Bedtime to the brain: how infants’ sleep behaviours intertwine with non‐rapid eye movement sleep electroencephalography features DOI Creative Commons
Sarah F. Schoch, Valeria Jaramillo, Andjela Markovic

et al.

Journal of Sleep Research, Journal Year: 2023, Volume and Issue: 33(2)

Published: May 22, 2023

Summary Adequate sleep is critical for development and facilitates the maturation of neurophysiological circuitries at basis cognitive behavioural function. Observational research has associated early life problems with worse later cognitive, psychosocial, somatic health outcomes. Yet, extent to which day‐to‐day behaviours (e.g., duration, regularity) in relate non‐rapid eye movement (NREM) neurophysiology—acutely long‐term—remains be studied. We measured 32 healthy 6‐month‐olds assessed actimetry neurophysiology high‐density electroencephalography (EEG) investigate association between NREM habitual behaviours. Our study revealed four findings: first, daytime are related EEG slow‐wave activity (SWA). Second, night‐time awakenings from connected spindle density. Third, timing linked connectivity quantified as delta coherence. And lastly, coherence 6 months predicts duration 12 months. These novel findings widen our understanding that infants’ closely intertwined three particular levels neurophysiology: pressure (determined by SWA), thalamocortical system (spindles), cortical (coherence). The crucial next step extend this concept clinical groups objectively characterise ‘at risk’ foster neurodevelopmental problems.

Language: Английский

Relations between sleep patterns early in life and brain development: A review DOI Creative Commons
Sanna Lokhandwala, Rebecca M. C. Spencer

Developmental Cognitive Neuroscience, Journal Year: 2022, Volume and Issue: 56, P. 101130 - 101130

Published: June 26, 2022

Sleep supports healthy cognitive functioning in adults. Over the past decade, research has emerged advancing our understanding of sleep's role cognition during development. Infancy and early childhood are marked by unique changes sleep physiology patterns as children transition from biphasic to monophasic sleep. Growing evidence suggests that, development, there parallel brain that may modulate structure activity vice versa. In this review, we survey studies development across childhood. By summarizing these findings, provide a importance for Moreover, discuss gaps understanding, which will inform future research.

Language: Английский

Citations

70
Sleep, plasticity, and sensory neurodevelopment DOI Creative Commons
Mark S. Blumberg, James C. Dooley, Alexandre Tiriac

et al.

Neuron, Journal Year: 2022, Volume and Issue: 110(20), P. 3230 - 3242

Published: Sept. 8, 2022

Language: Английский

Citations

43
Protracted development of motor cortex constrains rich interpretations of infant cognition DOI Creative Commons
Mark S. Blumberg,

Karen E. Adolph

Trends in Cognitive Sciences, Journal Year: 2023, Volume and Issue: 27(3), P. 233 - 245

Published: Jan. 20, 2023

Language: Английский

Citations

43
Roles for Sleep in Neural and Behavioral Plasticity: Reviewing Variation in the Consequences of Sleep Loss DOI Creative Commons
Jacqueline T. Weiss, Jeffrey M. Donlea

Frontiers in Behavioral Neuroscience, Journal Year: 2022, Volume and Issue: 15

Published: Jan. 20, 2022

Sleep is a vital physiological state that has been broadly conserved across the evolution of animal species. While precise functions sleep remain poorly understood, large body research examined negative consequences loss on neural and behavioral plasticity. disruption generally results in degraded plasticity cognitive function, impact can vary widely with age, between individuals, contexts. Additionally, several recent studies indicate differentially impacts distinct neuronal populations within memory-encoding circuitry. These findings are not universally shared, identifying conditions influence resilience an organism (or neuron type) to might open future opportunities examine sleep's core brain. Here, we discuss functional roles for adaptive review factors contribute individual variations behavior responses loss.

Language: Английский

Citations

27
Early brain activity: Translations between bedside and laboratory DOI Creative Commons
Heiko J. Luhmann, Patrick O. Kanold, Zoltán Molnár

et al.

Progress in Neurobiology, Journal Year: 2022, Volume and Issue: 213, P. 102268 - 102268

Published: March 29, 2022

Language: Английский

Citations

24
An infant sleep electroencephalographic marker of thalamocortical connectivity predicts behavioral outcome in late infancy DOI Creative Commons
Valeria Jaramillo, Sarah F. Schoch, Andjela Markovic

et al.

NeuroImage, Journal Year: 2023, Volume and Issue: 269, P. 119924 - 119924

Published: Feb. 3, 2023

Infancy represents a critical period during which thalamocortical brain connections develop and mature. Deviations in the maturation of connectivity are linked to neurodevelopmental disorders. There is lack early biomarkers detect localize neuromaturational deviations, can be overcome with mapping through high-density electroencephalography (hdEEG) assessed sleep. Specifically, slow waves spindles non-rapid eye movement (NREM) sleep generated by system, their characteristics, wave slope spindle density, closely related neuroplasticity learning. Spindles often subdivided into (11.0-13.0 Hz) fast (13.5-16.0 frequencies, for not only different functions have been proposed, but also distinctive developmental trajectories reported across first years life. Recent studies further suggest that information processing underlying sleep-dependent learning promoted temporal coupling spindles, yet wave-spindle remains unexplored infancy. Thus, we evaluated three potential biomarkers: 1) slope, 2) 3) spindles. We use hdEEG examine occurrence spatial distribution these EEG features healthy infants second evaluate predictive relationship later behavioral outcomes. report four key findings: First, infants' appear locally: maximal occipital frontal areas, whereas density most pronounced frontocentrally. Second, temporally coupled infancy, strength areas brain. Third, associated concurrent status (6 months). Fourth, central frontocentral regions at age 6 months predicts overall 12 months, motor skills 24 months. Neither nor predict development. identified frequency as determinant accordingly, Our results propose or alternatively frequency, biomarker identifying maturation, potentially used diagnosis disorders infants. These findings support role sensorimotor microcircuitry A crucial next step will whether therapeutic interventions may effective reverse deviations individuals risk.

Language: Английский

Citations

16
Sensorimotor foundations of speech perception in infancy DOI Open Access

Dawoon Choi,

H. Henny Yeung, Janet F. Werker

et al.

Trends in Cognitive Sciences, Journal Year: 2023, Volume and Issue: 27(8), P. 773 - 784

Published: June 10, 2023

Language: Английский

Citations

15
A Thalamocortical Perspective on Sleep Spindle Alterations in Neurodevelopmental Disorders DOI Creative Commons
Carolina Gutierrez Herrera, Leila Tarokh

Current Sleep Medicine Reports, Journal Year: 2024, Volume and Issue: 10(2), P. 103 - 118

Published: March 11, 2024

Abstract Purpose of Review Neurodevelopmental disorders are a group conditions that affect the development and function nervous system, typically arising early in life. These can have various genetic, environmental, and/or neural underpinnings, which impact thalamocortical system. Sleep spindles, brief bursts oscillatory activity occur during NREM sleep, provide unique vivo measure In this manuscript, we review system sleep spindles rodent models humans. We then utilize as foundation to discuss alterations spindle four most pervasive neurodevelopmental disorders—intellectual disability, attention deficit hyperactivity disorder, autism, schizophrenia. Recent Findings work humans has shown across several disorders. Simultaneously, elucidated mechanisms may underlie these deficits activity. This merges recent findings from two separate lines research draw conclusions about pathogenesis Summary speculate associated with exquisitely reflected propose represent promising biomarker for drug discovery, risk stratification, treatment monitoring.

Language: Английский

Citations

6
Open-ended movements structure sensorimotor information in early human development DOI Creative Commons
Hoshinori Kanazawa, Yasunori Yamada, Kazutoshi Tanaka

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2022, Volume and Issue: 120(1)

Published: Dec. 27, 2022

Human behaviors, with whole-body coordination, involve large-scale sensorimotor interaction. Spontaneous bodily movements in the early developmental stage potentially lead toward acquisition of such coordinated behavior. These presumably contribute to structuration interaction, providing specific regularities bidirectional information among muscle activities and proprioception. Whether how spontaneous movements, despite being task-free, structure organize interactions entire body during development remain unknown. Herein, address these issues, we gained insights into process interaction neonates 3-mo-old infants. By combining detailed motion capture musculoskeletal simulation, flows proprioception throughout were obtained. Subsequently, extracted spatial modules temporal state flows. Our approach demonstrated that elicited body-dependent modules, revealing age-related changes them, depending on combination or direction. The also displayed non-random fluctuations analogous those seen cerebral cortex spinal cord. Furthermore, found recurring sequence patterns across multiple participants, characterized by a substantial increase infants compared neonates. Therefore, induce spatiotemporal subsequent changes. results implicated open-ended emerging from certain neural substrate, regulate through embodiment behaviors. findings provide conceptual linkage between neuronal activity terms characteristics.

Language: Английский

Citations

22
The evolution and diversification of sleep DOI
Niels C. Rattenborg, Gianina Ungurean

Trends in Ecology & Evolution, Journal Year: 2022, Volume and Issue: 38(2), P. 156 - 170

Published: Nov. 18, 2022

Language: Английский

Citations

20