One-Step Microwave Synthesis of Excitation Dependent Photostability and High Fluorescence Quantum Yield Cr-Cpds for Advanced Multifaceted Applications DOI

Yushu Han,

Xin Kong, Lunzhao Yi

et al.

Published: Jan. 1, 2023

Carbon polymer dots (CPDs) show incredible potential due to their outstanding optical characteristics, simple synthesis using low-cost precursors, and diverse applications. This study aimed develop chromium-doped CPDs (Cr-CPDs) an efficient one-step microwave method for fluorescence sensing optoelectronic devices. The one-pot used citric acid, urea, C6H9O6Cr, N, N-dimethylformamide. resulting Cr-CPDs demonstrated excitation dependent photostability with a high quantum yield of 15.56%, making them promising fluorescence-based Our experiments showed the Cr-CPDs' could be effectively quenched in presence Fe3+ ions, allowing detection down 0.52 μM concentration. By combining PVA, flexible composite films were created visual ion sensing. Static quenching IFE dynamics work synergistically underpin selective sensitive fluorescent function Fe3+.These further served as colorful inks multifunctional information encoding. Most significantly, incorporating into PVA assembling on LEDs led blue green light-emitting opens new possibilities cost-effective luminescent materials next-gen electronics.

Language: Английский

Amino acid metabolism disorder and oxidative stress took part in EGCG alleviating Mn-caused ferroptosis via miR-9-5p/got1 axis DOI
Qin Zhou,

Zhiyu Hao,

Ming-Yue Qiu

et al.

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 489, P. 137656 - 137656

Published: Feb. 21, 2025

Language: Английский

Citations

3
Ferroptosis implication in environmental-induced neurotoxicity DOI
Yiping Zhang,

Jun Xie

The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 934, P. 172618 - 172618

Published: April 24, 2024

Language: Английский

Citations

11
Synthesis of Naringenin and Senecioic Acid Ester Derivatives and Biological Evaluation of the Astrocyte Antioxidant Mechanism and Reactivity After Inflammatory Stimulus DOI Open Access
Janaína Ribeiro Pereira Soares,

Cleonice Creusa dos Santos,

Lucas Matheus Gonçalves de Oliveira

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(5), P. 2215 - 2215

Published: Feb. 28, 2025

The imbalance between the overproduction of reactive species and antioxidant mechanisms can result in astrogliosis oxidative stress associated with neurodegeneration. Based on described activity naturally occurring flavonoids, this study evaluated flavonoid naringenin senecioic acid ester derivatives cortical astrocytes. Naringenin (S)-naringenin were purified from Citrus paradisi, them 7,4-O-disenecioic naringenin, (S)-7,4-O-disenecioic 7-O-senecioic synthesized tested for by free-radical scavenging reaction DPPH. flavonoids' toxicity glutathione (GS) depletion determined rat astrocyte cultures; effects astrocytes' reactivity was expression glial fibrillary acidic protein (GFAP) measuring nitric oxide (NO) production astrocytes treated lipopolysaccharide (LPS, 1 µg/mL/24 h). compounds (1-10 μM) presented effects, (S)-7,4'-O-disenecioic most effective. (1-100 not toxic to astrocytes, also promoting an effect increasing GSH. Moreover, 7-O-senecioc mitigated induced LPS, reducing GFAP NO production. These findings indicate that present a pharmacological potential as anti-inflammatory brain diseases via modulation response.

Language: Английский

Citations

1
A novel genetically encoded fluorescent probe for rapid Hg2 + analysis in environmental samples and elucidation of cellular uptake pathways DOI

Tianyu Song,

Xinyue Shen, Jing Tang

et al.

Sensors and Actuators B Chemical, Journal Year: 2025, Volume and Issue: 439, P. 137842 - 137842

Published: April 23, 2025

Language: Английский

Citations

0
Excitation-Dependent Photostability and High Fluorescence Quantum Yield of Cr-Doped Carbon Polymer Dots for Sensors, Anticounterfeiting Inks, and Light-Emitting Devices DOI

Yushu Han,

Xin Kong,

Rui Bao

et al.

ACS Applied Nano Materials, Journal Year: 2024, Volume and Issue: 7(2), P. 1674 - 1683

Published: Jan. 10, 2024

Carbon polymer dots (CPDs) show incredible potential due to their outstanding optical characteristics, simple synthesis using low-cost precursors, and diverse applications. This study aimed develop chromium-doped CPDs (Cr-CPDs) an efficient one-step microwave method for fluorescence sensing optoelectronic devices. The one-pot used citric acid, urea, C6H9O6Cr, N,N-dimethylformamide. resulting Cr-CPDs demonstrated excitation-dependent photostability with a high quantum yield of 15.56%, making them promising fluorescence-based Our experiments showed that the Cr-CPDs' could be effectively quenched in presence Fe3+ ions, allowing detection down 0.52 μM concentration. By combination PVA, flexible composite films were created visual ion sensing. Static quenching IFE dynamics work synergistically underpin selective sensitive fluorescent function Fe3+. These further served as colorful inks multifunctional information encoding. Most significantly, incorporating into PVA assembling on light-emitting devices (LEDs) led blue- green LEDs. opens new possibilities cost-effective luminescent materials next-gen electronics.

Language: Английский

Citations

3
miR-15b-5p promotes HgCl2-induced chicken embryo kidney cells ferroptosis by targeting β-TrCP-mediated ATF4 ubiquitin degradation DOI

Hongyu Fu,

Yue Li,

Han Cui

et al.

Toxicology, Journal Year: 2024, Volume and Issue: 503, P. 153742 - 153742

Published: Feb. 6, 2024

Language: Английский

Citations

3
Ferroptosis involvement in the neurotoxicity of flunitrazepam in zebrafish DOI

Yingjun Qin,

Wenting Lin, Yuan Ren

et al.

Aquatic Toxicology, Journal Year: 2024, Volume and Issue: unknown, P. 107128 - 107128

Published: Oct. 1, 2024

Language: Английский

Citations

0
Therapeutic potential of 4-phenylbutyric acid against methylmercury-induced neuronal cell death in mice DOI Creative Commons
Ryohei Miki, Ryosuke Nomura,

Yuta Iijima

et al.

Archives of Toxicology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 27, 2024

Abstract Methylmercury (MeHg) is an environmental neurotoxin that induces damage to the central nervous system and causative agent in Minamata disease. The mechanisms underlying MeHg neurotoxicity remain largely unknown, there a need for effective therapeutic agents, such as those target MeHg-induced endoplasmic reticulum (ER) stress unfolded protein response (UPR), which activated defense mechanism. We investigated whether intraperitoneal administration of chemical chaperone, 4-phenylbutyric acid (4-PBA), at 120 mg/kg/day can alleviate brains mice administered 50 ppm drinking water 5 weeks. 4-PBA significantly reduced ER stress, neuronal apoptosis, neurological symptoms. Furthermore, was even when 2 weeks after initiation exposure 30 water. Our results strongly indicate UPR are key processes involved toxicity, novel candidate neurotoxicity.

Language: Английский

Citations

0
One-Step Microwave Synthesis of Excitation Dependent Photostability and High Fluorescence Quantum Yield Cr-Cpds for Advanced Multifaceted Applications DOI

Yushu Han,

Xin Kong, Lunzhao Yi

et al.

Published: Jan. 1, 2023

Carbon polymer dots (CPDs) show incredible potential due to their outstanding optical characteristics, simple synthesis using low-cost precursors, and diverse applications. This study aimed develop chromium-doped CPDs (Cr-CPDs) an efficient one-step microwave method for fluorescence sensing optoelectronic devices. The one-pot used citric acid, urea, C6H9O6Cr, N, N-dimethylformamide. resulting Cr-CPDs demonstrated excitation dependent photostability with a high quantum yield of 15.56%, making them promising fluorescence-based Our experiments showed the Cr-CPDs' could be effectively quenched in presence Fe3+ ions, allowing detection down 0.52 μM concentration. By combining PVA, flexible composite films were created visual ion sensing. Static quenching IFE dynamics work synergistically underpin selective sensitive fluorescent function Fe3+.These further served as colorful inks multifunctional information encoding. Most significantly, incorporating into PVA assembling on LEDs led blue green light-emitting opens new possibilities cost-effective luminescent materials next-gen electronics.

Language: Английский

Citations

0