Multifunctional Mesoporous Polydopamine Nanoplatforms for Synergistic Photothermal-Chemotherapy and Enhanced Immunotherapy in Breast Cancer Treatment DOI

Siqiong Wu,

Yongjun Chen,

Ke Wang

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 248, P. 114483 - 114483

Published: Dec. 27, 2024

Language: Английский

Preclinical advance in nanoliposome-mediated photothermal therapy in liver cancer DOI Creative Commons
Le Tang, Xiao Yang, Liwen He

et al.

Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 31, 2025

Language: Английский

Citations

2
Advancements in Metal and Metal Oxide Nanoparticles for Targeted Cancer Therapy and Imaging: Mechanisms, Applications, and Safety Concerns DOI Creative Commons
Jameema Sidhic, Aswathi Moothakoottil Kuttithodi, Aparna Prasad

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2025, Volume and Issue: unknown, P. 106622 - 106622

Published: Jan. 1, 2025

Language: Английский

Citations

1
Synergistic combinational photothermal therapy-based approaches for cancer treatment DOI Creative Commons
Gaurisha Alias Resha Ramnath Naik, Ashutosh Gupta, Deepanjan Datta

et al.

FlatChem, Journal Year: 2025, Volume and Issue: unknown, P. 100834 - 100834

Published: Feb. 1, 2025

Language: Английский

Citations

1
Design strategies and applications of cyanine dyes in phototherapy DOI
Jie Yuan, Han‐xue Yang,

Wenhui Huang

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

An overview of cyanine dye-based phototherapy agents, including the design strategies, relationships between molecular structures and properties, as well applications in photodynamic therapy, photothermal multimodal combined therapy.

Language: Английский

Citations

5
The photothermal coupling of TiN@Au core-shell nanorods applied to near-infrared photothermal therapy DOI

Qiuyu Luo,

Yu Liu, Ning Chen

et al.

International Journal of Thermal Sciences, Journal Year: 2024, Volume and Issue: 204, P. 109242 - 109242

Published: July 1, 2024

Language: Английский

Citations

4
Fe-doped biodegradable dendritic mesoporous silica nanoparticles for starvation therapy and photothermal-enhanced cascade catalysis in tumor therapy DOI
Mengwei Ye, Weikang Zhang, Hongwei Xu

et al.

Journal of Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 678, P. 378 - 392

Published: Aug. 24, 2024

Language: Английский

Citations

4
Dissecting the anti-pancreatic cancer mechanism of gold nanorods mediate photothermal therapy through quantitative proteomics analysis DOI

Zhen Sun,

Feng Zhang,

Xin-Yi Liu

et al.

Biochemical and Biophysical Research Communications, Journal Year: 2025, Volume and Issue: 747, P. 151288 - 151288

Published: Jan. 4, 2025

Language: Английский

Citations

0
pH-Responsive Near Infrared Light Triggered Hydroxyapatite Nanoparticles for Targeted Photothermal Cancer Therapy DOI Creative Commons

L. Palanikumar,

Fehmi Sami Yasin,

Itgel Munkhjargal

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 26, 2025

Photothermal therapy (PTT) has emerged as an effective cancer treatment strategy, which utilizes photothermal agents that accumulate at tumor sites and induce localized hyperthermia when irradiated. Near-infrared II (NIR II) fluorophores, such the polymethine cyanine-based dye IR1061, exhibit higher temporal resolution better tissue penetration, thereby making them promising candidates for PTT. However, challenges low water solubility in vivo short circulation times of these dyes limit their biological applications. To address issues, we have developed a biocompatible biodegradable delivery system IR1061 is encapsulated within lipid-coated hydroxyapatite nanoparticles (LHAPNIRs). The lipid shell composed DPPC/cholesterol/DSPE-PEG to retain prevent serum protein adsorption macrophage recognition, would otherwise hinder targeting. Finally, coat functionalized with acidity-triggered rational membrane (ATRAM) peptide efficient specific internalization into cells mildly acidic microenvironment characteristic tumors. facilitated real-time thermal imaging showed potent NIR-light triggered anticancer activity vitro , no noticeable toxicity healthy tissue. Our results demonstrate ATRAM-LHAPNIRs (ALHAPNIRs) combine PTT robust diagnostic capabilities.

Language: Английский

Citations

0
Anti-Tumor Strategies of Photothermal Therapy Combined with Other Therapies Using Nanoplatforms DOI Creative Commons

Rubing Xu,

Shengmei Wang,

Qiuyan Guo

et al.

Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(3), P. 306 - 306

Published: Feb. 26, 2025

Conventional cancer treatments often have complications and serious side effects, with limited improvements in 5-year survival quality of life. Photothermal therapy (PTT) employs materials that convert light to heat when exposed near-infrared raise the temperature tumor site directly ablate cells, induce immunogenic cell death, improve microenvironment. This has several benefits, including minimal invasiveness, high efficacy, reduced robust targeting capabilities. Beyond just photothermal conversion materials, nanoplatforms significantly contribute PTT by supplying effective bolstering amplify anti-tumor effects. However, effects alone are ultimately need be combined other therapies. narrative review describes recent progress chemotherapy, radiotherapy, photodynamic therapy, immunotherapy, gene gas chemodynamic photoacoustic imaging, starvation multimodal therapy. Studies shown combining can reduce overcome drug resistance. Despite encouraging results, challenges such as optimizing treatment protocols, addressing heterogeneity, overcoming biological barriers remain. paper highlights potential for personalized, approaches outcomes.

Language: Английский

Citations

0
Structural Modification of Heptamethine Indocyanine Dyes with Improved Aqueous Solubility and Stability for Photothermal Therapy DOI

Xinyi Shen,

Jing Yu,

Tingyan Chen

et al.

European Journal of Medicinal Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 117532 - 117532

Published: March 1, 2025

Language: Английский

Citations

0