bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 12, 2024
Abstract
Pesticides
often
harm
beneficial
insect
pollinators,
impairing
their
ability
to
navigate
the
environment,
learn,
fight
off
disease,
and
reproduce.
Understanding
mechanisms
behind
these
disorders
is
essential
for
improving
pesticide
risk
assessments.
To
test
whether
exposure
induces
similar
or
distinct
transcriptional
responses
across
tissues,
we
administered
field-realistic
dose
of
common
neonicotinoid
clothianidin
Bombus
terrestris
bumble
bees.
We
then
measured
gene
expression
in
brains,
hind
femurs,
Malpighian
tubules.
Our
analyses
revealed
that
82%
differences
were
tissue-specific.
Although
genes
associated
with
energy
metabolism
consistently
down-regulated
all
primarily
affected
core
tissue
functions,
namely
linked
ion
transport
brain,
muscle
function
femur,
detoxification
Furthermore,
while
brain
holds
highest
abundance
target
receptors,
other
tissues
showed
more
substantial
magnitude.
These
findings
reveal
causes
complex,
tissue-specific
effects
rather
than
a
uniform
body-wide
response.
study
provides
mechanistic
basis
severe
on
bees
shows
how
transcriptomics
can
help
pinpoint
most
areas
processes
body.
Accordingly
focusing
toxicological
assays
could
significantly
improve
precision
safety
evaluations.
Annual Review of Entomology,
Journal Year:
2023,
Volume and Issue:
69(1), P. 551 - 576
Published: Oct. 12, 2023
Bees
are
essential
pollinators
of
many
crops
and
wild
plants,
pesticide
exposure
is
one
the
key
environmental
stressors
affecting
their
health
in
anthropogenically
modified
landscapes.
Until
recently,
almost
all
information
on
routes
impacts
came
from
honey
bees,
at
least
partially
because
they
were
only
model
species
required
for
risk
assessments
(ERAs)
insect
pollinators.
Recently,
there
has
been
a
surge
research
activity
focusing
effects
non-
Apis
including
other
social
bees
(bumble
stingless
bees)
solitary
bees.
These
taxa
vary
substantially
another
several
important
ecological
traits,
spatial
temporal
patterns,
foraging
nesting
requirements,
degree
sociality.
In
this
article,
we
review
current
evidence
base
about
pathways
consequences
We
find
that
insights
into
bee
resulting
across
biological
organizations,
landscapes,
mixtures,
multiple
still
infancy.
The
good
news
promising
approaches
could
be
used
to
advance
our
understanding,
with
priority
given
informing
pathways,
extrapolating
effects,
determining
how
well
(limited
very
few
mostly
neonicotinoid
insecticides
under
unrealistic
conditions)
can
generalized
diversity
lifestyles
global
community.
conclude
future
expand
knowledge
would
also
beneficial
ERAs
wider
policy
decisions
concerning
pollinator
conservation
regulation.
International Journal for Parasitology Parasites and Wildlife,
Journal Year:
2022,
Volume and Issue:
18, P. 232 - 243
Published: June 13, 2022
There
is
clear
evidence
for
wild
insect
declines
globally.
Habitat
loss,
climate
change,
pests,
pathogens
and
environmental
pollution
have
all
been
shown
to
cause
detrimental
effects
on
insects.
However,
interactive
between
these
stressors
may
be
the
key
understanding
reported
declines.
Here,
we
review
literature
pesticide
pathogen
interactions
bees,
identify
knowledge
gaps,
suggest
avenues
future
research
fostering
mitigation
of
observed
The
limited
studies
available
that
pesticides
most
likely
override
pathogens.
Bees
feeding
flowers
building
sheltered
nests,
are
less
adapted
toxins
compared
other
insects,
which
potential
susceptibility
enhanced
by
reduced
number
genes
encoding
detoxifying
enzymes
with
species.
date
10
using
a
fully-crossed
design
conducted
in
laboratory
social
bees
Crithidia
spp.
or
Nosema
spp.,
identifying
an
urgent
need
test
solitary
Similarly,
since
do
not
necessarily
reflect
field
conditions,
semi-field
essential
if
understand
their
real-world.
In
conclusion,
there
empirical
(semi-)field
range
pesticides,
pathogens,
species
better
pathways
mechanisms
underlying
interactions,
particular
relevance
fitness
population
dynamics.
Such
data
indispensable
drive
forward
robust
modelling
different
settings
foster
predictive
science.
This
will
enable
put
into
context
more
broadly,
evaluating
relative
importance
driving
Ultimately,
this
development
effective
measures
protect
ecosystem
services
they
supply.
Ecotoxicology and Environmental Safety,
Journal Year:
2021,
Volume and Issue:
225, P. 112785 - 112785
Published: Sept. 17, 2021
Neonicotinoids
are
among
the
most
widely
used
insecticides
worldwide,
and
as
such,
have
garnered
increasing
attention
from
scientific
community
in
regards
to
their
potentially
negative
environmental
impacts.
Recently,
degradability
of
neonicotinoid
soil
has
gained
more
attentions.
However,
what
role
microbes
play
this
degradation
remains
vastly
underexplored.
In
study,
we
compared
capacity
sampled
different
geographic
regions
fields
degrade
insecticide
imidacloprid.
Additionally,
composition
microbiota
having
low,
middle,
high
activity
was
analyzed
via
throughput
sequencing.
Correlations
between
activities
were
reconfirmed.
The
results
showed
that
(ranged
zero
96.25%)
varied
significantly
samples
locations.
Correlation
analysis
Paracoccus
Achromobacter
bacteria
positively
correlated
with
activity.
Imidacloprid
experiments
using
these
sp.
alone
exhibited
reaching
sustaining
100%
by
day
20
while
did
not.
combining
resulted
increased
which
reached
at
15
relative
achieved
alone.
This
study
demonstrated
imidacloprid,
identified
two
promising
bacterial
candidates
could
be
future
reduce
imidacloprid
accumulation
soils.
Journal of Applied Ecology,
Journal Year:
2022,
Volume and Issue:
59(6), P. 1596 - 1607
Published: April 24, 2022
Abstract
Recent
reports
on
bee
health
suggest
that
sublethal
doses
of
pesticides
have
negative
effects
wild
reproduction
and
ultimately
their
population
growth.
Females
the
solitary
horned
mason
Osmia
cornuta
,
evaluate
thoracic
vibrations
odours
males
to
assess
male
quality.
When
certain
criteria
are
met,
female
accepts
copulates.
However,
these
signals
were
found
be
modified
by
in
other
hymenopterans.
Here,
we
tested
whether
a
commonly
used
fungicide
(Fenbuconazole)
impact
quality
mating
success
O.
.
Males
exposed
fenbuconazole
exhibited
reduced
an
altered
cuticular
hydrocarbon
profile
compared
control
bees.
Moreover,
less
successful
than
males.
Synthesis
applications
Our
results
indicate
low
toxicity
can
negatively
affect
reproductive
altering
behavioural
chemical
cues.
This
could
explain
decreasing
pollinator
populations
pesticide‐polluted
environment.
study
highlights
need
for
more
comprehensive
approach,
including
behaviour
cues,
when
testing
new
cautionary
approach
already
crops.
