Lemongrass Essential Oil Components with Antimicrobial and Anticancer Activities

Antioxidants, Journal Year: 2021, Volume and Issue: 11(1), P. 20 - 20

Published: Dec. 22, 2021

The prominent cultivation of lemongrass (Cymbopogon spp.) relies on the pharmacological incentives its essential oil. Lemongrass oil (LEO) carries a significant amount numerous bioactive compounds, such as citral (mixture geranial and neral), isoneral, isogeranial, geraniol, geranyl acetate, citronellal, citronellol, germacrene-D, elemol, in addition to other compounds. These components confer various actions LEO, including antifungal, antibacterial, antiviral, anticancer, antioxidant properties. LEO attributes are commercially exploited pharmaceutical, cosmetics, food preservations industries. Furthermore, application treatment cancer opens new vista field therapeutics. Although different have shown promising anticancer activities vitro, their effects not yet been assessed human system. Hence, further studies mechanisms conferred by required. present review intends provide timely discussion relevance combating sustaining healthcare, well industry applications.

Language: Английский

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Humidity sensors that alert mosquitoes to nearby hosts and egg-laying sites

Neuron, Journal Year: 2023, Volume and Issue: 111(6), P. 874 - 887.e8

Published: Jan. 13, 2023

Language: Английский

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Drosophilasensory receptors—a set of molecular Swiss Army Knives

Genetics, Journal Year: 2021, Volume and Issue: 217(1), P. 1 - 34

Published: Jan. 1, 2021

Genetic approaches in the fruit fly, Drosophila melanogaster, have led to a major triumph field of sensory biology-the discovery multiple large families receptors and channels. Some these families, such as transient receptor potential channels, are conserved from animals ranging worms humans, while others, "gustatory receptors," "olfactory "ionotropic restricted invertebrates. Prior identification flies, it was widely assumed that proteins function just one modality vision, smell, taste, hearing, somatosensation, which includes thermosensation, light, noxious mechanical touch. By employing vast combination genetic, behavioral, electrophysiological, other concept emerge is many multitaskers. The earliest example this idea individual channels senses. It now clear multitasking exhibited by including gustatory receptors, ionotropic epithelial Na+ (also referred Pickpockets), even opsins, were formerly thought exclusively light sensors. characterizations neurons express them also reveal mechanisms through flies can accurately differentiate between different stimuli when they activate same receptor, well adaptation, amplification, integration. insights gleaned studies been highly influential directing investigations animal models.

Language: Английский

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The ion channel ppk301 controls freshwater egg-laying in the mosquito Aedes aegypti

eLife, Journal Year: 2019, Volume and Issue: 8

Published: May 21, 2019

Female Aedes aegypti mosquitoes are deadly vectors of arboviral pathogens and breed in containers freshwater associated with human habitation. Because high salinity is lethal to offspring, correctly evaluating water purity a crucial parenting decision. We found that the DEG/ENaC channel ppk301 sensory neurons expressing control egg-laying initiation choice Ae. aegypti. Using calcium imaging, we ppk301-expressing cells show ppk301-dependent responses but, unexpectedly, also respond salt ppk301-independent fashion. This suggests instructive for at low-salt concentrations, but pathway responsible inhibiting high-salt concentrations. Water key resource insect survival understanding how interact different behaviors an opportunity study evolution chemosensory systems.

Language: Английский

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Variation of preventive practices and its association with malaria infection in eastern Indonesia: Findings from community-based survey

PLoS ONE, Journal Year: 2020, Volume and Issue: 15(5), P. e0232909 - e0232909

Published: May 7, 2020

Geographical variation may likely influence the effectiveness of prevention efforts for malaria across Indonesia, in addition to factors at individual level, household and contextual factors. This study aimed describe preventive practices a levels applied by rural communities five provinces eastern Indonesia its association with incidence among adult (≥15 years) populations.

Language: Английский

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Uncovering the Industrial Potentials of Lemongrass Essential Oil as a Food Preservative: A Review

Antioxidants, Journal Year: 2022, Volume and Issue: 11(4), P. 720 - 720

Published: April 6, 2022

The food industry is growing vastly, with an increasing number of products and the demand consumers to have safe pathogen-free extended shelf life for consumption. It critical from pathogenic bacteria, fungi, unpleasant odors or tastes so that may not cause any health risks consumers. Currently, direction has been shifting synthetically produced preservatives natural lower unnecessary chemical burden on health. Many new technologies are working prevention tools against degradation. Lemongrass one such preservative possesses significant antimicrobial antioxidant activity. essential oil lemongrass contains a series terpenes responsible these activities. These properties make acceptable in fulfill consumer demands. This article provides detailed information about role its preservation. outcomes research offer room technological applications

Language: Английский

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Repellent efficacy of 20 essential oils on Aedes aegypti mosquitoes and Ixodes scapularis ticks in contact-repellency assays

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Jan. 30, 2023

Cases of mosquito- and tick-borne diseases are rising worldwide. Repellent products can protect individual users from being infected by such diseases. In a previous study, we identified five essential oils that display long-distance mosquito repellency using Y-tube olfactometer assay. the current contact repellent efficacy 20 active ingredients Environmental Protection Agency's (EPA) Minimum Risk Pesticides list were tested Aedes aegypti Ixodes scapularis. We utilized an arm-in-cage assay to measure complete protection time bites for these ingredients. To tick repellency, used EPA-recommended procedure crossings. found tested, 10% v/v lotion emulsions with clove oil or cinnamon provided longest both conclude in emulsion, specific EPA provide crossings longer than one hour.

Language: Английский

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Carbon-based single-atom catalysts in advanced oxidation reactions for water remediation: From materials to reaction pathways

Eco-Environment & Health, Journal Year: 2023, Volume and Issue: 2(2), P. 47 - 60

Published: April 26, 2023

Single-atom catalysts (SACs) have been widely recognized as state-of-the-art in environment remediation because of their exceptional performance, 100% metal atomic utilization, almost no secondary pollution, and robust structures. Most recently, the activation persulfate with carbon-based SACs advanced oxidation processes (AOPs) raises tremendous interest degradation emerging contaminants wastewater, owning to its efficient versatile reactive oxidant species (ROS) generation. However, comprehensive critical review unraveling underlying relationship between structures corresponding generated ROS is still rare. Herein, we systematically summarize fundamental understandings intrinsic mechanisms single atom active sites produced during AOPs. The types are firstly elaborated, presenting prior pollutants that need be degraded. Then, preparation characterization methods overviewed. material structure–ROS type persulfate-based AOPs discussed depth expound catalytic mechanisms. Finally, briefly conclude current development propose prospects for rational design synthesis on-demand performances future research.

Language: Английский

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Field evaluation of a volatile pyrethroid spatial repellent and etofenprox treated clothing for outdoor protection against forest malaria vectors in Cambodia

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: July 29, 2024

Abstract Cambodia’s goal to eliminate malaria by 2025 is challenged persistent transmission in forest and fringe areas, where people are exposed Anopheles mosquito bites during the day night. Volatile pyrethroid spatial repellents (VPSRs) insecticide-treated clothing (ITC) could address these gaps. This study evaluated outdoor application of one passive transfluthrin-based VPSR, four etofenprox-ITCs paired with a picaridin topical repellent, combination VPSR ITC against wild landing Cambodia. A 7 × Latin-square was conducted over 49 collection nights temporary open structures Mondulkiri Province. All interventions substantially reduced landing, protective efficacy ranging from 61 95%. Mathematical modeling showed significant reductions vectoral capacity, especially combined alone, albeit decreased effectiveness time. These have potential reduce daytime biting, offering valuable contributions elimination efforts Cambodia Greater Mekong Subregion, contingent upon achieving effective coverage adherence.

Language: Английский

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Repellency of Essential Oils and Plant-Derived Compounds Against Aedes aegypti Mosquitoes

Insects, Journal Year: 2025, Volume and Issue: 16(1), P. 51 - 51

Published: Jan. 7, 2025

Plant-based oils have a long history of use as insect repellents. In an earlier study, we showed that in 10% concentration, geraniol, 2-phenylethl propionate, and the plant-based essential clove cinnamon effectively protected from mosquito bites for over 60 min. To expand on this reanalyzed our GC-MS data to identify short organic constituents these oils. We then used arm-in-cage assay test repellency different concentrations combinations pure compounds. found sigmoidal relationship between complete protection time concentration The times recorded suggest absence additive effects. results study can inform development novel, effective,

Language: Английский

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