Polystyrene Nanomicroplastics Aggravate Ammonia-Induced Neurotoxic Effects in Zebrafish Embryos DOI Creative Commons

Dan Xing,

Wenting Zheng,

Zhou Hui-ming

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(12), P. 853 - 853

Published: Nov. 26, 2024

The highly hazardous chemical ammonia has been proven to be absorbed by nanoparticles, thereby exerting toxic effects on aquatic organisms. As a ubiquitous pollutant in environments, polystyrene nanomicroplastics (PSNPs) have shown strong adsorption capacity due their large surface area. Therefore, the potential joint of and PSNPs need clarified. In this study, zebrafish embryos were exposed water solution with concentrations (0, 0.1, 1, 10 mg/L) or without PSNP (100 μg/L) treatment up 120 hpf. results showed that combined exposure increased accumulation obviously reduced locomotor speed larvae compared alone. Further studies indicated can aggravate ammonia-induced neurotoxicity altering cholinergic system, dopaminergic neurons, retinal structure larvae. addition, our revealed caused significant alterations expression genes related neurodevelopment development, exacerbated adverse effect. conclusion, early stage associated health risk animals should not underestimated. main contribution article lies revealing synergistic zebrafish. Moreover; it emphasizes risks

Language: Английский

Tri-iso-butyl phosphate (TiBP) exposure induces neurotoxicity by triggering oxidative stress accompanied by neurotransmitter system disruptions and apoptosis in zebrafish larvae DOI

Congying Luo,

Qiong Zhang, Dinghui Wang

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 363, P. 125137 - 125137

Published: Oct. 17, 2024

Language: Английский

Citations

1
Effect of functional groups of polystyrene nanoplastics on the neurodevelopmental toxicity of acrylamide in the early life stage of zebrafish DOI

Haohan Yang,

Linghui Kong,

Zhuoyu Chen

et al.

Aquatic Toxicology, Journal Year: 2024, Volume and Issue: 278, P. 107177 - 107177

Published: Nov. 25, 2024

Language: Английский

Citations

1
Polystyrene Nanomicroplastics Aggravate Ammonia-Induced Neurotoxic Effects in Zebrafish Embryos DOI Creative Commons

Dan Xing,

Wenting Zheng,

Zhou Hui-ming

et al.

Toxics, Journal Year: 2024, Volume and Issue: 12(12), P. 853 - 853

Published: Nov. 26, 2024

The highly hazardous chemical ammonia has been proven to be absorbed by nanoparticles, thereby exerting toxic effects on aquatic organisms. As a ubiquitous pollutant in environments, polystyrene nanomicroplastics (PSNPs) have shown strong adsorption capacity due their large surface area. Therefore, the potential joint of and PSNPs need clarified. In this study, zebrafish embryos were exposed water solution with concentrations (0, 0.1, 1, 10 mg/L) or without PSNP (100 μg/L) treatment up 120 hpf. results showed that combined exposure increased accumulation obviously reduced locomotor speed larvae compared alone. Further studies indicated can aggravate ammonia-induced neurotoxicity altering cholinergic system, dopaminergic neurons, retinal structure larvae. addition, our revealed caused significant alterations expression genes related neurodevelopment development, exacerbated adverse effect. conclusion, early stage associated health risk animals should not underestimated. main contribution article lies revealing synergistic zebrafish. Moreover; it emphasizes risks

Language: Английский

Citations

0