Recent Advances in Bioactive Peptides as Functional Food for Health Promotions and Medicinal Applications DOI

P. J. Sreelekshmi,

V. Devika,

Lakshmi Satheesh Aiswarya

et al.

Protein and Peptide Letters, Journal Year: 2023, Volume and Issue: 30(8), P. 626 - 639

Published: July 7, 2023

Bioactive peptides obtained from natural resources are useful due to their ability prevent the risk of dreadful conditions such as hypertension, cancers, obesity and cardiovascular diseases. Proteins food, plants, animals dairy products chemically or enzymatically hydrolyzed fermented in presence microbes produce bioactive peptides. antioxidant, antihypertensive, anti-inflammatory, antiproliferative, antibacterial, anticancer, antimicrobial some them also show multiple bioactivities. Also, offer much potential nutraceuticals functional food components. This paper reviews recent progress (2020-2022) on derived animals, products. Emphasis is given production, purification, use for health promotions medicinal applications.

Language: Английский

Antimicrobial plant-derived peptides obtained by enzymatic hydrolysis and fermentation as components to improve current food systems DOI Creative Commons
Fernando Rivero‐Pino, María José León, María C. Millán-Linares

et al.

Trends in Food Science & Technology, Journal Year: 2023, Volume and Issue: 135, P. 32 - 42

Published: March 6, 2023

New challenges in our society are appearing following the emergence of antibiotic-resistant microorganisms and concerns about use antibiotics. Furthermore, food spoilage due to leads waste around 1.3 billion tons each year. Bioactive peptides obtained from proteins, released by enzymatic hydrolysis or fermentation, can be employed as a natural alternative antibiotics preservative agents, their ability inhibit growth several microorganisms. Plant protein industry is increasing over animal protein, environmental welfare population. Considering antibiotics, exploitation source antimicrobial gaining interest recent years. This review aims summarize published literature on hydrolysates peptides, fermentation plants, mechanisms, producing fortified products edible coatings. Antibacterial antifungal plant studied larger extent that antiviral but further research concerning identification applicability must done. The results show promising uses many areas such fortification foods active packaging with dual bioactivity, related activity – avoiding resistance.

Language: Английский

Citations

42

Deep learning drives efficient discovery of novel antihypertensive peptides from soybean protein isolate DOI
Yiyun Zhang, Zijian Dai, Xinjie Zhao

et al.

Food Chemistry, Journal Year: 2022, Volume and Issue: 404, P. 134690 - 134690

Published: Oct. 20, 2022

Language: Английский

Citations

29

Effects of fungal based bioactive compounds on human health: Review paper DOI Creative Commons
Neda Rousta, Melissa Aslan, Meltem Yeşilçimen Akbaş

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2023, Volume and Issue: 64(20), P. 7004 - 7027

Published: Feb. 15, 2023

Since the first years of history, microbial fermentation products such as bread, wine, yogurt and vinegar have always been noteworthy regarding their nutritional health effects. Similarly, mushrooms a valuable food product in point both nutrition medicine due to rich chemical components. Alternatively, filamentous fungi, which can be easier produce, play an active role synthesis some bioactive compounds, are also important for health, well being protein content. Therefore, this review presents compounds (bioactive peptides, chitin/chitosan, β-glucan, gamma-aminobutyric acid, L-carnitine, ergosterol fructooligosaccharides) synthesized by fungal strains benefits. In addition, potential probiotic- prebiotic fungi were researched determine effects on gut microbiota. The current uses based cancer treatment discussed. use industry, especially develop innovative production, has seen promising microorganisms obtaining healthy nutritious food.

Language: Английский

Citations

21

Recent advances in exploring and exploiting soybean functional peptides—a review DOI Creative Commons
Yongsheng Zhu, Gang Chen, Jingjing Diao

et al.

Frontiers in Nutrition, Journal Year: 2023, Volume and Issue: 10

Published: June 15, 2023

Soybeans are rich in proteins and phytochemicals such as isoflavones phenolic compounds. It is an excellent source of peptides with numerous biological functions, including anti-inflammatory, anticancer, antidiabetic activities. Soy bioactive small building blocks that released after fermentation or gastrointestinal digestion well by food processing through enzymatic hydrolysis, often combination novel techniques (i.e., microwave, ultrasound, high-pressure homogenization), which associated health benefits. Various studies have reported the potential benefits soybean-derived functional peptides, made them a great substitute for many chemical-based elements foods pharmaceutical products healthy lifestyle. This review provides unprecedented up-to-date insights into role soybean various diseases metabolic disorders, ranging from diabetes hypertension to neurodegenerative disorders viral infections mechanisms were discussed. In addition, we discuss all known techniques, conventional emerging approaches, prediction active peptides. Finally, real-life applications entities

Language: Английский

Citations

19

Preparation, characterization and functional properties of ternary composite nanoparticles for enhanced water solubility and bioaccessibility of lutein DOI
Xiaojing Du, Shan Wang,

Zaixiang Lou

et al.

Food Hydrocolloids, Journal Year: 2023, Volume and Issue: 144, P. 109039 - 109039

Published: July 7, 2023

Language: Английский

Citations

19

Introducing Bacillus natto and Propionibacterium shermanii into soymilk fermentation: A promising strategy for quality improvement and bioactive peptide production during in vitro digestion DOI
Xiaohui Wu,

Honghong Liu,

Junqing Han

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 455, P. 139585 - 139585

Published: June 5, 2024

Language: Английский

Citations

6

In silico analysis of angiotensin-converting enzyme inhibitory compounds obtained from soybean [Glycine max (L.) Merr.] DOI Creative Commons
Ayyagari Ramlal, Isha Bhat,

Aparna Nautiyal

et al.

Frontiers in Physiology, Journal Year: 2023, Volume and Issue: 14

Published: May 31, 2023

Cardiovascular diseases (CVDs) are one of the major reasons for deaths globally. The renin–angiotensin–aldosterone system (RAAS) regulates body hypertension and fluid balance which causes CVD. Angiotensin-converting enzyme I (ACE I) is central Zn-metallopeptidase component RAAS playing a crucial role in maintaining homeostasis cardiovascular system. available drugs to treat CVD have many side effects, thus, there need explore phytocompounds peptides be utilized as alternative therapies. Soybean unique legume cum oilseed crop with an enriched source proteins. extracts serve primary ingredient drug formulations against diabetes, obesity, spinal cord-related disorders. Soy proteins their products act ACE may provide new scope identification potential scaffolds that can help design safer natural In this study, molecular basis selective inhibition 34 soy phytomolecules (especially beta-sitosterol, soyasaponin I, II, II methyl ester, dehydrosoyasaponin phytic acid) was evaluated using silico docking approaches dynamic simulations. Our results indicate amongst compounds, beta-sitosterol exhibited inhibitory action I.

Language: Английский

Citations

14

Investigating Bambara bean (Vigna subterranea (Verdc.) L.) protein and hydrolysates: a comprehensive analysis of biological and biochemical properties DOI Creative Commons
Mamoudou Hamadou, Martin Alain Mune Mune

Applied Food Research, Journal Year: 2024, Volume and Issue: 4(2), P. 100489 - 100489

Published: Aug. 30, 2024

Language: Английский

Citations

5

Ultrasonication for production of nanoliposomes with encapsulated soy protein concentrate hydrolysate: Process optimization, vesicle characteristics and in vitro digestion DOI Creative Commons
Neda Pavlović, Jelena Mijalković, Verica Đorđević

et al.

Food Chemistry X, Journal Year: 2022, Volume and Issue: 15, P. 100370 - 100370

Published: June 18, 2022

This study presents the state-of-art research about assembly of soy proteins in nanocarriers, liposomes, and its design includes different physicochemical strategies approaches: two-step enzymatic hydrolysis concentrate, hydrolysate encapsulation by using phospholipids cholesterol, application ultrasonication. Achieved results revealed that ultrasonication, together with cholesterol addition into phospholipid layers, improved stability nanoliposomes, a maximum EE value 60.5 % was obtained. Average size peptide-loaded nanoliposomes found to be from 191.1 286.7 nm, ζ potential -25.5 -34.6 mV, polydispersity index 0.250-0.390. Ultrasound-assisted process did not lead decrease antioxidant activity trapped peptides. FTIR has indicated an effective hydrophobic interaction between phosphatidylcholine TEM SEM have confirmed spherical nanocarrier structure unilamelarity. Prolonged gastrointestinal release peptides been enabled liposome nanocarriers.

Language: Английский

Citations

20

Lunasin, soluble protein concentration and profile in Glycine soja compared to Glycine max, bioaccessibility and peptides bioactivity DOI
Jennifer Kusumah,

Javier Aguado Preciado,

Jiazheng Yuan

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106370 - 106370

Published: March 1, 2025

Language: Английский

Citations

0