Molecules,
Journal Year:
2018,
Volume and Issue:
23(9), P. 2199 - 2199
Published: Aug. 30, 2018
A
series
of
caffeic
acid
derivatives
were
synthesized
via
a
modified
Wittig
reaction
which
is
very
important
tool
in
organic
chemistry
for
the
construction
unsaturated
carbon–carbon
bonds.
All
reactions
performed
water
medium
at
90
°C.
The
aqueous
worked
best
when
one
unprotected
hydroxyl
group
was
present
phenyl
ring.
olefinations
conditions
also
conducted
with
good
yields
presence
two
groups.
When
number
groups
increased
to
three,
worse,
and
12,
13,
18
obtained
74%,
37%,
70%
yields,
respectively.
Nevertheless,
using
as
essential
an
elegant
one-pot
synthesis
greener
method,
can
be
safe
alternative
implementation
chemistry.
compounds
tested
their
antioxidant
activity,
showed
highest
activities.
Moreover,
all
displayed
no
cytotoxicity,
therefore
used
pharmaceutical
or
cosmetic
industry.
Plants,
Journal Year:
2019,
Volume and Issue:
8(4), P. 96 - 96
Published: April 11, 2019
Eight
selected
wild
vegetables
from
Nepal
(Alternanthera
sessilis,
Basella
alba,
Cassia
tora,
Digera
muricata,
Ipomoea
aquatica,
Leucas
cephalotes,
Portulaca
oleracea
and
Solanum
nigrum)
were
investigated
for
their
antioxidative
potential
using
2,2-dyphenyl-1-picrylhydrazyl
(DPPH)
scavenging,
hydrogen
peroxide
(H2O2),
ferric
reducing
antioxidant
power
(FRAP),
thiocyanate
(FTC)
methods.
Among
the
plant
extracts
C.
tora
displayed
highest
DPPH
radical
scavenging
activity
with
an
IC50
value
9.898
μg/mL,
whereas
A.
sessilis
had
maximum
H2O2
16.25
μg/mL—very
close
to
that
of
ascorbic
acid
(16.26
μg/mL).
showed
absorbance
in
FRAP
assay
lowest
lipid
peroxidation
FTC
assay.
A
methanol
extract
resulted
greatest
phenolic
content
(292.65
±
0.42
mg
gallic
equivalent
(GAE)/g)
measured
by
Folin–Ciocalteu
reagent
method,
while
smallest
was
recorded
B.
alba
(72.66
0.46
GAE/g).
The
flavonoid
observed
P.
(39.38
0.57
quercetin
equivalents
(QE)/g)
as
aluminium
chloride
colorimetric
least
I.
aquatica
(6.61
QE/g).
There
a
strong
correlation
between
total
(DPPH,
R2
=
0.75;
H2O2,
0.71)
0.84;
0.66).
This
study
demonstrates
these
edible
leafy
plants
could
be
source
natural
antioxidants.
Frontiers in Nutrition,
Journal Year:
2020,
Volume and Issue:
7
Published: May 7, 2020
Phenolic
compounds
are
broadly
represented
in
plant
kingdom,
and
their
occurrence
easily
accessible
low-cost
sources
like
wastes
from
agri-food
processing
have
led
the
last
decade
to
an
increase
of
interest
recovery
further
exploitation.
Indeed,
most
these
endowed
with
beneficial
properties
human
health
(e.g.
prevention
cancer
cardiovascular
diseases),
that
may
be
largely
ascribed
potent
antioxidant
scavenging
activity
against
reactive
oxygen
species
generated
settings
oxidative
stress
responsible
for
onset
several
inflammatory
degenerative
diseases.
Apart
use
as
food
supplements
or
additives
functional
foods,
natural
phenolic
become
increasingly
attractive
also
a
technological
point
view,
due
possible
exploitation
materials
science.
Several
extraction
methodologies
been
reported
mostly
based
on
organic
solvents
such
methanol,
ethanol,
acetone.
However,
there
is
increasing
need
green
sustainable
approaches
leading
phenolic-rich
extracts
low
environmental
impact.
This
review
addresses
promising
innovative
waste
appeared
recent
literature.
In
particular,
procedures
technologies
(supercritical
fluid,
microwaves,
ultrasounds)
well
deep
eutectic
(DES)
surveyed
Animals,
Journal Year:
2022,
Volume and Issue:
12(3), P. 245 - 245
Published: Jan. 20, 2022
The
aim
of
the
study
was
to
present
a
review
literature
data
on
antioxidant
potential
raw
milk
and
dairy
products
(milk,
fermented
products,
cheese)
possibility
modify
its
level
at
production
processing
stage.
Based
available
reports,
it
can
be
concluded
that
consumption
are
rich
source
bioactive
components
improves
status
organism
reduces
risk
development
many
civilization
diseases.
Milk
undoubtedly
sources
compounds.
Various
methods,
in
particular,
ABTS,
FRAP,
DPPH
assays,
used
for
measurement
overall
activity
products.
Research
indicates
differences
total
capacity
between
animal
species,
which
result
from
chemical
compositions
their
milk.
content
modified
through
nutrition
(e.g.,
supplementation
diets
with
various
natural
additives
(herbal
mixtures,
waste
fruit
vegetable
processing)).
is
associated
quality
material
as
well
bacterial
cultures
plant
used.
Antioxidant
peptides
released
during
fermentation
increase
use
probiotic
strains
contributes
enhancement.
Investigations
have
shown
enhanced
by
addition
materials
or
extracts
process.
Natural
should
therefore
widely
functional
Nutrients,
Journal Year:
2022,
Volume and Issue:
14(17), P. 3519 - 3519
Published: Aug. 26, 2022
Phenolic
compounds
are
natural
phytochemicals
that
have
recently
reported
numerous
health
benefits.
Resveratrol,
curcumin,
and
quercetin
received
the
most
attention
among
these
molecules
due
to
their
documented
antioxidant
effects.
The
review
aims
investigate
effects
of
on
bone
metabolism
role
in
several
diseases
such
as
osteopenia
osteoporosis,
tumours,
periodontitis.
PubMed/Medline,
Web
Science,
Google
Scholar,
Scopus,
Cochrane
Library,
Embase
electronic
databases
were
searched
for
papers
line
with
study
topic.
According
an
English
language
restriction,
screening
period
was
from
January
2012
3
July
2022,
following
Boolean
keywords:
(“resveratrol”
AND
“bone”);
(“curcumin”
(“quercetin”
“bone”).
A
total
36
identified
relevant
purpose
our
investigation.
studies
positive
investigated
phenolic
potential
application
adjuvant
treatments
Furthermore,
use
titanium
surfaces
orthopaedic
prostheses
could
represent
a
possible
improve
osteogenic
processes
osseointegration.
findings,
resveratrol,
wide
variety
beneficial
supplement
therapies.
seem
positively
mediate
osteoclast-related
pathologies.
Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
33(49)
Published: July 26, 2023
Abstract
Chronic
refractory
wounds
have
become
a
severe
threat
to
public
health
and
are
characterized
by
repeated
bacterial
infections,
persistent
hypoxia,
abnormal
immune
regulation,
obstruction
of
angiogenesis.
However,
current
treatment
strategies
usually
perform
only
one
or
two
therapeutic
functions
cannot
satisfy
the
dynamic
complex
demands
chronic
wound
healing.
Herein,
versatile
Schiff
base
borate
ester
cross‐linked
glycopeptide
hydrogel
is
prepared
from
phenylboronic
acid‐grafted
ε‐polylysine
(EPBA),
epigallocatechin‐3‐gallate
(EGCG),
oxidized
alginate.
Customized
polydopamine‐coated
honeycomb
MnO
2
nanoparticles
loaded
with
herb‐derived
salvianolic
acid
B
(PHMS)
embedded
into
before
gelation.
Under
distinct
acidic
oxidative
microenvironment
wounds,
gradually
dissociates,
released
EPBA
effectively
eliminates
bacteria,
while
EGCG
PHMS
eradicates
reactive
oxygen
nitrogen
species,
promotes
M2
polarization
macrophages,
continuously
generates
oxygen.
Then
further
disintegrates,
angiogenesis
through
PI3K/Akt
pathway.
The
accelerates
Staphylococcus
aureus
‐infected
diabetic
cutaneous
repair
in
vivo
promising
candidate
dressing
for
Sustainability,
Journal Year:
2023,
Volume and Issue:
15(11), P. 9075 - 9075
Published: June 4, 2023
Grapes,
particularly
the
species
Vitis
vinifera
L.,
are
one
of
most
widely
grown
crops
in
world.
Winemaking
processes
generate
a
high
amount
residues,
which
currently
pose
an
environmental
and
economic
sustainability
problem
for
companies
sector.
For
this
reason,
solutions
being
explored
development
new
products
with
high-added
value
derived
from
valorization
these
residues.
One
wastes
produced
by
winemaking
is
grape
pomace,
chemical
composition
promising
because
it
rich
compounds
antioxidant
activity,
such
as
polyphenols
(anthocyanins,
flavonols,
flavan-3-ols,
procyanidins),
phenolic
acids,
resveratrol,
fiber.
Commonly
pomace
used
to
produce
distillates
extract
tartaric
acid
coloring
substances
enocyanin.
Recently,
alternative
uses
have
been
adopted,
production
extracts
properties,
fermentation
substrates,
composting
biomass
energy
production,
fiber
extraction
high-value-added
enriched
bioactive
molecules
pomace.
Here,
we
discuss
how
involved
various
human
biological
functions
their
applications
agri-food
Veterinary Sciences,
Journal Year:
2023,
Volume and Issue:
10(1), P. 55 - 55
Published: Jan. 14, 2023
Chronic
stress
is
recognized
as
a
secret
killer
in
poultry.
It
associated
with
systemic
inflammation
due
to
cytokine
release,
dysbiosis,
and
the
so-called
leaky
gut
syndrome,
which
mainly
results
from
oxidative
reactions
that
damage
barrier
function
of
cells
lining
wall.
Poultry,
especially
genetically
selected
broiler
breeds,
frequently
suffer
these
chronic
symptoms
when
exposed
multiple
stressors
their
growing
environments.
Since
inflammatory
damages
are
multi-stage
long-term
processes,
overshooting
immune
down-stream
effects
also
negatively
affect
animal's
microbiota,
finally
impair
its
performance
commercial
value.
Means
counteract
poultry
other
animals
are,
therefore,
highly
welcome.
Many
phytogenic
substances,
including
flavonoids
phenolic
compounds,
known
exert
anti-inflammatory
antioxidant
effects.
In
this
review,
firstly,
main
poultry,
such
heat
stress,
mycotoxins,
dysbiosis
diets
contain
oxidized
lipids
trigger
inflammation,
discussed,
along
key
transcription
factors
involved
related
signal
transduction
pathways.
Secondly,
most
promising
substances
current
applications
ameliorate
highlighted.
