Multifunctional Carbon Dots Inhibit the Amyloid Fibrillation and Scavenge Free Radicals DOI
Dexin Li,

Xinnan Wang,

Sibo Wang

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: unknown, P. 141134 - 141134

Published: Dec. 1, 2024

Language: Английский

Quercetin-functionalized nanomaterials: Innovative therapeutic avenues for Alzheimer's disease management DOI
Jinjin Pei,

Ranil Vikraman Kumarasamy,

Selvaraj Jayaraman

et al.

Ageing Research Reviews, Journal Year: 2025, Volume and Issue: unknown, P. 102665 - 102665

Published: Jan. 1, 2025

Language: Английский

Citations

11
Biological Waste-Derived Carbon Dots and Their Applications DOI
Subhamoy Banerjee, Ruchira Mukherjee

Nanostructure science and technology, Journal Year: 2025, Volume and Issue: unknown, P. 107 - 128

Published: Jan. 1, 2025

Language: Английский

Citations

0
Disruption of fibrillar assemblies of L-Phenylalanine using polyphenol passivated nanocarbon as potential therapeutic strategy against Phenylketonuria DOI
Subir Chatterjee, Krishan Kumar,

Piyush Kumar

et al.

Organic & Biomolecular Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Polyphenol passivated nanocarbon system with potential to disrupt and inhibit the fibrillar assemblies of aromatic amino acid l -phenylalanine at pathological concentrations.

Language: Английский

Citations

0
QUERCETIN-DERIVED CARBON DOTS PROMOTE PROLIFERATION AND MIGRATION OF SCHWANN CELLS AND ENHANCE NEURITE OUTGROWTH. DOI Creative Commons

Phanindra Babu Kasi,

Henry Opoku,

Liudmila N. Novikova

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 251, P. 114609 - 114609

Published: March 7, 2025

Quercetin, a flavonoid known for its antioxidant properties, has recently garnered attention as potential neuroprotective agent treatment of the injured nervous system. The repair peripheral nerve injuries hinges on proliferation and migration Schwann cells, which play crucial role in supporting axonal growth myelination. In this study we synthesized Quercetin-derived carbon dots (QCDs) investigated their effects cultured cells NG108-15 cell line. QCDs was obtained by solvothermal synthesis characterized via UV-vis absorption spectroscopy, transmission electron microscopy, Fourier transform infrared X-ray diffraction analysis. particles demonstrated significant dose-dependent free radical scavenging activity DPPH ABTS assays, supported vitro expression neurotrophic angiogenic factors, stimulated neurite outgrowth from cells. Thus, could serve novel strategy to promote regeneration

Language: Английский

Citations

0
Cerium-doped carbon dots as dual-target agents against Alzheimer's β-amyloid fibrillogenesis and reactive oxygen species DOI
Wenjuan Wang, Zhaoyu Liu,

Hao Cheng

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: unknown, P. 114655 - 114655

Published: March 1, 2025

Language: Английский

Citations

0
Dual‐Carbon Dots Composite: A Multifunctional Photo‐Propelled Nanomotor Against Alzheimer's β‐Amyloid DOI Open Access
Xiaoding Lin, Xiaoyan Dong, Yan Sun

et al.

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 11, 2024

Abstract The abnormal accumulation of β ‐amyloid protein (A ) is considered as the main pathological hallmark Alzheimer's disease (AD). design potent multifunctional theranostic agents targeting A one effective strategies for AD prevention and treatment. Nanomotors intelligent, advanced, nanoplatforms can perform many complex tasks, but their application in theranostics rare. Herein, sub‐10nm dual‐carbon dots composites (ERCD) with photo‐propelled nanomotor behavior are fabricated by conjugating near‐infrared (NIR) carbon (RCD) thermogenic photodynamic capability previously reported epigallocatechin gallate‐derived carbonized polymer (ECD). ERCD‐1 (ECD:RCD = 1:2.5) showed inhibitory similar to ECD absence NIR light, exhibited photooxygenation activity powered “self‐thermophoretic force” under irradiation, significantly enhancing inhibition, disaggregation, capabilities. suppressed fibrillization rapidly disaggregated mature fibrils at very low concentrations (0.5 µg mL −1 ). Moreover, NIR‐activated imaged plaques vivo prolonged nematode lifespan 6 d 2 . As a proof‐of‐concept, this work opened new avenue nanomotors theranostics.

Language: Английский

Citations

3
Application of carbon dots-based nanomaterials in amyloid aggregation disease DOI
Chaoren Yan, Xu Shao,

Yixuan Wang

et al.

Carbon, Journal Year: 2024, Volume and Issue: unknown, P. 119971 - 119971

Published: Dec. 1, 2024

Language: Английский

Citations

1
Carbonized Polymer Dots: Influence of the Carbon Nanoparticle Structure on Cell Biocompatibility DOI Creative Commons

Mayara Martins Caetano,

Amanda Blanque Becceneri, Marcos V. Ferreira

et al.

ACS Omega, Journal Year: 2024, Volume and Issue: 9(37), P. 38864 - 38877

Published: Sept. 5, 2024

Carbonized polymer dots (CPDs) were obtained by using microwave irradiation under the same conditions. However, different carbogenic precursors used, such as aromatic diamine molecules,

Language: Английский

Citations

0
Vitamin C derived carbon dots: inhibiting amyloid aggregation and scavenging reactive oxygen species DOI

Tiange Fan,

Xiuyun Cao, Chao Wang

et al.

New Journal of Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 12, 2024

The pathogenesis of Alzheimer's disease is very complex, so its multifunctional treatment great significance, in which the synergistic therapy amyloid cascade hypothesis and oxidative stress shows good results.

Language: Английский

Citations

0
Multifunctional Carbon Dots Inhibit the Amyloid Fibrillation and Scavenge Free Radicals DOI
Dexin Li,

Xinnan Wang,

Sibo Wang

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: unknown, P. 141134 - 141134

Published: Dec. 1, 2024

Language: Английский

Citations

0