protease activity, motility, PVD pyocyanin production aeruginosa. gene expression virulence-associated genes validates its phenotypic effects.

Language: Английский

---

Bacterial extracellular vesicles: Modulation of biofilm and virulence properties

Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 178, P. 13 - 23

Published: Feb. 27, 2024

Language: Английский

---

Zinc and melatonin mediated antimicrobial, anti-inflammatory, and antioxidant coatings accelerate bone defect repair

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: unknown, P. 114335 - 114335

Published: Oct. 1, 2024

Language: Английский

---

A Critical Review on Sustainable Formulation of Anti-quorum Sensing Compounds Using Nanotechnology Principles Against Candida albicans

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 2, 2025

Language: Английский

---

Nanocomposites against Pseudomonas aeruginosa biofilms: Recent advances, challenges, and future prospects

Microbiological Research, Journal Year: 2024, Volume and Issue: 282, P. 127656 - 127656

Published: Feb. 28, 2024

Language: Английский

---

Strategies for controlling polymicrobial biofilms: a focus on antibiofilm agents

International Journal of Antimicrobial Agents, Journal Year: 2024, Volume and Issue: 64(2), P. 107243 - 107243

Published: June 20, 2024

Language: Английский

---

Artificial Intelligence-Driven Analysis of Antimicrobial-Resistant and Biofilm-Forming Pathogens on Biotic and Abiotic Surfaces

Antibiotics, Journal Year: 2024, Volume and Issue: 13(8), P. 788 - 788

Published: Aug. 22, 2024

The growing threat of antimicrobial-resistant (AMR) pathogens to human health worldwide emphasizes the need for more effective infection control strategies. Bacterial and fungal biofilms pose a major challenge in treating AMR pathogen infections. Biofilms are formed by pathogenic microbes encased extracellular polymeric substances confer protection from antimicrobials host immune system. also promote growth antibiotic-resistant mutants latent persister cells thus complicate therapeutic approaches. ubiquitous cause serious risks due their ability colonize various surfaces, including tissues, medical devices, food-processing equipment. Detection characterization crucial prompt intervention control. To this end, traditional approaches often effective, yet they fail identify microbial species inside biofilms. Recent advances artificial intelligence (AI) have provided new avenues improve biofilm identification. Machine-learning algorithms image-processing techniques shown promise accurate efficient detection biofilm-forming microorganisms on biotic abiotic surfaces. These advancements potential transform research clinical practice allowing faster diagnosis tailored therapy. This comprehensive review focuses application AI identification industries, healthcare, food safety, agriculture. discusses existing approaches, challenges, applications research, with particular focus role improving diagnostic capacities guiding preventative actions. synthesis current knowledge future directions, as described review, will guide development efforts combating biofilm-associated

Language: Английский

---

Attenuation of biofilm and virulence factors of Pseudomonas aeruginosa by tetramethylpyrazine-gold nanoparticles

Microbial Pathogenesis, Journal Year: 2024, Volume and Issue: 191, P. 106658 - 106658

Published: April 20, 2024

Language: Английский

---

Design and development of pH-sensitive nanocarriers using molecularly imprinted polymers for the targeted delivery of sodium thiopental

Nanoscale Advances, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This research introduces the design and synthesis of pH-sensitive MIPs, including magnetic, nonmagnetic, fiber, as targeted nanocarriers for selective uptake controlled release STL molecules in SGF SIF environments.

Language: Английский

---

Editorial for Special Issue " Biomaterial-associated infections: their development, characterization, prevention and treatment” - Colloids and Surfaces B: Biointerfaces

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 251, P. 114594 - 114594

Published: Feb. 23, 2025

Language: Английский

---