Environmental Geochemistry and Health, Journal Year: 2024, Volume and Issue: 46(12)
Published: Nov. 19, 2024
Language: Английский
Chemosphere, Journal Year: 2024, Volume and Issue: 351, P. 141227 - 141227
Published: Jan. 21, 2024
Language: Английский
Citations
65
Environment International, Journal Year: 2024, Volume and Issue: 185, P. 108562 - 108562
Published: March 1, 2024
Phthalates (PAEs) and polycyclic aromatic hydrocarbons (PAHs) are frequently detected in females of reproductive age. Many studies have found that environmental PAE PAH levels independent risk factors for gestational hypertension. However, exposure to both components is a more realistic scenario. To better assess the health effects PAEs PAHs pregnant women, we explored associations individual combined with This nested case-control study was component prospective cohort conducted Beijing, China. We included 206 women hypertension 214 controls. used gas chromatography/tandem mass spectrometry (GC-MS/MS) detect 8 13 > 80 % all collected hair samples. Multiple linear regression models were employed test between each A quantile-based g-computation (qgcomp) model weighted quantile sum (WQS) estimate whether increased The analyses revealed diethyl phthalate (DEP), diisobutyl (DIBP) (both PAEs), benzo(k)fluoranthene (BKF), anthracene, (ANT), benzo(a)pyrene (BAP) (all PAHs) positively associated In mixed-effect analyses, qgcomp indicated co-exposure (odds ratio = 2.01; 95 confidence interval: 1.02, 3.94); this finding verified by WQS model. Our findings support earlier evidence increase hypertension, individually combination. suggests reductions endocrine system-disrupting chemicals such as might reduce
Language: Английский
Citations
7
Environmental Research, Journal Year: 2024, Volume and Issue: 255, P. 119205 - 119205
Published: May 21, 2024
Language: Английский
Citations
7
Health Risk Analysis, Journal Year: 2024, Volume and Issue: 1, P. 150 - 157
Published: March 1, 2024
Examining peculiarities of an immune profile and genetic polymorphisms is especially relevant when identifying markers effect sensitivity to exposure benzo(a)pyrene in northern areas. We examined 1253 children who lived industrial centers on conditionally clean territories the north south Eastern Siberia. Levels ambient air children’s blood were determined by using HPLC. TP53 (rs1042522) polymorphism was real-time PCR; p53 levels identified with flow cytofluorometry; IgG benzo(a)pyrene, radioallergosorbent tests. Exposure Northern Siberia airborne at dose 7.11•10-3 µg/(kg•day) causes ben-zo(a)pyrene contamination blood, activates apoptosis (p53) stimulates occurrence specific sensitization (IgG benzo(a)pyrene) (p < 0.05). Similar disorders established Southern under 86.46•10-3 µg/(kg•day). The detected changes profiles living are associated G-allele GG-genotype gene (OR = 1.37–1.83, p 0.05); Siberia, С-allele СС-genotype said 1.55–2.38, Therefore, exposed bears some signs activated These comparable effects produced which same This confirms a hypothesis that technogenic chemical factors can be modulated climatic conditions areas contribution made predisposition. Their combined creates serious risk developing impairments 0.05; RR 1.17; 95 % CI: 1.07–1.27) even low-dose benzo(a)pyrene.
Language: Английский
Citations
4
Foods, Journal Year: 2024, Volume and Issue: 13(13), P. 1977 - 1977
Published: June 22, 2024
Polycyclic aromatic hydrocarbons (PAHs) represent a category of persistent organic pollutants that pose global concern in the realm food safety due to their recognized carcinogenic properties humans. Food can be contaminated with PAHs are present water, air, or soil, during processing and cooking. The wide varied sources contribute contamination food, leading accumulation within these products. As result, monitoring levels is necessary guarantee products as well public health. This review paper attempts give its readers an overview impact on crops, occurrence sources, methodologies employed for sample preparation detection food. In addition, possible directions future research proposed. objective provide references monitoring, prevention, in-depth exploration
Language: Английский
Citations
4
Environmental Research, Journal Year: 2025, Volume and Issue: unknown, P. 120889 - 120889
Published: Jan. 1, 2025
Language: Английский
Citations
0
Ecotoxicology and Environmental Safety, Journal Year: 2025, Volume and Issue: 291, P. 117896 - 117896
Published: Feb. 1, 2025
Exposure to polycyclic aromatic hydrocarbons (PAHs), particularly when bound fine particulate matter (PM2.5), is an emerging concern for adverse prenatal health outcomes. This study investigates the associations between exposure PAHs-bound PM2.5 and markers of inflammation oxidative stress in umbilical cord blood. We conducted a prospective 450 mother-infant pairs, assessing levels during pregnancy using personal air sampling. Inflammatory biomarkers, including TNF-α, IL-6, IL-8, TGF-β, Pro-oxidant Antioxidant Balance (PAB), were measured Multivariable linear regression was used examine individual PAHs these while mixture effects evaluated quantile g-computation Bayesian Kernel Machine Regression (BKMR) assess combined influence 15 PAH congeners. Our findings revealed significant specific increased PAB. Mixture analysis indicated that each one-quartile increase associated with 0.31 pg/mL (95 % CI: 0.05-0.60, p = 0.01), 1.26 0.43-2.08, < 26.02 2.98-49.07, 0.02) respectively. However, IL-6 PAB showed no associations. BKMR further confirmed dose-response relationship elevated inflammatory markers. These highlight potential risks PM2.5, emphasizing need research mitigate developmental effects.
Language: Английский
Citations
0
Atmosphere, Journal Year: 2024, Volume and Issue: 15(2), P. 173 - 173
Published: Jan. 30, 2024
Air pollution includes particle-bound polycyclic aromatic hydrocarbons (PAHs), which eventually reach the placenta, triggering adverse perinatal outcomes through long-term exposure. Lately, air has increased over Metropolitan Area of Medellin-Colombia (MAMC), but its effects on pregnancy are still unknown. In this research, a real-time analysis total airborne PAHs was made using photoelectric sensor for residential places influenced by industrial and traffic sources affecting southern northern MAMC during second peak bimodal tendency PM2.5 emissions in region. Additionally, individual were analyzed GC/MS coupled with pressurized hot water extraction methodology. The data applied an inhalation intake model to assess average concentration three times higher than MAMC, where missed abortion rate been 1.4 according database. Previous research indicates that act as endocrine-disrupting chemicals (EDCs) even heavy congeners could reside umbilical cord blood. Finally, annual series rates exhibited significant correlation levels PM2.5, associated (r2 = 0.69, p < 0.01). While does not imply causality, our results suggest important connection between both variables, opening gap deeper understanding how regions high PAH convergence influence MAMC.
Language: Английский
Citations
2
Reproductive Toxicology, Journal Year: 2024, Volume and Issue: 125, P. 108560 - 108560
Published: Feb. 21, 2024
Language: Английский
Citations
2
Toxicology Reports, Journal Year: 2024, Volume and Issue: 13, P. 101686 - 101686
Published: July 2, 2024
This study explores the concentrations and spatial distribution of polycyclic aromatic hydrocarbons (PAHs) in ambient air Maragheh city, Iran, while evaluating their potential health implications. PAHs levels were examined PAHs-bound to particulate matter samples collected from diverse locations across city. The results showed that all sampling points, there was contamination by PAHs. mean total concentration 11.5 ng.m
Language: Английский
Citations
2