Environmental Research, Journal Year: 2020, Volume and Issue: 185, P. 109284 - 109284
Published: Feb. 21, 2020
Language: Английский
The Science of The Total Environment, Journal Year: 2020, Volume and Issue: 763, P. 143028 - 143028
Published: Oct. 21, 2020
Language: Английский
Citations
42
Toxins, Journal Year: 2023, Volume and Issue: 15(7), P. 448 - 448
Published: July 6, 2023
The rapid rise of microcystins (MCs) poses a serious threat to global freshwater ecosystems and has become an important issue public health. MCs have considerable stability are the most widely distributed hepatotoxins. It cannot only accumulate in aquatic organisms transfer higher nutrients levels, but also be degraded or transferred during resource utilization cyanobacteria. No matter which enrichment method, it will lead risk human exposure. This review summarizes research status MCs, introduces distribution different components ecosystems. was summarized, potential risks environment safety were summarized. polluted all areas In order protect life from health threats caused by this paper proposes some future directions promote control reduce exposure MCs.
Language: Английский
Citations
15
Environmental Science & Technology, Journal Year: 2024, Volume and Issue: 58(3), P. 1473 - 1483
Published: Jan. 11, 2024
Though toxins produced during harmful blooms of cyanobacteria present diverse risks to public health and the environment, surface water quality surveillance cyanobacterial is inconsistent, spatiotemporally limited, routinely relies on ELISA kits estimate total microcystins (MCs) in waters. Here, we employed liquid chromatography tandem mass spectrometry examine common cyanotoxins, including five microcystins, three anatoxins, nodularin, cylindrospermopsin, saxitoxin 20 subtropical reservoirs spatially distributed across a pronounced annual rainfall gradient. Probabilistic environmental hazard analyses identified whether values for cyanotoxins were exceeded if these exceedances varied spatiotemporally. MC-LR was most congener detected, but it not consistently observed with other toxins, MC-YR, which detected at highest concentrations spring many observations above California human recreation guideline (800 ng/L). Cylindrospermopsin also quantitated 40% eutrophic reservoirs; detections did exceed US Environmental Protection Agency swimming/advisory level (15,000 Our have implications routine monitoring practices, traditionally use MC levels often limit collection samples summer months near reservoir impoundments, further indicate that spatiotemporal efforts are necessary understand when occur throughout year.
Language: Английский
Citations
5
Environmental Research, Journal Year: 2024, Volume and Issue: 248, P. 118251 - 118251
Published: Jan. 24, 2024
Language: Английский
Citations
5
Journal of Cleaner Production, Journal Year: 2024, Volume and Issue: 441, P. 141011 - 141011
Published: Jan. 29, 2024
Language: Английский
Citations
5
Toxins, Journal Year: 2021, Volume and Issue: 13(10), P. 711 - 711
Published: Oct. 8, 2021
Cyanotoxin occurrence is gaining importance due to anthropogenic activities, climate change and eutrophication. Among them, Microcystins (MCs) Cylindrospermopsin (CYN) are the most frequently studied their ubiquity toxicity. Although MCs primary classified as hepatotoxins CYN a cytotoxin, they have been shown induce deleterious effects in wide range of organs. However, on immune system yet scarcely investigated. Thus, know impact cyanotoxins system, its organisms’ homeostasis, considered interest. A review scientific literature dealing with immunotoxicity has performed, both vitro vivo studies considered. Results confirmed scarcity reports topic, particularly for CYN. Decreased cell viability, apoptosis or altered functions cells, changed levels mRNA expression cytokines among common reported. Underlying mechanisms, however, still not fully elucidated. Further research needed order full picture cyanotoxin immunotoxicity.
Language: Английский
Citations
30
Toxins, Journal Year: 2023, Volume and Issue: 15(2), P. 127 - 127
Published: Feb. 4, 2023
In recent years, the consumption of blue-green algae (BGA) dietary supplements is increasing because their health benefits. However, cyanobacteria can produce cyanotoxins, which present serious risks. this work we propose hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry (HILIC-MS/MS) to determine cyanotoxins in BGA supplements. Target toxins, including microcystin-leucine-arginine (MC-LR) and microcystin-arginine-arginine (MC-RR), nodularin, anatoxin-a three non-protein amino acids, β-N-methylamino-L-alanine (BMAA), 2,4-diaminobutyric acid (DAB) N-(2-aminoethyl)glycine (AEG), were separated using a SeQuant ZIC-HILIC column. Cyanotoxin extraction was based on solid–liquid (SLE) followed by tandem-solid phase (SPE) procedure Strata-X mixed-mode cation-exchange (MCX) cartridges. The method validated for obtaining quantification limits from 60 300 µg·kg−1. Nine different commercial analyzed, DAB, AEG, MCs found some samples, highlighting relevance monitoring these substances as precaution measures safe products.
Language: Английский
Citations
12
Veterinary World, Journal Year: 2025, Volume and Issue: unknown, P. 189 - 201
Published: Jan. 1, 2025
Cyanobacterial blooms, driven by anthropogenic and climatic changes, pose significant ecological health threats. This study investigates the long-term effects of microcystins (MCs), potent cyanotoxins, on cattle at Lake des Oiseaux, a Ramsar-listed wetland in Algeria. Aligning with "One Health" framework, research evaluates biochemical, histological, oxidative stress impacts MCs livestock as environmental sentinels. A herd 40 (20 exposed 20 non-exposed) was studied during summer bloom period 2019. Blood liver samples were analyzed to assess biochemical markers (ALT, AST, ALP, GGT, etc.), histopathological parameters (GPx, CAT, SOD, LPO GSH). Exposed exhibited elevations enzymes markers, indicating hepatic inflammation redox imbalance. Histological analysis revealed macrovacuolar steatosis, fibrosis, bile duct dilatation. Antioxidant enzyme activities CAT SOD) reduced, notable depletion GSH levels increased lipid peroxidation. These findings reflect cumulative cytotoxic MC exposure. Non-exposed showed no such changes. Long-term exposure disrupts function induces cattle, implicating risks for both animal human health. The bioaccumulation cyanotoxins emphasizes urgent need preventive measures, including water monitoring, restricted access contaminated sites, farmer education. strategies are vital mitigate under approach, ensuring sustainable public
Language: Английский
Citations
0
Reviews in Environmental Science and Bio/Technology, Journal Year: 2025, Volume and Issue: unknown
Published: March 2, 2025
Language: Английский
Citations
0
Toxins, Journal Year: 2025, Volume and Issue: 17(3), P. 126 - 126
Published: March 7, 2025
Cyanobacterial harmful algal blooms (cyanoHABs) are a natural phenomenon produced mainly by the interaction between and anthropogenic events. CyanoHABs characterized production of cyanotoxins that can have effects on different species within food web even affect human health. Among most prevalent toxin groups worldwide microcystins (MCs), anatoxins (ATXs), cylindrospermopsins (CYNs) nodularins (NODs), which as toxins with hepatotoxic, neurotoxic, cytotoxic effects. This review summarizes analyzes research influence cyanoHABs, main toxin-producing cyanobacteria in freshwater marine bodies, highlighting their global occurrence, toxicology, bioaccumulation dynamics vectors web, cases acute chronic intoxications humans. is useful for understanding cyanoHABs’ ecosystem impact health, how implementation surveillance management framework could generate vital information stakeholders to establish health guidelines risks hazards cyanoHABs
Language: Английский
Citations
0