Foods,
Journal Year:
2023,
Volume and Issue:
12(10), P. 1989 - 1989
Published: May 14, 2023
The
occurrence
of
bisphenol
A
(BPA)
and
its
structural
analogs,
known
as
endocrine
disruptors
is
widely
reported.
Consumers
could
be
exposed
to
these
chemicals
through
canned
foods,
leading
health
risks.
Considerable
advances
have
occurred
in
the
pathogenic
mechanism,
migration
law,
analytical
methodologies
for
compounds
foods.
However,
confusion
controversies
on
sources,
migration,
impacts
plagued
researchers.
This
review
aimed
provide
insights
perspectives
effects
human
health,
surveillance
food
products.
Current
trends
determination
BPA
analogs
focused
mass
spectroscopy
electrochemical
sensor
techniques.
Several
factors,
including
pH,
time,
temperature,
volume
headspace
affect
chemicals.
Moreover,
it
necessary
quantify
proportion
them
originating
from
can
material
used
product
manufacturing.
In
addition,
adverse
reaction
research
about
exposure
low
doses
combined
with
other
contaminants
will
required.
We
strongly
believe
that
information
presented
this
paper
assist
highlighting
needs
foods
future
risk
evaluations.
Frontiers in Nutrition,
Journal Year:
2022,
Volume and Issue:
9
Published: Nov. 3, 2022
Bisphenol
A
(BPA)
is
a
synthetic
chemical
widely
employed
to
synthesize
epoxy
resins,
polymer
materials,
and
polycarbonate
plastics.
BPA
abundant
in
the
environment,
i.e.,
food
containers,
water
bottles,
thermal
papers,
toys,
medical
devices,
etc.,
incorporated
into
soil/water
through
leaching.
Being
potent
endocrine
disrupter,
has
potential
alter
several
body
mechanisms.
Studies
confirmed
its
anti-androgen
action
estrogen-like
effects,
which
impart
many
negative
health
impacts,
especially
on
immune
system,
neuroendocrine
process,
reproductive
mechanism.
Moreover,
it
can
also
induce
mutagenesis
carcinogenesis,
as
per
recent
scientific
research.
This
review
focuses
BPA's
presence
concentrations
different
environments,
sources
basic
mechanisms
of
BPA-induced
toxicity
disruptions.
It
unique
type
because
association
cancer,
hormonal
disruption,
immunosuppression,
infertility
with
BPA.
These
issues
are
widespread
today,
significantly
contributes
their
incidence
wide
usage
daily
life
utensils
other
accessories.
The
discusses
researched-based
measures
cope
toxic
chemical.
Environment International,
Journal Year:
2023,
Volume and Issue:
181, P. 108294 - 108294
Published: Oct. 28, 2023
Phthalates
and
bisphenol
A
(BPA)
are
compounds
widely
used
as
raw
materials
in
the
production
of
plastics,
making
them
ubiquitous
our
daily
lives.
This
results
widespread
human
exposure
health
hazards.
Although
efforts
have
been
conducted
to
evaluate
risk
these
diverse
regions
around
world,
data
scattering
may
mask
important
trends
that
could
be
useful
for
updating
current
guidelines
regulations.
study
offers
a
comprehensive
global
assessment
levels
chemicals,
considering
dietary
nondietary
ingestion,
evaluates
associated
risk.
Overall,
intake
(EDI)
values
phthalates
BPA
reported
worldwide
ranged
from
1.11
×
10−7
3
700
µg
kg
bw−1
d−1
3.00
10−5
6.56
d−1,
respectively.
Nevertheless,
dose-additive
effect
has
shown
increase
EDI
up
5
100
representing
high
terms
noncarcinogenic
(HQ)
carcinogenic
(CR)
effects.
The
HQ
2.25
3.66
2.74
9.72
10−2,
Meanwhile,
significant
number
studies
exhibit
CR
benzyl
butyl
phthalate
(BBP)
di(2-ethylhexyl)
(DEHP).
Moreover,
DEHP
highest
maximum
mean
humans
numerous
studies,
179-fold
higher
than
BBP.
Despite
mounting
evidence
harmful
effects
chemicals
at
low-dose
on
animals
humans,
most
regulations
not
updated.
Thus,
this
article
emphasizes
need
public
policies
compelling
adverse
exposure,
it
cautions
against
use
alternative
plasticizers
substitutes
because
gaps
their
safety.
Analytical Chemistry,
Journal Year:
2023,
Volume and Issue:
95(8), P. 4220 - 4226
Published: Feb. 14, 2023
Bisphenol
A
(BPA),
one
of
the
most
abundantly
produced
endocrine
disrupting
chemicals,
is
widely
used
in
everyday
plastic
products
and
thus
must
be
monitored.
Multimode
sensing
platforms
are
able
to
combine
advantages
different
strategies
while
solving
issues
inaccurate
test
results
single
signal
sensing.
However,
exploration
this
field
limited
due
compromise
conditions
inevitable
mutual
interferences
systems.
Herein,
we
constructed
a
two-dimensional
photonic
crystal
dually
cross-linked
supramolecular
hydrogel
(2DPCDCSH)
by
utilizing
host-guest
pair
β-cyclodextrin
(β-CD)
tert-butyl
(t-Bu)
as
second
cross-linking
for
colorimetric
fluorescent
dual-mode
BPA.
Based
on
fact
that
BPA
can
act
competitive
guest
break
interaction
between
β-CD
t-Bu,
density
decreased
an
expansion-induced
structural
color
change
occurred.
Sensitive
selective
detection
easily
achieved
measuring
Debye
diffraction
ring
diameter
or
observing
2DPC
with
limit
1
μg
mL-1.
Moreover,
formation
β-CD/BPA
complex
gave
significant
enhancement
intrinsic
fluorescence
BPA,
obtaining
0.001
The
two
systems
share
same
reaction
condition
yield
wider
dynamic
response
range
than
strategy.
Overall,
proposed
method
presented
efficient,
rapid,
cost-effective,
regenerative
analysis
shed
new
insights
design
diversified
platforms.
Best Practice & Research Clinical Obstetrics & Gynaecology,
Journal Year:
2023,
Volume and Issue:
88, P. 102347 - 102347
Published: May 6, 2023
Endocrine
Disrupting
Compounds
or
Chemicals
(EDCs)
constitute
an
extensive
and
varied
group
of
mostly
non-natural
chemicals
that
have
the
ability
to
imitate
any
aspect
hormone
action,
perturbing
many
physiological
functions
in
humans
animals.
As
for
female
fertility,
several
EDCs
are
associated
with
adverse
effects
regulation
steroidogenesis,
higher
miscarriage
rates
as
well
lower
fertilization
embryo
implantation
some
them
considered
decrease
number
high-quality
embryos
assisted
reproductive
technology
(ART)
pregnancy.
The
most
common
pesticides,
hexachlorobenzene
(HCB),
hexachlorocyclohexane
(HCH)
especially
phthalates
bisphenols
which
used
thousands
products
plasticizers.
Among
all,
Bisphenol
A
(BPA)
is
one
permeating
well-studied
EDCs.
BPA's
action
resembles
estradiol
affecting
negatively
system
various
ways.
This
review
summarizes
recent
literature
on
impact
fertility.
International Journal of Molecular Sciences,
Journal Year:
2025,
Volume and Issue:
26(2), P. 814 - 814
Published: Jan. 19, 2025
Bisphenol
A
(BPA)
is
a
prevalent
environmental
contaminant
found
in
plastics
and
known
for
its
endocrine-disrupting
properties,
posing
risks
to
both
human
health
the
environment.
Despite
widespread
presence,
impact
of
BPA
on
papillary
thyroid
cancer
(PTC)
progression,
especially
under
realistic
conditions,
not
well
understood.
This
study
examined
effects
PTC
using
3D
tumor
spheroid
model,
which
better
mimicked
complex
interactions
within
tissues
compared
traditional
2D
models.
Our
findings
demonstrated
that
BPA,
at
environmentally
relevant
concentrations,
could
induce
significant
changes
cells,
including
decrease
E-cadherin
expression,
an
increase
vimentin
reduced
thyroglobulin
(TG)
secretion.
These
suggest
exposure
may
promote
epithelial–mesenchymal
transition
(EMT),
enhance
invasiveness,
reduce
cell
differentiation,
potentially
complicating
treatment,
by
increasing
resistance
radioiodine
therapy.
research
highlights
BPA’s
hazardous
nature
as
emphasizes
need
advanced
vitro
models,
like
spheroids,
assess
posed
such
chemicals.
It
provides
valuable
insights
into
implications
role
enhancing
our
understanding
Gels,
Journal Year:
2025,
Volume and Issue:
11(3), P. 180 - 180
Published: March 5, 2025
The
comonomer
bisphenol
A
(BPA)
finds
applications
in
the
plastics
industry,
where
it
is
used
production
of
polycarbonates,
plastics,
PVC,
thermal
paper,
epoxy
and
vinyl
ester
resins,
polyurethane.
water,
with
which
many
these
materials
come
into
contact,
one
main
sources
human
exposure
to
BPA.
When
ingested
or
touched,
BPA
can
damage
organs,
disrupt
endocrine
immune
systems,
generate
inflammatory
responses,
be
involved
genotoxic
processes.
Therefore,
need
develop
effective
techniques
for
removing
from
aqueous
environments
imperative.
This
paper
provides
a
comprehensive
review
regarding
removal
focusing
on
performance
adsorption
mechanisms
various
adsorbents
based
chitosan
composites.
chemical
physical
factors,
kinetics
models
governing
process
are
also
examined.
outlines
that,
despite
considerable
progress
absorption
using
gels,
further
research
necessary
assess
efficacy
treating
real
wastewater
large-scale
manufacture.
