2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation, Journal Year: 2024, Volume and Issue: 149(8)

Published: Jan. 24, 2024

BACKGROUND: The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep, obesity) factors (cholesterol, blood pressure, glucose control, metabolic syndrome) that contribute health. AHA Disease Stroke Statistical Update presents latest data on a range major clinical circulatory disease conditions (including brain health, complications pregnancy, kidney congenital rhythm disorders, sudden cardiac arrest, subclinical atherosclerosis, coronary cardiomyopathy, failure, valvular venous thromboembolism, peripheral artery disease) associated outcomes quality care, procedures, economic costs). METHODS: AHA, through its Epidemiology Prevention Statistics Committee, continuously monitors evaluates sources stroke United States globally provide current information available annual review published literature year before writing. 2024 is product full year’s worth effort 2023 by dedicated volunteer clinicians scientists, committed government professionals, staff members. strives further understand help heal problems inflicted structural racism, public crisis can significantly damage mental perpetuate disparities access education, income, housing, several other vital healthy lives. This edition includes additional global data, as well monitoring benefits population, an enhanced focus equity across key domains. RESULTS: Each chapters focuses different topic statistics. CONCLUSIONS: represents critical resource for lay public, policymakers, media clinicians, care administrators, researchers, advocates, others seeking best these conditions.

Language: Английский

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Relation of Life’s Essential 8 to the genetic predisposition for cardiovascular outcomes and all-cause mortality: results from a national prospective cohort

European Journal of Preventive Cardiology, Journal Year: 2023, Volume and Issue: 30(15), P. 1676 - 1685

Published: May 25, 2023

Abstract Aims To evaluate the independent, mediating, interactive, and associated effects of Life's Essential 8 (LE8) genetic predisposition on risk cardiovascular outcomes all-cause mortality. Methods results We retrieved a total 254 783 individuals from UK Biobank. LE8 was determined by eight metrics (nicotine exposure, physical activity, diet, sleep, body mass index, blood pressure, glucose, lipids), characterized as low, moderate, high health (CVH). Genetic estimated using polygenic score (PRS). Cox regressions were performed to associations between LE8, PRS, outcomes. During median follow-up 12.53 years, mortality occurred in 10 257 197 473 participants, 2074 215 675, incident disease (CVD) 71 774 675. Individuals with moderate or CVH experienced lower [hazard ratios (HRs) 0.33 0.81] adverse compared their counterparts low CVH. A substantial proportion (16.1∼69.8%) could be attributable up 51.2% PRS mediated LE8. In group, had CVD (HR: 0.26, 95% confidence interval: 0.18, 0.39), those Conclusion Ideal risks mortality, more pronounced association observed for CVD. Improving according guidelines should encouraged, especially that indicate risk.

Language: Английский

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Life’s Essential 8 and Mortality in US Adults with Chronic Kidney Disease

American Journal of Nephrology, Journal Year: 2023, Volume and Issue: 54(11-12), P. 516 - 527

Published: Jan. 1, 2023

<b><i>Introduction:</i></b> The current prevalence of chronic kidney disease (CKD) is substantial, and CKD individuals face a heightened risk mortality, encompassing both all-cause cause-specific outcomes. study aims to investigate the potential impact adhering Life’s Essential 8 (LE8) on reducing mortality among individuals. <b><i>Methods:</i></b> Using National Health Nutrition Survey (NHANES) data from 2005 2018, we analyzed 22,420 US adults (≥20 years old). defined by urinary albumin-to-creatinine ratio (≥30 mg/g or 3 mg/mmol) estimated glomerular filtration rate (&lt;60 mL/min/1.73 m²). components LE8, including diet, physical activity (PA), nicotine exposure, sleep, body mass index, blood lipids, glucose, pressure (BP), were measured given score 0–100. total LE8 was unweighted average all divided into low cardiovascular health (CVH) (0–49), moderate CVH (50–79), high (80–100). A Cox proportional hazards regression model used explore associations with all-cause, (CVD), cancer which followed prospectively Center for Statistics until December 31, 2019. <b><i>Results:</i></b> In overall population, had 47% lower CKD, while linked 55% compared CVH. During median follow-up 7.58 years, 93% higher 149% CVD those without CKD. Among individuals, every 10-point increase in associated reduced risks 17% (especially PA, BP), 18% PA), 12% PA sleep health). additional sensitivity analysis, results remained significant after further consideration confounding renal function. Additionally, demonstrated superior stratification patients LS7. Interaction observed between age, education level, marital status, drinking status. <b><i>Conclusion:</i></b> demonstrates that adherence levels within mortality.

Language: Английский

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Association of Life's Essential 8 With Cardiovascular Disease and Mortality: The Framingham Heart Study

Journal of the American Heart Association, Journal Year: 2023, Volume and Issue: 12(23)

Published: Nov. 28, 2023

Background The association of the American Heart Association's updated cardiovascular health score, Life's Essential 8 (LE8), with disease (CVD) and death is not described in FHS (Framingham Study). Methods Results We evaluated Framingham Offspring participants at examinations 2 6 (n=2888 1667; mean age, 44 57 years, respectively), free CVD information on LE8 components. Using age‐sex–adjusted Cox models, we related its change (examination to examination 6) risk compared associations those Simple 7 score. Mean score was 67 points (minimum, 26 points; maximum, 100 points). At both examinations, were reclassified a different status, depending which method (LE8 versus 7) used (60% ideal status intermediate category). On follow‐up after (median, 30 33 years for death, observed 966 events, 1195 died. Participants having LE8≥68 (sample median) lower LE8<68 2: hazard ratio [HR], 0.47 [95% CI, 0.41–0.54]; HR, 0.55 0.49–0.62]; all P <0.001). maintaining low scores during life course highest (CVD: HRs ranging from 1.8 2.3; <0.001; 1.45 1.13–1.85]; =0.003 high‐high group). Conclusions Further studies are warranted elucidate whether better marker risk,

Language: Английский

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“Life's Essential 8” Cardiovascular Health and Dementia Risk, Cognition, and Neuroimaging Markers of Brain Health

Journal of the American Medical Directors Association, Journal Year: 2023, Volume and Issue: 24(11), P. 1791 - 1797

Published: June 24, 2023

Language: Английский

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Association between life’s essential 8 and periodontitis: a population-based study

BMC Oral Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 4, 2024

Abstract Background The American Heart Association has developed a novel cardiovascular health indicator called Life’s Essential 8 (LE8). However, no one reported using LE8 to assess periodontitis. This study aimed investigate the association between and periodontitis in adults. Methods Data from National Health Nutrition Examination Survey (NHANES) 2009 2014 were used for this investigation. was independent variable, it is divided into three grades: high, moderate, low. Periodontitis dependent classification of based on criteria Eke 2012. Multivariable logistic regression models explore relationship Results A total 9,039 participants with an average age 52.16 ± 14.21 years enrolled study, whom 48.29% male 51.71% female. mean standard deviation 66.29 14.57, prevalence 50.48% overall. score fully adjusted model showed negative correlation (OR = 0.98; 95% CI, 0.98–0.99, p < 0.001). result persisted when categorized low, high groups. Compared those lowest group, highest group had 47% decreased risk 0.53; 0.46–0.66, P Conclusions cross-sectional investigation revealed likelihood

Language: Английский

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THE ROLE OF EDUCATION AND INFORMATION TO PREVENT TRENDS TOWARDS INCREASE OF CARDIOVASCULAR MORTALITY RATES IN EUROPE FROM 2015 TO 2019.

Current Problems in Cardiology, Journal Year: 2024, Volume and Issue: 49(3), P. 102415 - 102415

Published: Jan. 20, 2024

Language: Английский

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How Diet and Lifestyle Can Fine-Tune Gut Microbiomes for Healthy Aging

Annual Review of Food Science and Technology, Journal Year: 2024, Volume and Issue: 15(1), P. 283 - 305

Published: June 28, 2024

Many physical, social, and psychological changes occur during aging that raise the risk of developing chronic diseases, frailty, dependency. These adversely affect gut microbiota, a phenomenon known as microbe-aging. Those microbiota alterations are, in turn, associated with development age-related diseases. The is highly responsive to lifestyle dietary changes, displaying flexibility also provides anactionable tool by which healthy can be promoted. This review covers, firstly, main socioeconomic factors modify composition function or unhealthy and, secondly, advances being made defining promoting aging, including microbiome-informed artificial intelligence tools, personalized patterns, food probiotic systems.

Language: Английский

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Comparative Discrimination of Life’s Simple 7 and Life’s Essential 8 to Stratify Cardiovascular Risk: Is the Added Complexity Worth It?

Circulation, Journal Year: 2023, Volume and Issue: 149(12), P. 905 - 913

Published: Oct. 13, 2023

Life's Simple 7 (LS7) is an easily calculated and interpreted metric of cardiovascular health based on domains: smoking, diet, physical activity, body mass index, blood pressure, cholesterol, fasting glucose. The Essential 8 (LE8) was subsequently introduced, adding sleep metrics revisions the previous domains. Although calculating LE8 requires additional information, we hypothesized that it would be a more reliable index health.

Language: Английский

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Association Between the AHA Life's Essential 8 Score and Incident All-Cause Dementia: A Prospective Cohort Study from UK Biobank

Current Problems in Cardiology, Journal Year: 2023, Volume and Issue: 48(11), P. 101934 - 101934

Published: July 7, 2023

This study aimed to investigate the association between LE8 score and incident all-cause dementia (including Alzheimer's disease [AD] vascular dementia) in UK Biobank. 259,718 participants were included this prospective study. Smoking, non-HDL cholesterol, blood pressure, body mass index, HbA1c, physical activity, diet, sleep used create score. Associations (both continuous as quartiles) outcomes investigated using adjusted linear nonlinear Cox proportional hazard models. The potential impact fractions of two scenarios rate advancement periods also calculated. Over a median follow-up 10.6 years, 4,958 diagnosed with any dementia. Higher scores associated lower risk an exponential decay pattern. Compared individuals healthiest quartile, those least healthy quartile had higher (HR: 1.50 [95% CI: 1.37 1.65] 1.86 [1.44 2.42]). A targeted intervention that increased, by 10-points, among lowest could have prevented 6.8% cases. Individuals might develop 2.45 years earlier than their counterparts. Because associations, interventions at produce greater population-level benefits.

Language: Английский

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