Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: April 29, 2024
Overuse
of
antibiotics
is
accelerating
the
antimicrobial
resistance
among
pathogenic
microbes
which
a
growing
public
health
challenge
at
global
level.
Higher
causes
severe
infections,
high
complications,
longer
stays
hospitals
and
even
increased
mortality
rates.
Antimicrobial
(AMR)
has
significant
impact
on
national
economies
their
systems,
as
it
affects
productivity
patients
or
caregivers
due
to
prolonged
hospital
with
economic
costs.
The
main
factor
AMR
includes
improper
excessive
use
antimicrobials;
lack
access
clean
water,
sanitation,
hygiene
for
humans
animals;
poor
infection
prevention
control
measures
in
hospitals;
medicines
vaccines;
awareness
knowledge;
irregularities
legislation.
represents
problem,
epidemiological
surveillance
systems
have
been
established,
aiming
promote
collaborations
directed
well-being
human
animal
balance
ecosystem.
MDR
bacteria
such
E.
coli
,
Staphylococcus
aureus
Pseudomonas
aeruginosa
Enterococcus
spp.,
Acinetobacter
Klebsiella
pneumonia
can
cause
death.
These
microorganisms
variety
antibiotic
mechanisms,
development
drug-deactivating
targets,
alterations
decrease
intracellular
concentration,
render
themselves
resistant
numerous
antibiotics.
In
context,
United
Nations
issued
Sustainable
Development
Goals
(SDGs)
2015
serve
worldwide
blueprint
better,
more
equal,
sustainable
existence
our
planet.
SDGs
place
context
socioeconomic
issues;
also,
continued
growth
may
hinder
achievement
SDGs.
this
review,
we
discuss
role
environmental
pollution
rise
AMR,
different
mechanisms
underlying
resistance,
threats
posed
by
microbes,
novel
antibiotics,
strategies
One
Health
combat
sustainability
goals.
Frontiers in Microbiology,
Journal Year:
2021,
Volume and Issue:
12
Published: March 29, 2021
Antibiotic
resistance
genes
(ARGs)
are
a
relatively
new
type
of
pollutant.
The
rise
in
antibiotic
observed
recently
is
closely
correlated
with
the
uncontrolled
and
widespread
use
antibiotics
agriculture
treatment
humans
animals.
Resistant
bacteria
have
been
identified
soil,
animal
feces,
housing
(e.g.,
pens,
barns,
or
pastures),
areas
around
farms,
manure
storage
facilities,
guts
farm
selection
pressure
caused
by
irrational
production
sectors
not
only
promotes
survival
existing
antibiotic-resistant
but
also
development
resistant
forms.
One
most
critical
hot-spots
related
to
dissemination
ARGs
livestock
poultry
production.
Manure
widely
used
as
fertilizer
thanks
its
rich
nutrient
organic
matter
content.
However,
research
indicates
that
application
may
pose
severe
threat
human
health
facilitating
arable
soil
edible
crops.
This
review
examines
pathogens,
potentially
pathogenic
microorganisms
which
be
found
manure,
evaluates
their
effect
on
through
exposure
plant
resistomes.
It
takes
broader
view
than
previous
studies
this
topic,
discussing
recent
data
animals
these
practices
composition
manure;
it
how
fertilization
alter
crop
microbiomes,
proposes
drivers
such
changes
consequences
for
health.
Environment International,
Journal Year:
2019,
Volume and Issue:
131, P. 105026 - 105026
Published: July 24, 2019
Antibiotic
resistance
genes
(ARGs)
have
been
considered
as
emerging
contaminants
of
concern
nowadays.
There
are
no
special
technologies
designed
to
directly
remove
ARGs
in
wastewater
treatment
plants
(WWTPs).
In
order
reduce
the
risk
ARGs,
it
is
vital
understand
efficiency
advanced
removing
antibiotic
WWTPs.
This
review
highlights
application
and
tertiary
on
elimination
s,
based
an
understanding
their
occurrence
fate
These
include
chemical-based
processes
such
chlorination,
ozonation,
ultraviolet,
oxidation
technology,
well
physical
separation
processes,
biological
constructed
wetland
membrane
bioreactor,
soil
aquifer
treatment.
The
merits,
limitations
ameliorative
measures
these
discussed,
with
view
optimizing
future
strategies
identifying
new
research
directions.
Frontiers in Microbiology,
Journal Year:
2021,
Volume and Issue:
12
Published: Oct. 11, 2021
This
paper
reviews
current
knowledge
on
sources,
spread
and
removal
mechanisms
of
antibiotic
resistance
genes
(ARGs)
in
microbial
communities
wastewaters,
treatment
plants
downstream
recipients.
Antibiotic
is
the
most
important
tool
to
cure
bacterial
infections
humans
animals.
The
over-
misuse
antibiotics
have
played
a
major
role
development,
spread,
prevalence
(AR)
microbiomes
animals,
ecosystems
worldwide.
AR
can
be
transferred
amongst
bacteria
Chemical Engineering Journal,
Journal Year:
2019,
Volume and Issue:
367, P. 304 - 313
Published: Feb. 2, 2019
Secondary
urban
wastewater
samples
were
spiked
with
azithromycin
(AZT),
trimethoprim
(TMP),
ofloxacin
(OFL)
and
sulfamethoxazole
(SMX)
at
100
µg
L−1
to
investigate
the
efficiency
of
a
TiO2-photocatalytic
treatment
using
UVA-LEDs.
Different
operating
parameters
studied,
such
as
irradiation
conditions,
catalyst
load
use
methanol
carrier
solvent
radical
scavenger.
The
most
efficient
conditions
treat
(4
LEDs
symmetrically
distributed
1.00
g
catalyst)
also
assessed
on
removal
antibiotics
real
concentrations,
well
inactivation
regrowth
bacteria
after
3-day
storage
(total
resistant
heterotrophs,
Escherichia
coli
enterococci).
Clindamycin
(CLI)
was
targeted
when
SMX
not
detected.
One-hour
enough
reduce
analysed
values
below
detection
limits
decrease
bacterial
by
2
log-units.
Bacterial
observed
for
total
photocatalytic
treated
wastewater,
close
pre-treatment.
However,
antibiotic
resistance
percentage
stored
always
similar
or
lower
than
that
secondary
wastewater.
Thus,
potential
this
process
part
tertiary
is
demonstrated,
but
must
be
adjusted
minimize
microbial
regrowth.
