Chemical profiling of paper recycling grades using GC-MS and LC-MS: An exploration of contaminants and their possible sources

Waste Management, Journal Year: 2024, Volume and Issue: 189, P. 148 - 158

Published: Aug. 27, 2024

Paper packaging made with recycled paperboard is used to pack various consumer goods that can include amongst others, electronics, toys, food, cosmetics, and stationery. Chemical profiling of the paper recycling grades in manufacture was undertaken investigate possible sources contaminants their propagation chain. Pre-consumer, retail post-consumer paper-based materials were collected at papermills, corrugators, grocery stores, household waste, solid waste disposal sites facilities. In GC-MS analysis, phthalates, long-chain aliphatic compounds, fatty acids most commonly detected compounds whilst phthalates bisphenols featured prevalently LC-MS analysis. The factors identified as likely contributors detection different chemical included presence wood derivatives, use certain additives during manufacturing, exposure from consumers, other environment. Waste mingling, recovery, sorting reprocessing into also shown influence profile materials. Sparse partial least squares-discriminate analysis indicated newspaper office had unique constituents, cartons have higher variability. By looking key stages recycling, this study showed persistence transformation must be evaluated when considering recyclability Further, it highlighted separation approaches may required reduce contaminant opportunities

Language: Английский

Evaluation of THP-1 and Jurkat Cell Lines Coculture for the In Vitro Assessment of the Effects of Immunosuppressive Substances

Toxics, Journal Year: 2024, Volume and Issue: 12(8), P. 607 - 607

Published: Aug. 19, 2024

The strong appeal to reduce animal testing calls for the development and validation of in vitro, chemico silico models that would replace need vivo ex materials. A category requires such new approach methods is assessment immunosuppression can be induced by chemicals including environmental pollutants. To assess immunosuppressive action on monocytes lymphocytes, we mimicked whole-blood cytokine-release assay preparing an vitro coculture THP-1 Jurkat cell lines. We optimised its activation investigated effects known drugs with different mechanisms release proinflammatory cytokines. Decreased secretion IL-8 was achieved several therefore selected as appropriate marker immunosuppression. set environmentally occurring bisphenols, BPA, BPAP, BPP, BPZ, BPE, TCBPA BPS-MAE, were then applied model BPP BPZ found act potent immunosuppressants at micromolar concentrations.

Language: Английский

Prenatal exposure to environmental bisphenols over time and their association with childhood asthma, allergic rhinitis and atopic dermatitis in the ECHO consortium

Environmental Pollution, Journal Year: 2024, Volume and Issue: unknown, P. 125415 - 125415

Published: Nov. 1, 2024

Language: Английский