Wastewater surveillance to infer COVID-19 transmission: A systematic review

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 804, P. 150060 - 150060

Published: Sept. 8, 2021

Successful detection of SARS-COV-2 in wastewater suggests the potential utility wastewater-based epidemiology (WBE) for COVID-19 community surveillance. This systematic review aims to assess performance surveillance as early warning system transmission. A search was conducted PubMed, Medline, Embase and WBE Consortium Registry according PRISMA guidelines relevant articles published until 31st July 2021. Relevant data were extracted summarized. Quality each paper assessed using an assessment tool adapted from Bilotta et al.'s environmental science. Of 763 studies identified, 92 distributed across 34 countries shortlisted qualitative synthesis. total 26,197 samples collected between January 2020 May 2021 various locations serving population ranging 321 11,400,000 inhabitants. Overall sample positivity moderate at 29.2% all examined settings with spike (S) gene having maximum rate positive detections nucleocapsid (N) being most targeted. Wastewater signals preceded confirmed cases by up 63 days, 13 reporting before first detected community. At least 50 reported association viral load cases. While cannot replace large-scale diagnostic testing, it can complement clinical providing signs transmission more active public health responses. However, standardized validated methods are required along risk analysis modelling understand dynamics outbreaks.

Language: Английский

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SARS-CoV-2 Wastewater Surveillance for Public Health Action

Emerging infectious diseases, Journal Year: 2021, Volume and Issue: 27(9), P. 1 - 8

Published: Aug. 19, 2021

Abstract Wastewater surveillance for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has garnered extensive public attention during the disease pandemic as a proposed complement to existing systems. Over past year, methods detection and quantification of SARS-CoV-2 viral RNA in untreated sewage have advanced, concentrations wastewater been shown correlate with trends reported cases. Despite promise surveillance, these measurements translate into useful health tools, bridging communication knowledge gaps between researchers responders is needed. We describe key uses, barriers, applicability supporting decisions actions, including establishing ethics consideration monitoring. Although assess community infections not new idea, might be initiating event make this emerging tool sustainable nationwide system, provided that barriers are addressed.

Language: Английский

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SARS-CoV-2 and other pathogens in municipal wastewater, landfill leachate, and solid waste: A review about virus surveillance, infectivity, and inactivation

Environmental Research, Journal Year: 2021, Volume and Issue: 203, P. 111839 - 111839

Published: Aug. 4, 2021

Language: Английский

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Correlation between SARS-CoV-2 RNA concentration in wastewater and COVID-19 cases in community: A systematic review and meta-analysis

Journal of Hazardous Materials, Journal Year: 2022, Volume and Issue: 441, P. 129848 - 129848

Published: Aug. 28, 2022

Language: Английский

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Artificial neural network-based estimation of COVID-19 case numbers and effective reproduction rate using wastewater-based epidemiology

Water Research, Journal Year: 2022, Volume and Issue: 218, P. 118451 - 118451

Published: April 13, 2022

Language: Английский

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Recent progress on wastewater-based epidemiology for COVID-19 surveillance: A systematic review of analytical procedures and epidemiological modeling

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 878, P. 162953 - 162953

Published: March 21, 2023

Language: Английский

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Wastewater surveillance of SARS-CoV-2 and influenza in preK-12 schools shows school, community, and citywide infections

Water Research, Journal Year: 2023, Volume and Issue: 231, P. 119648 - 119648

Published: Jan. 20, 2023

Language: Английский

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Averting an Outbreak of SARS-CoV-2 in a University Residence Hall through Wastewater Surveillance

Microbiology Spectrum, Journal Year: 2021, Volume and Issue: 9(2)

Published: Oct. 7, 2021

A wastewater surveillance program targeting a university residence hall was implemented during the spring semester 2021 as proactive measure to avoid an outbreak of COVID-19 on campus. Over period 7 weeks from early February through late March 2021, originating collected grab samples 3 times per week. During this time, there no detection SARS-CoV-2 by reverse transcriptase quantitative PCR (RT-qPCR) in stream. Aiming obtain sample more representative community, decision made use passive samplers beginning onwards. Adopting Moore swab approach, detected just 2 days after were deployed. These also tested positive for B.1.1.7 (Alpha) variant concern (VOC) using RT-qPCR. The result triggered public health case-finding response, including mobile testing unit deployed following day, with nearly 200 students and staff, which identified two laboratory-confirmed cases Alpha COVID-19. individuals relocated separate quarantine facility, averting Aggregating clinical data, campus has yielded first estimates fecal shedding rates VOC nonclinical setting. IMPORTANCE Among adopters monitoring have been colleges universities throughout North America, many whom are approach monitor congregate living facilities evidence infection integral component screening programs. Yet, while numerous examples where among community members, few response that may averted actual outbreak. This report details wastewater-testing when mounting globally over emergence variants concern, reported be transmissible than wild-type Wuhan strain. In communication, we present clear example how resulted actionable responses administration health,

Language: Английский

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Passive sampling to scale wastewater surveillance of infectious disease: Lessons learned from COVID-19

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 835, P. 155347 - 155347

Published: April 21, 2022

Much of what is known and theorized concerning passive sampling techniques has been developed considering chemical analytes. Yet, historically, biological analytes, such as Salmonella typhi, have collected from wastewater via with Moore swabs. In response to the COVID-19 pandemic, re-emerging a promising technique monitor SARS-CoV-2 RNA in wastewater. Method comparisons disease surveillance using composite, grab, for detection found variety materials routinely produced qualitative results superior grab samples useful sub-sewershed COVID-19. Among individual studies, concentrations derived samplers demonstrated heterogeneous correlation paired composite ranging weak (R2 = 0.27, 0.31) moderate 0.59) strong 0.76). sampler materials, electronegative membranes shown great promise linear uptake observed exposure durations 24 48 h several cases positivity on par samples. Continuing development methods infectious diseases diverse forms fecal waste should focus optimizing efficient recovery kit-free extraction, resource-efficient testing capable rapidly producing or quantitative data. With refinements could prove be fundamental tool scaling disease, especially among 1.8 billion persons living low-resource settings served by non-traditional collection infrastructure.

Language: Английский

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Comparison of high-frequency in-pipe SARS-CoV-2 wastewater-based surveillance to concurrent COVID-19 random clinical testing on a public U.S. university campus

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 820, P. 152877 - 152877

Published: Jan. 6, 2022

Language: Английский

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