Data driven performance prediction of titanium-based matrix composites DOI Creative Commons
Xiaoling Wu, Yunfeng Zhou, Jinxian Zhang

et al.

Alexandria Engineering Journal, Journal Year: 2023, Volume and Issue: 85, P. 300 - 306

Published: Nov. 23, 2023

Titanium matrix composites (TMCs) offer superior specific mechanical properties compared to monolithic alloys. However, the complex interdependent effects of composition and processing on resulting microstructure make experimental determination optimal TMC formulations challenging. This work explored a materials informatics approach integrating machine learning (ML) modeling with targeted fabrication characterization for accelerated data-driven design TMCs. A dataset 368 data points composition, method various TMCs was compiled from literature. Five ML regression algorithms were implemented predict density, hardness strength composition-processing features. Among models, random forest achieved highest accuracy R2 scores above 0.93 low errors. Fabrication Ti-6Al-4 V/SiC using ML-guided parameters showed excellent agreement between predicted experimentally measured properties. The models outperformed conventional empirical predictions by structure-property linkages data. integrated computational-experimental framework can guide rapid identification property-optimized reducing trial-and-error. Further should focus physics-based feature engineering active learning. demonstrated here shows promise accelerating development high-performance

Language: Английский

The Horizons of Medical Mineralogy: Structure-Bioactivity Relationship and Biomedical Applications of Halloysite Nanoclay DOI
Yue Feng, Xiangyu Chen, Rong‐Rong He

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: 18(31), P. 20001 - 20026

Published: July 17, 2024

Medical mineralogy explores the interactions between natural minerals and living organisms such as cells, tissues, organs develops therapeutic diagnostic applications in drug delivery, medical devices, healthcare materials. Many (especially clays) have been recognized for pharmacological activities potential. Halloysite clay (Chinese medicine name: Chishizhi), manifested one-dimensional aluminum silicate nanotubes (halloysite nanotubes, HNTs), has gained hemostasis, wound repair, gastrointestinal diseases, tissue engineering, detection sensing, cosmetics, daily chemicals formulations. Various biomedical of HNTs are derived from hollow tubular structures, high mechanical strength, good biocompatibility, bioactivity, unique surface characteristics. This nanomaterial is safe, abundantly available, may be processed with environmentally safe green chemistry methods. review describes structure physicochemical properties relative to bioactivity. We discuss area, porosity defects, hydrophilicity, heterogeneity charge external internal surfaces, well biosafety. The paper provides comprehensive guidance development this tubule nanoclay its advanced clinical diagnosis therapy.

Language: Английский

Citations

16
Exploring the potential of ionic liquid-based electrochemical biosensors for real-time biomolecule monitoring in pharmaceutical applications: From lab to life DOI Creative Commons
Abhinay Thakur, Ashish Kumar

Results in Engineering, Journal Year: 2023, Volume and Issue: 20, P. 101533 - 101533

Published: Oct. 21, 2023

Ionic liquid-based electrochemical biosensors have recently surged to prominence as an intriguing technology with transformative potential for real-time biomolecule monitoring, notably within the dynamic pharmaceutical landscape. By demonstrating their adeptness in detecting extensive array of biomolecules, encompassing glucose, hormones, nucleic acids, and pivotal biomarkers, these substantiated efficacy monitoring biomolecules sphere revealing excellent thermal stability, minimal volatility, expansive working range. For instance, biosensor comprising a conducting polymer, graphene, gold nanoparticles, ionic liquids exhibited exceptional sensitivity, limit detection low 1 fM (at S/N = 3), range 3.2 0.32 pM, remarkable long-term durability aflatoxin B1 detection. In light compelling developments, first time, this review offers comprehensive exploration recent advancements emergent trajectories (spanning majorly from 2019 2023) utilization biosensors, particularly context aforementioned diverse pertinent industry. Furthermore, it discusses challenges opportunities that lie ahead production shedding on reshape future applications.

Language: Английский

Citations

26
Advances in nanocomposites-based electrochemical biosensors for the early diagnosis of breast cancer DOI Creative Commons

Osman Gamal,

Mariam Hossam Eldin,

Aya A. Refaat

et al.

Frontiers in Sensors, Journal Year: 2024, Volume and Issue: 5

Published: May 30, 2024

Regardless of many years research work and conducting numerous clinical studies, breast cancer (BC) continues to grow among women, threatening their lives future. Currently, it affects more than 10% women globally. Therefore, researchers have recently redirected endeavors toward detecting BC at an early stage, recognizing its substantial impact on survival rates, acknowledging immense potential for providing effective treatments this diagnosed disease stage. The utilization biomarker-based diagnostic techniques significantly contributes the advancement detection precision. A wide range biomarkers is linked every newly case. Traditionally, was using a variety such as mammography, molecular imaging, ultrasonography. These had several drawbacks, drawing attention scientists developing new methods strategies. Among these strategies, electrochemical biosensors proven be excellent alternatives complex traditional strategies in terms performance, accuracy, robustness, tremendous applications. In review, use conventional well challenges shortcomings been stated. Moreover, deep discussion given developed nanocomposite-based bio-sensing approaches that exploited quantification biomarkers.

Language: Английский

Citations

6
The effects of titanium dioxide nanoparticles on cadmium bioaccumulation in ramie and its application in remediation of cadmium-contaminated soil DOI Creative Commons

Huifen Deng,

Hong Lei,

Yang Luo

et al.

Alexandria Engineering Journal, Journal Year: 2023, Volume and Issue: 86, P. 663 - 668

Published: Dec. 15, 2023

Cadmium (Cd) is a toxic heavy metal contaminant in agricultural soils. Phytoremediation using hyperaccumulator plants promising remediation strategy. This study investigated the effects of TiO2 NPs on Cd uptake and accumulation ramie (Boehmeria nivea L.) grown Cd-spiked soil. The aim was to evaluate potential application enhance phytoextraction efficiency for removing from contaminated Ramie cultivated soil spiked with 5 mg/kg Cd, or without 500 NPs. results showed significantly increased concentrations roots, stems, leaves by 35%, 75%, 278% respectively, compared control plants. levels reached 146 roots 102 bioconcentration factor rose 21.6 29.2 translocation 0.3 0.7 nanoparticles. indicates bioavailability shoots. higher accumulation, especially leaves, demonstrates improve ramie's capacity. With NP treatment, decreased an estimated 20–30% after 8 weeks cultivation, indicating enhanced phytoextraction. provides evidence that can phytoremediation like Cd-contaminated

Language: Английский

Citations

15
Study on tetracycline degradation in wastewater based on zero-valent nano iron assisted micro-nano bubbles DOI Creative Commons
Changbiao Chi, Buqing Huo,

Zedong Liang

et al.

Alexandria Engineering Journal, Journal Year: 2023, Volume and Issue: 86, P. 577 - 583

Published: Dec. 14, 2023

The presence of antibiotics in wastewater has become a significant concern due to their potential environmental impact and contribution antibiotic resistance. In this study, we investigated the degradation tetracycline, commonly used antibiotic, using system based on zero-valent nano iron assisted micro-nano bubbles (MB/nZVI). synthesized nZVI-BC composite, consisting particles loaded onto phosphoric acid-activated biochar, served as an efficient adsorbent for tetracycline removal. Our findings revealed that combination MBs nZVI significantly enhanced efficiency tetracycline. MB/nZVI exhibited highest removal rate 82.81% after 2 h reaction, surpassing performance MB alone, conventional bubble (CB)/nZVI-BC systems. Furthermore, showed superior at dosage 25 g/L flow 30 mL/min. pH condition had no effect system. results demonstrate use be sustainable approach remediation tetracycline-contaminated wastewater.

Language: Английский

Citations

14
Biosensors for detection of hormones and growth factors DOI
Vahid Reza Askari, Mohammad Reza Fadaei, Vahid Tayebi Khorrami

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 181 - 213

Published: Jan. 1, 2025

Language: Английский

Citations

0
HER-2-Targeted Electrochemical Sensors for Breast Cancer Diagnosis: Basic Principles, Recent Advancements, and Challenges DOI Creative Commons

Leila Kudreyeva,

Fatima Kanysh,

Aliya Sarsenbayeva

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(4), P. 210 - 210

Published: March 25, 2025

In this literature review, methods for the detection of breast cancer biomarkers and operation electrochemical sensors are considered. The work in determination was systematized, a comparative table with other compiled, as classification depending on their intended use. various traditional diagnosis described, including mammography, ultrasound, magnetic resonance imaging, positron emission computed tomography, single-photon biopsy, advantages disadvantages presented. Key sensor parameters compared, such limit, linear range, response time, sensitivity, characteristics analyte being analyzed. Based reviewed scientific papers, significance detecting is demonstrated. types tumor identified by biosensors were analyzed, particular focus HER2. Studies HER2 using compared features determining biomarker characterized. Possible interfering agents affecting accuracy under experimental conditions considered, mechanisms action ways to eliminate them proposed. This report provides summary current aspects research biomarkers. development opens up new prospects early prognosis treatment.

Language: Английский

Citations

0
A novel magnetic FSM-16 supported ionic liquid/Pd complex as a high performance and recyclable catalyst for the synthesis of pyrano[3,2-c]chromenes DOI Creative Commons

Azar Jahanbakhshi,

Mahnaz Farahi

RSC Advances, Journal Year: 2024, Volume and Issue: 14(23), P. 16401 - 16410

Published: Jan. 1, 2024

In this work, Fe 3 O 4 @FSM-16/IL-Pd was successfully designed and synthesized via a new procedure of palladium( ii ) complex immobilization onto magnetic FSM-16 using an ionic liquid, as novel heterogeneous nanocatalyst.

Language: Английский

Citations

3
Synergistic signal amplification for HER2 biosensing using tetrahedral DNA nanostructures and 2D transition metal carbon/nitride@Au composites via ARGET ATRP DOI

Xiaohua He,

Wei Zhang, Yilong Wang

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112029 - 112029

Published: Oct. 1, 2024

Language: Английский

Citations

3
Sandwich-type supersensitive electrochemical aptasensor of glypican-3 based on PrGO-Hemin-PdNP and AuNP@PoPD DOI
Guiyin Li, Fei Guo,

Jianlu Liang

et al.

Microchimica Acta, Journal Year: 2024, Volume and Issue: 191(6)

Published: May 24, 2024

Language: Английский

Citations

2