Antioxidant Effects of Medicinal Plants for the Treatment of Epilepsy DOI Creative Commons

Sayed Mohammed Firdous,

Shouvik Mallik,

Bijoy Paria

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: unknown, P. 441 - 489

Published: Nov. 17, 2024

Epilepsy is a chronic neurological disorder characterized by recurrent seizures, affecting millions of individuals worldwide. Despite the availability various antiepileptic drugs (AEDs), substantial number patients continue to experience inadequate seizure control and adverse effects. Consequently, there growing interest in exploring alternative treatment options, including medicinal plants, complement conventional therapies enhance patient outcomes. This book chapter aims provide an overview antioxidant effects plants epilepsy. Oxidative stress, resulting from imbalance between reactive oxygen species (ROS) production body's defense system, has been implicated pathogenesis progression Medicinal rich natural antioxidants offer promising avenue for managing epilepsy modulating oxidative stress. The begins discussing fundamental concepts highlighting intricate interplay these two phenomena. It then delves into diverse classes known their properties potential application management. Various plant extracts phytochemicals, flavonoids, phenolics, terpenoids, alkaloids, are examined ability scavenge free radicals, inhibit lipid peroxidation, endogenous defenses. Furthermore, explores mechanistic insights behind such as activation nuclear factor erythroid 2-related 2 (Nrf2) pathway, modulation mitochondrial function, inhibition pro-inflammatory cytokines. synergy compounds AEDs also discussed, prospect combination therapies. Finally, addresses challenges future directions field Standardization herbal preparations, identification active compounds, rigorous clinical trials crucial establishing safety, efficacy, optimal therapeutic strategies. In summary, this provides comprehensive exploration emphasizes adjunctive therapies, opening new avenues personalized approaches that can improve overall well-being living with

Language: Английский

The role of microbial partners in heavy metal metabolism in plants: a review DOI

Shilin Fu,

Babar Iqbal, Guanlin Li

et al.

Plant Cell Reports, Journal Year: 2024, Volume and Issue: 43(4)

Published: April 1, 2024

Language: Английский

Citations

6
Potential of cotton sticks-derived biochar to alleviate Aluminium toxicity in cotton DOI Creative Commons

Ghulam Murtaza,

Gang Deng, Muhammad Usman

et al.

Industrial Crops and Products, Journal Year: 2025, Volume and Issue: 229, P. 121022 - 121022

Published: April 12, 2025

Language: Английский

Citations

0
Metabolic adjustment via microbial agents and biochar synergy enhances mercury stress tolerance in Vigna radiata L. DOI

Shirwan Malaie,

Latifeh Pourakbar, Sina Siavash Moghaddam

et al.

Acta Physiologiae Plantarum, Journal Year: 2025, Volume and Issue: 47(5)

Published: May 1, 2025

Language: Английский

Citations

0
Phytoremediation of mercury-contaminated Soil by Vigna radiata L. plant in companion with bacterial and fungal biofertilizers DOI

Shirwan Malaie,

Latifeh Pourakbar, Sina Siavash Moghaddam

et al.

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(43), P. 55549 - 55561

Published: Sept. 5, 2024

Language: Английский

Citations

1
Effects of combined application of Se and ammonium fertilizers on the growth and nutritional quality of maize in Hg-polluted soil under two irrigation conditions and its health risk assessment DOI

Yan-zhen Bai,

Xiaoling Lan,

Shaozu Xu

et al.

Chemosphere, Journal Year: 2024, Volume and Issue: 367, P. 143644 - 143644

Published: Nov. 1, 2024

Language: Английский

Citations

1
Heavy metal accumulation, yield and health risk assessment of wheat crop grown in contaminated soil amended with bioash for sustainable agriculture DOI
Umesh Kumar, Prince Kumar Singh, Indrajeet Kumar

et al.

Journal of Food Composition and Analysis, Journal Year: 2024, Volume and Issue: unknown, P. 107140 - 107140

Published: Dec. 1, 2024

Language: Английский

Citations

1
Synergistic interactions of assorted bacterial and fungal agents with biochar ameliorate Vigna radiate L. growth and amino acids adjustment under mercury stress DOI
Sina Siavash Moghaddam,

Shirwan Malaie,

Latifeh Pourakbar

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: July 3, 2024

Abstract Mercury (Hg) as an abiotic stressor poses significant challenges to plant growth. This study investigates the response of Mung bean plants three levels Hg stress (0, 20, and 40 mg/L) using a hydroponic system, inoculated with microbial biostimulators. The two-factorial experiment focused on growth, total soluble sugars (TSS), free amino acids. Results indicated decrease in biomass increasing severity. Under moderate (20 mg/L Hg), arbuscular mycorrhizae (AM) were effective preserving biomass, while under severe (40 combination biochar, AM, bacterial biostimulants (BAB) was most effective. highest recorded by combined treatment bacteria AM (BaAM) although it dropped sharply conditions. Except for BaAM, TSS content increased all treatments, particularly notably enhanced BAB stress. generally amount Pro, Phe, Tyr, Trp, Asn, Gly, Val exposed stress, Asp decreased across treatments. Higher tolerance linked greater accumulation specific acids like Asn. interaction inoculation suggests that adapt mercury toxicity altering their sugar acid profiles, which serve multifunctional molecules precursors resistance metabolites.

Language: Английский

Citations

0
Antioxidant Effects of Medicinal Plants for the Treatment of Epilepsy DOI Creative Commons

Sayed Mohammed Firdous,

Shouvik Mallik,

Bijoy Paria

et al.

Antioxidants, Journal Year: 2024, Volume and Issue: unknown, P. 441 - 489

Published: Nov. 17, 2024

Epilepsy is a chronic neurological disorder characterized by recurrent seizures, affecting millions of individuals worldwide. Despite the availability various antiepileptic drugs (AEDs), substantial number patients continue to experience inadequate seizure control and adverse effects. Consequently, there growing interest in exploring alternative treatment options, including medicinal plants, complement conventional therapies enhance patient outcomes. This book chapter aims provide an overview antioxidant effects plants epilepsy. Oxidative stress, resulting from imbalance between reactive oxygen species (ROS) production body's defense system, has been implicated pathogenesis progression Medicinal rich natural antioxidants offer promising avenue for managing epilepsy modulating oxidative stress. The begins discussing fundamental concepts highlighting intricate interplay these two phenomena. It then delves into diverse classes known their properties potential application management. Various plant extracts phytochemicals, flavonoids, phenolics, terpenoids, alkaloids, are examined ability scavenge free radicals, inhibit lipid peroxidation, endogenous defenses. Furthermore, explores mechanistic insights behind such as activation nuclear factor erythroid 2-related 2 (Nrf2) pathway, modulation mitochondrial function, inhibition pro-inflammatory cytokines. synergy compounds AEDs also discussed, prospect combination therapies. Finally, addresses challenges future directions field Standardization herbal preparations, identification active compounds, rigorous clinical trials crucial establishing safety, efficacy, optimal therapeutic strategies. In summary, this provides comprehensive exploration emphasizes adjunctive therapies, opening new avenues personalized approaches that can improve overall well-being living with

Language: Английский

Citations

0