Frontiers in Drug Safety and Regulation, Journal Year: 2023, Volume and Issue: 3
Published: March 31, 2023
SPECIALTY GRAND CHALLENGE article Front. Drug Saf. Regul., 31 March 2023Sec. Maternal-Fetal Medicine Volume 3 - 2023 | https://doi.org/10.3389/fdsfr.2023.1187070
Language: Английский
Vaccines, Journal Year: 2022, Volume and Issue: 10(5), P. 766 - 766
Published: May 12, 2022
Mass vaccination against COVID-19 is essential to control the pandemic. vaccines are now recommended during pregnancy prevent adverse outcomes. With this review, we aimed evaluate evidence in literature regarding uptake of vaccinations among pregnant women. A comprehensive search was performed PubMed, Medline, Scopus, ProQuest, Web Science, CINAHL, and medRxiv from inception 23 March 2022. We a meta-analysis estimate overall proportion women vaccinated COVID-19. found 11 studies including 703,004 The 27.5% (95% CI: 18.8–37.0%). Predictors were older age, ethnicity, race, trust vaccines, fear pregnancy. Mistrust government, diagnosis pregnancy, fears about safety side effects reasons for declining vaccination. global prevalence low. large gap exists on factors influencing decision be Targeted information campaigns increase vaccine literacy
Language: Английский
Citations
79
International Journal of Gynecology & Obstetrics, Journal Year: 2022, Volume and Issue: 159(3), P. 651 - 661
Published: July 10, 2022
Language: Английский
Citations
36
Vaccines, Journal Year: 2022, Volume and Issue: 10(12), P. 2055 - 2055
Published: Nov. 30, 2022
Mass vaccination against COVID-19 is necessary to control the pandemic. vaccines are now recommended during pregnancy prevent disease. A systematic review of literature in electronic databases PubMed and EMBASE was performed we aimed investigate attitude documents towards prognostic factors hesitation. meta-analysis also conducted estimate overall percentage pregnant women who were willing be vaccinated or had been COVID-19. total 18 studies included meta-analysis. The acceptance rate among ranged from 17.6% 84.5%. pooled proportion 0.53 (95% CI: 0.44-0.61). Predictors older age, White race, occupational status, higher level education, comorbidities, third trimester pregnancy, influenza vaccination, knowledge about COVID-19, confidence that for safe effective. prevalence low. Targeted information campaigns needed increase vaccine education this population.
Language: Английский
Citations
23
PLoS ONE, Journal Year: 2023, Volume and Issue: 18(3), P. e0282525 - e0282525
Published: March 2, 2023
Background Vaccination during pregnancy has been repeatedly demonstrated to be safe and effective in protecting against infection associated harms for the mother, developing baby, subsequent infant. However, maternal vaccination uptake remains low compared general population. Objectives An umbrella review explore barriers facilitators Influenza, Pertussis COVID-19 within 2 years after childbirth, inform interventions encourage (PROSPERO registration number: CRD42022327624). Methods Ten databases were searched systematic reviews published between 2009 April 2022 exploring predictors of or effectiveness improve Pertussis, COVD-19. Both pregnant women mothers infants under two included. Barriers organised using WHO model determinants vaccine hesitancy through narrative synthesis, Joanna Briggs Institute checklist assessed quality, degree overlap primary studies was calculated. Results 19 Considerable found especially intervention reviews, quality included their varied. Sociodemographic factors specifically researched context COVID-19, exerting a small but consistent effect on vaccination. Concerns around safety particularly baby main barrier. While key recommendation from healthcare professional, previous vaccination, knowledge communication with support social groups. Intervention indicated multi-component involving human interaction most effective. Conclusion The have identified constitute foundation policy development at international level. Ethnicity, socioeconomic status, concerns about side effects, lack professionals’ recommendations, are relevant hesitancy. Adapting educational specific populations, person-to-person interaction, involvement, interpersonal important strategies uptake.
Language: Английский
Citations
16
medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2022, Volume and Issue: unknown
Published: April 1, 2022
Abstract Background Mass vaccination against the COVID-19 is essential to control pandemic. vaccines are recommended now during pregnancy prevent adverse outcomes. Objective To evaluate evidence from literature regarding uptake of among pregnant women. Methods We conducted a systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. searched PubMed, Medline, Scopus, ProQuest, Web Science, CINAHL, pre-print service (medRxiv) inception March 23, 2022. included quantitative studies reporting women, that examine predictors reasons decline vaccination. performed meta-analysis estimate overall proportion vaccinated women COVID-19. Results found 11 including 703,004 The was 27.5% (95% CI: 18.8-37.0%). pooled were in Israel higher than USA other countries. Predictors older age, ethnicity, race, trust vaccines, fear pregnancy. On hand, mistrust government, diagnosis with pregnancy, worry about safety side effects Conclusions global prevalence low. There large gap on factors influencing decision be Targeted information campaigns improve build vaccine literacy Given ongoing high case rates known increased risks our findings could help policy makers acceptance rate especially vulnerable subgroups.
Language: Английский
Citations
21
Frontiers in Pediatrics, Journal Year: 2024, Volume and Issue: 12
Published: April 19, 2024
Introduction Despite recommendations for COVID-19 vaccination in pregnant people, the effect of on neonatal outcomes remains unknown. We sought to determine association between status pregnancy and presence neonatally diagnosed congenital anomalies. Methods A comprehensive vaccine registry was combined with a delivery database create cohort including all patients aged 16–55 years event December 10, 2020 31, 2021 at hospital within Mayo Clinic Health System. Pregnancy were analyzed relation timing, composite measure anomalies life. Comparisons cohorts conducted using chi-square test categorical Kruskal–Wallis continuous variables. multivariable logistic regression modeled assess Results 5,096 mother-infant pairs analyzed. total 1,158 vaccinated, 314 vaccinated first trimester. status, during trimester pregnancy, not associated an increased risk When further examining by organ system, we did demonstrate significant difference eye, ear, face, neck groups (Table 3, Not = 2.3%, Vaccinated 3.3%, p -value 0.04) however this 1st (Not Trimester 2.5%, 0.77). No differences found or any other systems. There no birthweight gestational age, APGAR scores, incidence NICU admission, living neonate status. Conclusion add additional information regarding safety timing as it pertains anomalies, demonstrated. Our findings agree prior literature that is adverse small age neonates. Further research needed elucidate neck,
Language: Английский
Citations
4
American Journal of Obstetrics & Gynecology MFM, Journal Year: 2022, Volume and Issue: 4(5), P. 100654 - 100654
Published: May 2, 2022
Language: Английский
Citations
16
Expert Review of Vaccines, Journal Year: 2022, Volume and Issue: 21(10), P. 1487 - 1493
Published: July 20, 2022
Background During the rollout of COVID-19 vaccination, many states relaxed mask wearing guidance for those vaccinated. The aim this study was to examine association between vaccination status and behaviors.
Language: Английский
Citations
10
Journal of Clinical Medicine, Journal Year: 2022, Volume and Issue: 11(16), P. 4720 - 4720
Published: Aug. 12, 2022
(1) Background: The adverse-effect profile and short-term obstetric neonatal outcomes among pregnant women who were vaccinated with the BNT162b2 vaccine at any stage of pregnancy do not indicate safety concerns. is effective in generating a humoral immune response women. (2) Objective: To determine vaccine-induced immunity adverse events associated third (booster) dose compared to first second (3) Study design: A prospective cohort study tertiary referral center comparing by (Pfizer/BioNTech) dose, between January November 2021. digital questionnaire regarding was filled both groups 2−4 weeks after vaccination. Blood samples collected tested for SARS-COV-2 IgG antibodies 28−32 days administration or dose. (4) Results: Seventy-eight received doses eighty-four vaccine. In terms following vaccination, local rash/pain/swelling (93.6% vs. 72.6%, p < 0.001) significantly less common vaccination Other events, including early complications, did differ two groups. SARS-CoV-2 serum levels higher (1333.75 2177.93, respectively, 0.001). (5) Conclusion: This confirms immunogenicity, lack complications second- third-dose stronger
Language: Английский
Citations
10
Vaccines, Journal Year: 2022, Volume and Issue: 10(8), P. 1369 - 1369
Published: Aug. 22, 2022
Italy has been one of the hardest hit countries in European Union since beginning SARS-CoV-2 pandemic, and Regione Lombardia (RL) reported largest number cases country. This population-based retrospective study analyzed RL records 122,942 pregnant women to describe vaccination uptake population, compare vaccine vs. childbearing age evaluate impact status on admissions intensive care units during 2021. Vaccination according citizenship educational level comparison between non-pregnant was performed by Z test. A logistic regression groups. Out women, 79.9% were vaccinated at end The rate significantly lower versus but increased after issuing official recommendations. Vaccine administration higher among with Italian a high education all trimesters. In conclusion, role recommendations explicit communication about importance safety pregnancy is critical obtain trust acceptance women.
Language: Английский
Citations
10