Ethnopharmacological uses, phytochemistry, pharmacological activities and toxicity of Justicia adhatoda L.: a review DOI Creative Commons
Udyanee Jayaweera, Naveen Kumar Hawala Shivashekaregowda,

S.K.M.K. Herapathdeniya

et al.

Discover Plants., Journal Year: 2024, Volume and Issue: 1(1)

Published: Nov. 25, 2024

Abstract Justicia adhatoda L. ( J. L.) belongs to the family of Acanthaceae and is a well-known medicinal plant in South Southeast Asia. The phytochemicals isolated from include alkaloids, flavonoids, phenolic acids, triterpenoids, steroids glycoside derivatives that are responsible for its diverse properties. information was obtained literature, sources including books, research papers, review papers reports available online accepted scientific databases such as Science Direct, Taylor Francis, Frontiers, Scopus, Springer, MDPI, MEDLINE, Pubmed, Wiley. This presents up-to-date data on After careful consideration, total 98 articles were used this review. Herbal medicine form healthcare has been years many countries. one multipurpose with uses, health benefits, bioactivities. Several studies revealed presence approximately 233 phytochemical constituents. Abundance these bioactive confer various pharmacological activities anti-microbial activity, antioxidant anti-inflammatory antipyretic insecticidal properties, hepatoprotective anti-diabetic anti-tubercular anti-cancer radioprotective anti-ulcer activity against respiratory ailments. provides an overview traditional phytochemistry, toxicology For future drug design discovery more screening structure–activity relationship required explore further. present brings forth current findings but there still certain aspects limited, not reliable, or lacking data. Also need be development methods isolate active compounds other parts than leaves study their potential.

Language: Английский

Botanical Flavonoids: Efficacy, Absorption, Metabolism and Advanced Pharmaceutical Technology for Improving Bioavailability DOI Creative Commons
Lei Hu, Yongming Luo, Jiaxin Yang

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(5), P. 1184 - 1184

Published: March 6, 2025

Flavonoids represent a class of natural plant secondary metabolites with multiple activities including antioxidant, antitumor, anti-inflammatory, and antimicrobial properties. However, due to their structural characteristics, they often exhibit low bioavailability in vivo. In this review, we focus on the vivo study flavonoids, particularly effects gut microbiome common modifications such as methylation, acetylation, dehydroxylation, etc. These aim change characteristics original substances enhance absorption bioavailability. order improve discuss two feasible methods, namely dosage form modification chemical modification, hope that these approaches will offer new insights into application flavonoids for human health. article, also introduce types, sources, efficacy flavonoids. conclusion, is comprehensive review how

Language: Английский

Citations

5
Chemical, microbial, and functional characterization of a new fruity probiotic kombucha DOI

Thiago Okagawa Silva,

Giselle Nobre Costa, Marcos dos Santos Lima

et al.

Food Research International, Journal Year: 2024, Volume and Issue: 198, P. 115398 - 115398

Published: Nov. 18, 2024

Language: Английский

Citations

3
Paraprobiotics and Postbiotics from the Probiotic Streptococcus lutetiensis Isolated from Indian Fermented Food Demonstrates Immunomodulatory Potential DOI Creative Commons
Jeet P. Mehta, P. Sahoo, Sonal Ayakar

et al.

The Microbe, Journal Year: 2025, Volume and Issue: unknown, P. 100304 - 100304

Published: March 1, 2025

Language: Английский

Citations

0
Enzymatic hydrolysis of anthocyanin glycosides by Bifidobacterium infantis cell-free enzymes: Stability assessment and bioavailability implications DOI Open Access

Mimoza Basholli Salihu,

Aida Shala, Toskë L. Kryeziu

et al.

Journal of Research in Pharmacy, Journal Year: 2025, Volume and Issue: 29(2), P. 486 - 496

Published: Feb. 6, 2025

The bioavailability of anthocyanins is crucial for conveying their health benefits, but they are poorly absorbed in the gastrointestinal tract (GIT). deglycosylation key step improving and bioactivity. This study investigated potential β-glucosidase β-galactosidase cell-free enzymes from Bifidobacterium infantis, on glycolytic hydrolysis essential anthocyanins, including Cyanidin-3-O-β-D-glucoside (C3-Glu), Malvidin-3- O-β-D-glucoside (M3-Glu), Cyanidin-3-O-β-D-galactoside (C3-Gal) Delphinidin-3-O-β-D-glucoside (D3-Glu). According to our previous work, infantis (B. infantis) was chosen this due its high β- glucosidase activity. anthocyanin glycosides' stability also evaluated distinguish chemical instability enzymatic degradation. B. exerted highest activity toward C3-Glu, forming levels protocatechuic acid as an active compound, with lower hydrolytic rates observed M3-Glu. Additionally, infantis's efficient against C3-Gal. study, prefers cyanidin glucoside galactoside substrates. Under experimental circumstances, delphinidin exhibited stability, malvidin glycosides similar stability. In conclusion, cause delphinidin's rate these results, may be utilized a probiotic supplement improve advantages meals supporting development functional foods medicinal formulations.

Language: Английский

Citations

0
Fermentation of Amazonian fruit pulp (bacaba) with distinct probiotics: Impacts on chemical composition, bioaccessibility, and effects on human intestinal microbiota DOI

Bianca Beatriz Torres de Assis,

Lucélia Cabral, Francyeli Araújo Silva

et al.

Food Research International, Journal Year: 2025, Volume and Issue: 209, P. 116326 - 116326

Published: April 4, 2025

Language: Английский

Citations

0
Development and characterization of sustainable chitosan film enriched with ashwagandha extract as an alternative packaging material for enhancing shelf life of fresh-cut fruits DOI Creative Commons

Mohamed Gouda,

Nashi K. Alqahtani, Manal F. Abou Taleb

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(16), P. 12472 - 12493

Published: Jan. 1, 2025

This study aimed to develop biodegradable chitosan (Cs) films enriched with Ashwagandha (ASH) extract as an active packaging material extend the shelf life of fresh-cut strawberries.

Language: Английский

Citations

0
In-situ phenolics enrichment of Camellia oleifera Abel oil via novel aqueous enzymatic extractions and its potential mechanism DOI
Linlin Liu, Chengyu Jin,

Yuanchao Lu

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: 487, P. 144663 - 144663

Published: May 14, 2025

Language: Английский

Citations

0
From extract to crystals: Unlocking green nanotechnology towards recovery of bioactive compounds from Moringa oleifera via membrane distillation crystallization DOI Creative Commons
Lebea N. Nthunya,

Boitumelo Setati,

Heidi Richards

et al.

Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 133552 - 133552

Published: May 1, 2025

Language: Английский

Citations

0
Formulation and Characterization of Ready-To-Drink Nutraceutical Beverage from blood fruit (Haematocarpus validus) DOI Creative Commons
Raju Sasikumar,

T. Selva Kumar,

Kambhampati Vivek

et al.

LWT, Journal Year: 2025, Volume and Issue: unknown, P. 117929 - 117929

Published: May 1, 2025

Language: Английский

Citations

0
Ethnopharmacological uses, phytochemistry, pharmacological activities and toxicity of Justicia adhatoda L.: a review DOI Creative Commons
Udyanee Jayaweera, Naveen Kumar Hawala Shivashekaregowda,

S.K.M.K. Herapathdeniya

et al.

Discover Plants., Journal Year: 2024, Volume and Issue: 1(1)

Published: Nov. 25, 2024

Abstract Justicia adhatoda L. ( J. L.) belongs to the family of Acanthaceae and is a well-known medicinal plant in South Southeast Asia. The phytochemicals isolated from include alkaloids, flavonoids, phenolic acids, triterpenoids, steroids glycoside derivatives that are responsible for its diverse properties. information was obtained literature, sources including books, research papers, review papers reports available online accepted scientific databases such as Science Direct, Taylor Francis, Frontiers, Scopus, Springer, MDPI, MEDLINE, Pubmed, Wiley. This presents up-to-date data on After careful consideration, total 98 articles were used this review. Herbal medicine form healthcare has been years many countries. one multipurpose with uses, health benefits, bioactivities. Several studies revealed presence approximately 233 phytochemical constituents. Abundance these bioactive confer various pharmacological activities anti-microbial activity, antioxidant anti-inflammatory antipyretic insecticidal properties, hepatoprotective anti-diabetic anti-tubercular anti-cancer radioprotective anti-ulcer activity against respiratory ailments. provides an overview traditional phytochemistry, toxicology For future drug design discovery more screening structure–activity relationship required explore further. present brings forth current findings but there still certain aspects limited, not reliable, or lacking data. Also need be development methods isolate active compounds other parts than leaves study their potential.

Language: Английский

Citations

1