Poultry Science,
Journal Year:
2024,
Volume and Issue:
104(1), P. 104490 - 104490
Published: Nov. 12, 2024
Polyvinyl
chloride
microplastics
(PVC-MPs)
and
Cadmium
(Cd)
are
widely
occurring
water
pollutants
that
interact
with
each
other
to
exert
toxic
effects.
As
a
waterfowl,
Muscovy
duck
is
more
susceptible
PVC-MPs
Cd
than
land
poultry.
In
this
study,
was
used
as
research
model,
10
mg/L
50
mg/kg
were
alone
in
combine
explore
the
effect
on
kidney
of
duck.
We
found
treatment
or
changed
weight,
increased
creatinine
urea
nitrogen
content,
disrupted
oxidative
balance
macro/trace
element
metabolism,
while
combination
PVC-MPs+Cd
reduced
accumulation
kidney.
addition,
caused
mitochondrial
damage,
increase
decrease
mitochondria-associated
proteins
(Fis1,
Drp1,
PGC-1α,
Nrf1),
Nrf2
signaling
pathway
plays
key
role
detoxification
alleviation
stress,
we
recovered
related
(Nrf2,
Keap-1,
HO-1,
NQO1,
AC-SOD
Life,
Journal Year:
2025,
Volume and Issue:
15(3), P. 392 - 392
Published: March 3, 2025
Micro-
and
nano-plastics
(MNPs)
are
small
plastic
particles
that
result
from
the
breakdown
of
larger
plastics.
They
widely
dispersed
in
environment
pose
a
threat
to
wildlife
humans.
MNPs
present
almost
all
everyday
items,
including
food,
drinks,
household
products.
Air
inhalation
can
also
lead
exposure
MNPs.
Research
animals
indicates
once
absorbed,
they
spread
various
organs,
liver,
spleen,
heart,
lungs,
thymus,
reproductive
kidneys,
even
brain
by
crossing
blood–brain
barrier.
Furthermore,
MPs
transport
persistent
organic
pollutants
or
heavy
metals
invertebrates
higher
levels
food
chain.
When
ingested,
additives
monomers
comprise
disrupt
essential
biological
processes
human
body,
thereby
leading
disturbances
endocrine
immune
systems.
During
2019
coronavirus
(COVID-19)
pandemic,
there
was
significant
increase
global
use
polypropylene-based
face
masks,
insufficient
waste
management
exacerbating
pollution.
This
review
examines
existing
research
on
impact
MNP
lung
kidney
health
based
vitro
vivo
studies.
Over
past
decades,
wide
range
studies
suggest
both
tissues
under
healthy
diseased
conditions.
Therefore,
this
emphasizes
need
for
additional
employing
multi-approach
analyses
associated
biomarkers
mechanisms
gain
comprehensive
precise
understanding
health.
The
ubiquitous
presence
of
micro/nanoplastics
(MP/NP)
in
the
atmosphere
has
raised
significant
concerns
about
their
potential
health
risks
through
inhalation,
yet
effects
natural
respiratory
exposure
remain
underexplored.
This
study
addresses
this
critical
knowledge
void
by
utilizing
a
whole-body
inhalation
system
to
investigate
distribution,
accumulation,
and
pulmonary
toxicity
polystyrene
MP/NP
(1.5
×
105
particles/m3)
male
ICR
mice
(n
=
16/group).
Fluorescently
labeled
revealed
highest
particle
accumulation
lungs,
followed
bloodstream
spleen,
with
minimal
detection
brain.
Unsurprisingly,
80
nm
nanoplastics
displayed
greater
intertissue
transport
efficiency
than
1
μm
microplastics.
Chronic
both
microplastics
disrupted
oxidative
balance
exacerbated
stress
within
extracellular
environment
lungs.
impaired
antioxidant
defenses
intra-
metabolism
led
inflammation,
apoptosis,
fibrosis.
Intriguingly,
induced
more
severe
smaller
counterparts,
promoting
epithelial-mesenchymal
transition
These
findings
underscore
need
for
nuanced
understanding
size-dependent
toxicities
inhalable
plastic
particles
highlight
posed
airborne
MP/NP.
Atmosphere,
Journal Year:
2025,
Volume and Issue:
16(4), P. 476 - 476
Published: April 19, 2025
Pyrolysis
coupled
with
gas
chromatography–mass
spectrometry
(Py-GC/MS)
is
a
novel
technology
capable
of
detecting
micro-
and
nanoplastics
without
size
limit.
However,
the
application
Py-GC/MS
to
airborne
microplastic
analysis
remains
inconsistent.
This
study
explores
optimal
procedures
using
domestic
HenxiTM
PY-1S
pyrolyzer-based
Py-GC/MS.
The
initial
weight
loss
PVC
occurs
at
approximately
260
°C,
indicating
that
maximum
thermal
desorption
temperature
prior
pyrolysis
should
not
exceed
250
°C.
To
avoid
interference
from
semi-volatile
organics
present
in
sample
injected
air,
it
essential
purge
pure
helium
elevated
temperatures
before
pyrolysis.
Microplastic
standards
can
be
prepared
by
ultrasonicating
water–microplastic
dispersion
system.
Significant
interactions
between
mixtures
were
observed
during
co-pyrolysis,
cannot
ignored
optimization
quantitative
references.
procedure
features
good
linearity
(R2
>
0.98),
low
detection
limit
(0.06~0.0002
μg),
acceptable
precisions
(RSD
<
10%
8
days).
Microplastics
determined
pyrolyzer
GC/MS
system
are
comparable
those
well-established
PY-3030D-based
Py-GC/MS,
reliable
powerful
tool
for
analysis.
Chemosphere,
Journal Year:
2024,
Volume and Issue:
368, P. 143702 - 143702
Published: Nov. 1, 2024
Inhalation
is
one
of
the
main
exposure
routes
to
nanoplastics.
Knowledge
toxicological
impact
nanoplastics
on
airway-
and
lung
epithelium
limited
almost
exclusively
based
submerged
in
vitro
models
using
spherical
polystyrene
(PS)
particles.
Particle and Fibre Toxicology,
Journal Year:
2024,
Volume and Issue:
21(1)
Published: Dec. 4, 2024
Airborne
micro-
and
nanoplastics
(AMNPs)
are
ubiquitously
present
in
human
living
environments
pose
significant
threats
to
respiratory
health.
Currently,
much
research
has
been
conducted
on
the
relationship
between
(MNPs)
cardiovascular
gastrointestinal
diseases,
yet
there
is
a
clear
lack
of
understanding
regarding
link
AMNPs
diseases.
Therefore,
it
imperative
explore
two.
Recent
extensive
studies
by
numerous
scholars
characteristics
their
with
diseases
have
robustly
demonstrated
that
from
various
sources
significantly
influence
onset
progression
conditions.
Thus,
investigating
intrinsic
mechanisms
involved
finding
necessary
preventive
therapeutic
measures
crucial.
In
this
review,
we
primarily
describe
fundamental
AMNPs,
impact
system,
toxic
facilitate
disease
development.
It
hoped
article
will
provide
new
insights
for
further
contribute
advancement
