Journal of the American Heart Association,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 20, 2024
Background
We
evaluated
the
effects
of
a
national
school‐based
lifestyle
intervention
program
against
childhood
obesity
on
improving
cardiovascular
health
(CVH),
assessed
using
recently
introduced
Life's
Essential
8
metric
framework.
Methods
and
Results
Our
post
hoc
analysis
targeting
diet
physical
activity
included
94
schools
with
eligible
students
aged
7
to
17
years
(intervention
group
n=30
629;
control
n=26
581).
CVH
metrics
by
individual
scores
for
4
behaviors
(diet,
activity,
nicotine
exposure,
body
mass
index)
3
factors
(blood
lipids,
glucose,
pressure).
These
were
subsequently
combined
calculate
score,
behavior
factor
score.
The
primary
outcomes
these
composite
high
(CVH
score≥80).
All
analyses
applied
likelihood‐based
random‐effects
regression
modeling
following
intention‐to‐treat.
was
associated
0.89‐point
increase
in
score
(95%
CI,
0.03–1.74),
14%
greater
odds
having
(odds
ratio,
1.14
[95%
1.01–1.29]),
1.35‐point
improvement
0.32–2.38).
According
our
subgroup
analyses,
this
had
stronger
favorable
(grades
1–6)
junior
7–9)
than
senior
10–12)
(
P
<0.001).
Conclusions
This
improved
Chinese
children
adolescents.
differences
effect
according
school
grade
imply
critical
windows
forming
healthy
lifestyles
at
younger
ages.
Registration
URL:
https://www.clinicaltrials.gov
;
Unique
identifier:
NCT02343588.
Circulation Cardiovascular Quality and Outcomes,
Journal Year:
2024,
Volume and Issue:
17(5)
Published: April 19, 2024
The
American
Heart
Association
recently
launched
updated
cardiovascular
health
metrics,
termed
Life's
Essential
8
(LE8).
Compared
with
Simple
7
(LS7),
the
new
approach
added
sleep
as
an
eighth
metric
and
remaining
factors
behaviors.
association
of
LE8
score
long-term
disease
(CVD)
outcomes
death
is
unknown.
Journal of Stroke and Cerebrovascular Diseases,
Journal Year:
2025,
Volume and Issue:
34(3), P. 108238 - 108238
Published: Jan. 12, 2025
This
study
aims
to
explore
the
association
between
Life's
Essential
8
(LE8)
and
stroke
all-cause
mortality,
compare
whether
it
has
an
advantage
over
Simple
7
(LS7).
investigated
data
from
NHANES
spanning
1999
2018.
The
LE8
was
categorized
as
low,
moderate
high
cardiovascular
health
(CVH).
LS7
score
inadequate,
average,
or
optimal.
Weighted
logistic
regression
restricted
cubic
spline
(RCS)
were
used
examin
correlations.
Receiver
operating
characteristic
(ROC)
curves
employed
detect
accuracy
in
predicting
stroke.
stratified
sensitivity
analyses
conducted
along
with
mediation
analysis.
In
addition,
a
longitudinal
cohort
constructed
by
combining
mortality
data,
Cox
models
utilized
determine
CVH
rate.
For
LE8,
compared
low
CVH,
associated
41%
lower
risk
of
stroke,
71%
prevalence
LS7,
inadequate
average
24%
optimal
39%
RCS
showed
inverse
dose-response
relationships
both
unweighted
ROC,
(AUC=0.702,
95%
CI:
0.685-0.718,
P<0.001)
stronger
ability
discriminate
than
(0.677,
0.658-0.696,
(PDeLong=0.046).
Sensitivity
demonstrated
robustness
GGT
WBC
mediated
4.92%
4.58%
association,
respectively.
neither
nor
predictive
among
survivor.
outperformed
classifying
Oxidative
stress
inflammation
World Journal of Hepatology,
Journal Year:
2025,
Volume and Issue:
17(2)
Published: Feb. 20, 2025
BACKGROUND
Cardiovascular
health
(CVH)
plays
a
crucial
role
in
overall
health,
but
its
association
with
metabolic-associated
fatty
liver
disease
(MAFLD)
remains
unclear.
AIM
To
investigate
the
relationship
between
CVH,
measured
using
Life’s
Essential
8
(LE8)
and
Simple
7
(LS7),
prevalence
of
MAFLD.
METHODS
This
cross-sectional
study
had
sample
2234
individuals,
representing
approximately
120
million
individuals
United
States.
Baseline
parameters
were
compared
LE8
LS7
groups.
Logistic
regression
models
used
to
evaluate
LE8,
LS7,
MAFLD,
while
taking
into
account
confounding
factors.
The
investigation
employed
restricted
cubic
splines
non-linear
associations.
Subgroup
analyses
sensitivity
studies
performed
strength
reliability
results.
RESULTS
Higher
scores
significantly
associated
decreased
risk
even
after
controlling
for
demographic,
socioeconomic,
clinical
variables.
demonstrated
pattern,
most
dramatic
reduction
observed
at
higher
CVH
levels.
Individual
components,
notably
healthy
behaviors
factors,
exhibited
strong
relationships
indicated
consistent
across
several
demographics.
Sensitivity
tests
utilizing
other
MAFLD
definitions
validated
robustness
findings.
CONCLUSION
adherence
criteria,
as
by
scores,
is
lower
These
results
emphasize
need
advance
control
avoid
Neurology,
Journal Year:
2024,
Volume and Issue:
103(8)
Published: Sept. 18, 2024
Diet
may
influence
the
development
of
cognitive
impairment
and
affect
decline,
but
whether
this
relationship
varies
between
Black
American
White
people
is
unclear.
This
study
examined
association
Mediterranean-Dietary
Approaches
to
Stop
Hypertension
Intervention
for
Neurodegenerative
Delay
(MIND)
incident
trajectories
in
a
biracial
prospective
cohort
study.
Discover Food,
Journal Year:
2025,
Volume and Issue:
5(1)
Published: Jan. 11, 2025
Hypertension
(HT)
significantly
impacts
cardiovascular
health
(CVH)
by
exerting
chronic
stress
on
arteries
and
the
heart,
leading
to
severe
complications.
This
review
explores
intricate
relationship
between
dietary
choices
high
blood
pressure
(BP).
Dietary
are
crucial
in
both
development
management
of
BP.
Excessive
sodium
intake
is
a
well-documented
risk
factor
for
HT,
strategies
reduce
salt
consumption
can
mitigate
its
adverse
effects.
Processed
packaged
foods
also
pose
risks
due
hidden
other
unhealthy
ingredients,
making
healthier
alternatives
essential.
Potassium
plays
vital
role
managing
BP,
with
potassium-rich
supporting
balanced
diet.
Saturated
trans
fats
contribute
elevated
fat
recommended.
sugar
negatively
affects
sugars
popular
requiring
practical
reduction.
Alcohol
caffeine
influence
moderate
advised
avoid
potential
risks.
The
Mediterranean
diet
offers
holistic,
evidence-based
approach
enhancing
CVH,
advice
meal
plans
flavourful
health-promoting
regimen.
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(2), P. 626 - 626
Published: Jan. 19, 2025
A
healthy
lifestyle
plays
a
key
role
for
maintaining
the
cardiovascular
health
(CVH)
status
and
prevent
disease
occurrence.
In
fact,
was
included
in
AHA
Cardiovascular
Health
score
(Life’s
Simple
7
[LS7]),
subsequently
updated
to
Life’s
8
[LS8].
Apart
from
importance
of
controlling
conventional
risk
factors,
increasing
evidence
supports
contributory
hormones.
Higher
levels
natriuretic
peptides
(NPs)
lower
renin
aldosterone
were
significantly
associated
CVH.
NT-proBNP
showed
direct
relationship
with
CVH
scores
large
general
Caucasian
populations,
being
also
marker
changes
predictor
future
adverse
events.
On
other
hand,
inversely
related
scores.
contrast,
counter-regulatory
angiotensins
[Ang
(1-7)
acting
through
Mas
receptor,
Ang
(1-9)
Angiotensin
Type
2
alamandine]
strengthen
beneficial
properties
NPs.
This
can
be
explained
by
both
effects
on
systemic
hemodynamic
possible
pleiotropic
local
functions
regulating
different
pathways
involved
maintenance
Based
current
evidence,
circulating
NT-proBNP,
may
affect
apparently
asymptomatic
individuals
represent
additional
markers
residual
risk.
