A moderated mediation model in assessing links between rumination, emotional reactivity, and suicidal risk in alcohol use disorder DOI Creative Commons
Mateusz Wojtczak, Karol Karasiewicz, Katarzyna Kucharska

et al.

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 28, 2025

Introduction Suicide is a major public health concern, particularly among people with alcohol use disorders (AUD). Rumination, as dysfunctional emotion regulation strategy, and increased emotional reactivity may significantly influence suicide risk in this population. Aim The aim of study was to assess whether different mediate the association between ruminations risk, AUD or control group (HC) status moderates these relationships. Methods A conducted 152 participants, including 86 from 66 HC. Self-report questionnaires measuring ruminations, were used. Structural Equation Modeling, invariance analysis, moderated mediation estimation used analyses. Results analysis full sample revealed significant indirect effect rumination on via reactivity. Multi-group indicated no differences HC groups, neither showing statistically effect. Conclusions findings indicate that serve key mechanism mediating relationship risk. Therapeutic interventions should focus reducing effectively reduce group. Further research needed better understand mechanisms.

Language: Английский

Sensitization of Incentive Salience and the Transition to Addiction DOI
Shelley M. Warlow, Hannah Baumgartner, Charlotte M. Freeland

et al.

Cambridge University Press eBooks, Journal Year: 2020, Volume and Issue: unknown, P. 23 - 37

Published: Aug. 31, 2020

Addiction is characterized by excessive desire for a particular substance or behavioral incentive at the expense of other life rewards. Addictive can develop even in absence any associated increase pleasure, and also withdrawal. Here we review evidence that brain mechanisms underlying 'wanting' operate independently from those mediating "liking." That is, "wanting" "liking" are mediated two anatomically neurochemically distinct normally interact together to influence motivation, but become dissociated transition addiction. Pleasure hedonic impact pleasant stimulus causally amplified system several functionally interactive distributed locations referred as "hedonic hotspots." These hotspots localized subregions within larger structures, relatively sensitive disruption. By contrast, subconscious reward reward-related cues much more robust, system. "Wanting" be generated dopamine enhancements well opioid broadly defined regions throughout mesocorticolimbic circuitry. In susceptible individuals, mesolimbic circuitry hyperreactive sensitized (e.g., through previous drug experience), so "rewards" their related evoke greater release "wanting." Sensitized becomes harder resist, which spur on compulsive pursuit relapse Importantly, this sensitization systems need not accompanied an enhancement (i.e., manipulations do appear effect pleasure). chapter, highlight possible how some drugs behaviors specific focus narrow pursuit, usually involving interactions with areas such amygdala. Further demonstrate addictions food addiction gambling, like addiction,

Language: Английский

Citations

43
Human Neurobiological Approaches to Hedonically Motivated Behaviors DOI
Kyle S. Burger, Grace E. Shearrer, Jennifer R. Sadler

et al.

Cambridge University Press eBooks, Journal Year: 2020, Volume and Issue: unknown, P. 53 - 61

Published: Aug. 31, 2020

Neuroimaging techniques have rapidly expanded our understanding of how the brain responds to addiction in humans. This chapter will discuss methods used assess response, data is analyzed, and it can be better understand addiction. Foundational inferences drawn from these study design. Common designs employed human neuroimaging research are discussed, including cross-sectional designs, longitudinal/cohort experimental designs. A description various their strengths weaknesses included: functional magnetic resonance imaging (fMRI), positron-emission tomography, electroencephalogram, magnetoencephalography, structural MRI, resting state fMRI. Given its popularity research, discussion MRI includes details on paradigm design analysis as well some common oversights processing interpretation results.

Language: Английский

Citations

43
Feedback Models for Gambling Control: The Use and Efficacy of Online Responsible Gambling Tools DOI
Mark D. Griffiths

Cambridge University Press eBooks, Journal Year: 2020, Volume and Issue: unknown, P. 333 - 339

Published: Aug. 31, 2020

Social responsibility in gambling has become a major issue for the gaming industry. This been coupled with rise of behavioural tracking technologies that allow companies to track every decision and action made by gamblers on online sites, slot machines, and/or any type utilizes player cards. chapter number distinct but related aims including: (a) brief overview behavioral accompanied critique both advantages disadvantages such industry researchers; (b) results from series studies completed using data evaluate efficacy responsible tools (particularly relation concerning use social as limit setting, pop-up messaging, personalized feedback gamblers).

Language: Английский

Citations

43
Neuropsychological functioning of patients with major depression or bipolar disorder comorbid to substance use disorders: A systematic review DOI Creative Commons

Nuria Miguel,

Julia E. Marquez-Arrico, Mercé Jódar

et al.

European Neuropsychopharmacology, Journal Year: 2023, Volume and Issue: 75, P. 41 - 58

Published: July 13, 2023

Major depression disorder (MDD) and bipolar (BD) are usual comorbidities in patients with substance use disorders (SUD), a condition known as dual (DD). MDD, BD SUD associated cognitive impairment, potentially leading to greater functional impairment the context of DD.To review existing data on DD comorbid MDD or BD, considering influence depressive symptomatology.Following PRISMA protocol 19 studies were selected from last 17 years, 13 which focused five one included both diagnoses.Studies based BD+SUD showed that most affected domains attention executive functions, but not all them found due comorbidity. While fewer for depression, MDD+SUD works point similar pattern. Furthermore, improvement could be better performance.More standardized research is needed regarding performance patients, especially those MDD. Factors such main substance, abstinence, MDD/BD-related variables should considered. Unstudied factors, like gender circadian rhythms, proposed improve knowledge this area.Current suggest potentiate SUD. However, additional understanding comorbidity apply more individualized therapies treatment these interference their neurocognitive functioning.

Language: Английский

Citations

14
A moderated mediation model in assessing links between rumination, emotional reactivity, and suicidal risk in alcohol use disorder DOI Creative Commons
Mateusz Wojtczak, Karol Karasiewicz, Katarzyna Kucharska

et al.

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 28, 2025

Introduction Suicide is a major public health concern, particularly among people with alcohol use disorders (AUD). Rumination, as dysfunctional emotion regulation strategy, and increased emotional reactivity may significantly influence suicide risk in this population. Aim The aim of study was to assess whether different mediate the association between ruminations risk, AUD or control group (HC) status moderates these relationships. Methods A conducted 152 participants, including 86 from 66 HC. Self-report questionnaires measuring ruminations, were used. Structural Equation Modeling, invariance analysis, moderated mediation estimation used analyses. Results analysis full sample revealed significant indirect effect rumination on via reactivity. Multi-group indicated no differences HC groups, neither showing statistically effect. Conclusions findings indicate that serve key mechanism mediating relationship risk. Therapeutic interventions should focus reducing effectively reduce group. Further research needed better understand mechanisms.

Language: Английский

Citations

0