Advantages and therapeutic applications of different semisolids as vehicles for nano-based systems DOI
Eman Samy Shalaby, S. I. Shalaby, Shaymaa A. Ismail

et al.

Therapeutic Delivery, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 11

Published: March 21, 2025

The aim of this review is to highlight the role semisolid systems as vehicles for nanovesicles and nanoparticles. In general, nanotechnology plays a critical in facilitating delivery therapeutic agents their active sites, several nanocarrier have been explored topical administration components. major disadvantage prepared nanosystems low viscosity, which reduces time needed enough absorption negatively affects stability bioavailability. overcome limitation. conclusion, presents an updated summary recent advances use semisolids various through comprehensive scrutiny types advantages enhancing nanoparticles nanovesicles.

Language: Английский

Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings DOI Creative Commons

A. S. Alberts,

Dana-Ionela Tudorache,

Adelina-Gabriela Niculescu

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 123 - 123

Published: Feb. 7, 2025

Recent advancements in wound dressing materials have significantly improved acute and chronic management by addressing challenges such as infection control, moisture balance, enhanced healing. Important progress has been made, especially with hydrogels, foams, antimicrobial for creating optimized dressings. Hydrogels are known maintaining optimal levels, while foam dressings excellent exudate absorbents. Meanwhile, incorporates various agents to reduce risks. These options healing time focusing on customized patient needs. Therefore, this review highlights the newest research prototypes applications, emphasizing their particular benefits clinical importance. Innovations stimuli-responsive hydrogels hybrid bioengineered composites discussed relation properties, including responsiveness pH, temperature, glucose, or enzymes drug delivery precision. Moreover, ongoing trials included, demonstrating potential of emerging solutions be soon translated from laboratory settings. By discussing interdisciplinary approaches that integrate advanced materials, nanotechnology, biological insights, work provides a contemporary framework patient-centric, efficient care strategies.

Language: Английский

Citations

7
Chondroitin Sulfate: An Ideal Biomaterial based Scaffolds for Cartilage Regeneration and Its Therapeutic Potential DOI Creative Commons
S. Ahmad, Huma Hameed, Sami A. Al‐Hussain

et al.

Carbohydrate Polymer Technologies and Applications, Journal Year: 2025, Volume and Issue: unknown, P. 100742 - 100742

Published: March 1, 2025

Language: Английский

Citations

0
Polydopamine Nanoparticle-Loaded Antifreezing and Photothermal Organohydrogel Based on Pullulan for Frostbite Therapy DOI

Wenzhuang Cui,

Ying Yue,

Yujie Liu

et al.

ACS Biomaterials Science & Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: March 17, 2025

Rapid rewarming is the standard and most common strategy for treating frostbite. Due to freezing susceptibility lack of thermal effects, traditional therapeutic hydrogels are not suitable being directly applied frostbite therapy in cold conditions. Contrastively, antifreezing photothermal that apt freeze capable wounds deemed hold great application potential such therapy. Nevertheless, these have rarely been researched. Herein, using glycerol as cryoprotectant polydopamine nanoparticles (PDA NPs) agent, a novel pullulan-based organohydrogel (CPG-PDA organohydrogel) was successfully developed treat first time. The CPG-PDA formed through 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide hydrochloride (EDC·HCl)-mediated esterification reactions found possess certain mechanical stability, shear-thinning behaviors (injectability), excellent properties, superb vitro vivo performances, outstanding cytocompatibility hemocompatibility. Most noticeably, coating observed significantly accelerate healing rats. opined be promising platform direct treatment environment would open new avenue design strategies

Language: Английский

Citations

0
Preparation of an antibacterial, injectable, thermosensitive, and physically cross-linked hemostatic hydrogel based on quaternized linetype poly(N-isopropylacrylamide) DOI

Yaozhen Yang,

Xue Wang,

Wenzheng Zhai

et al.

Journal of Materials Chemistry B, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

An antibacterial, injectable, thermosensitive, and physically cross-linked hemostatic hydrogel was prepared based on quaternized linetype poly( N -isopropylacrylamide), hyaluronic acid gelatin.

Language: Английский

Citations

0
Advantages and therapeutic applications of different semisolids as vehicles for nano-based systems DOI
Eman Samy Shalaby, S. I. Shalaby, Shaymaa A. Ismail

et al.

Therapeutic Delivery, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 11

Published: March 21, 2025

The aim of this review is to highlight the role semisolid systems as vehicles for nanovesicles and nanoparticles. In general, nanotechnology plays a critical in facilitating delivery therapeutic agents their active sites, several nanocarrier have been explored topical administration components. major disadvantage prepared nanosystems low viscosity, which reduces time needed enough absorption negatively affects stability bioavailability. overcome limitation. conclusion, presents an updated summary recent advances use semisolids various through comprehensive scrutiny types advantages enhancing nanoparticles nanovesicles.

Language: Английский

Citations

0