Azul de Metileno na ração de tilápia-do-Nilo: tratamento inovador para metahemoglobinemia por nitrito DOI Creative Commons

Karoline Moreira Barbuio

Published: March 28, 2024

Hypoxia leads to gill endoplasmic reticulum stress and disruption of mitochondrial homeostasis in grass carp (Ctenopharyngodon idella): Mitigation effect of thiamine DOI
Ke‐Jing Huang, Lin Feng, Pei Wu

et al.

Journal of Hazardous Materials, Journal Year: 2024, Volume and Issue: 469, P. 134005 - 134005

Published: March 12, 2024

Language: Английский

Citations

9
Shrimp Shapes a Nitrite Tolerance Trait via Regulating Autophagy and Apoptosis DOI Open Access
Liping Zhou,

Zhentao Ma,

Qingyun Liu

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(4), P. 1641 - 1641

Published: Feb. 14, 2025

Nitrite is a significant toxic substance that causes acute toxicity in aquatic animals. However, the molecular mechanisms underlying nitrite tolerance remain largely unidentified. Here, we investigated physiological and transcriptomic profiles of nitrite-sensitive nitrite-tolerant families white shrimp Penaeus vannamei under stress. Exposure to lethal concentration for 72 h caused higher mortality, accumulation, more severe damage both hemolymph hepatopancreas than families. This manifested as hepatic tubular deformation, hepatocyte necrosis, decreased hemocyte counts, lowered phagocytic activity hemocytes, elevated production reactive oxygen species (ROS), AKP enzyme activity. Furthermore, analysis revealed an upregulation protein processing endoplasmic reticulum (ER) families, triggering apoptosis- autophagy-related pathways hemocytes upon exposure. Additionally, TUNEL staining transmission electron microscopy (TEM) experiments tolerant may mitigate by modulating autophagy apoptosis. Collectively, our results provide valuable foundation exploring shrimp, which could facilitate targeted breeding germplasm with enhanced aquaculture.

Language: Английский

Citations

1
Protein homeostasis DOI
Noah Esmaeili, Krishna Pada Singha, Vikas Kumar

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 247 - 286

Published: Jan. 1, 2025

Citations

1
Effects of chronic nitrite exposure on hematological parameters, oxidative stress and apoptosis in spotted seabass (Lateolabrax maculatus) reared at high temperature DOI Creative Commons
Chen Shen,

Shi Cao,

Mohamed Mohsen

et al.

Aquaculture Reports, Journal Year: 2024, Volume and Issue: 35, P. 102022 - 102022

Published: March 7, 2024

The effects of nitrite stress on blood biochemistry, antioxidant capacity, and apoptosis spotted seabass (Lateolabrax maculatus) under high-temperature conditions were investigated. Fish subjected to varying levels concentrations for 28 days, specifically 0, 8, 16 mg/L. Blood gill samples collected at the 1st, 3rd, 7th, 14th, 21st 28th exposure index determination, respectively. Results showed that as concentration increased, hemoglobin (Hb) serum chloride ion (Cl-) decreased. In addition, compared control group, methemoglobin (MetHb), hematocrit (HCT), red cells (RBCs), white (WBCs), potassium (K+) significantly increased in nitrite-stressed group. terms antioxidants, catalase (CAT) superoxide dismutase (SOD) activities decreased with increasing concentration. Additionally, malondialdehyde (MDA) content was Regarding genes related apoptosis, expressions hypoxia-inducible factor (Hif-1α) cytochrome C (Cyt-c) up-regulated 1st 3rd day exposure. P53, Bax, Caspase-3, Caspase-8, Caspase-9 groups different time intervals summary, caused disruption balance ions, capacity gills, expression associated ultimately resulting injury seabass.

Language: Английский

Citations

5
Toxic effects of combined exposure to homoyessotoxin and nitrite on the survival, antioxidative responses, and apoptosis of the abalone Haliotis discus hannai DOI Creative Commons
Ye Liang, Yuxin Zhong, Xi Yu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 272, P. 116058 - 116058

Published: Feb. 1, 2024

Homoyessotoxin (homo-YTX) and nitrite (NO

Language: Английский

Citations

4
Silybin prevented avermectin-induced cardiotoxicity in carp by modulating oxidative stress, inflammation, endoplasmic reticulum stress, mitochondrial apoptosis, and autophagy DOI

Jiajie Gan,

Haoming Ma,

Yeyun Ma

et al.

Fish & Shellfish Immunology, Journal Year: 2024, Volume and Issue: 150, P. 109624 - 109624

Published: May 11, 2024

Language: Английский

Citations

4
Nitrite induces hepatic glucose and lipid metabolism disorders in zebrafish through mitochondrial dysfunction and ERs response DOI
Hui Yang,

Kang Ou-Yang,

Ya He

et al.

Aquatic Toxicology, Journal Year: 2024, Volume and Issue: 273, P. 107015 - 107015

Published: June 27, 2024

Language: Английский

Citations

4
Effects of nitrite exposure on the oxidative stress, immune response and intestine microbiota of Procambarus clarkii DOI

Dan‐Dan Bian,

Yan-Xia Shi,

Xi-Rong Zhu

et al.

Aquaculture, Journal Year: 2024, Volume and Issue: 593, P. 741331 - 741331

Published: July 6, 2024

Language: Английский

Citations

4
An insight into nitrite-induced reproductive toxicity and the alleviation of injury by selenomethionine through activation of the Keap1/Nrf2 pathway in Procambarus clarkii DOI

Dan‐Dan Bian,

Xin Liu, Junjie Jiang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 306, P. 141616 - 141616

Published: March 3, 2025

Language: Английский

Citations

0
Mitigation of the toxic effects of nitrite: role and mechanism of isoleucine in mitigating mitochondrial DNA leakage-induced inflammation in grass carp (Ctenopharyngodon idella) under nitrite exposure DOI
Kaixuan Ren, Lin Feng, Pei Wu

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: unknown, P. 138016 - 138016

Published: March 1, 2025

Language: Английский

Citations

0