Unraveling the flavor formation process of mellow and thick-type ripened Pu-erh tea through non-targeted metabolomics and metagenomics DOI Creative Commons

Zixi Yang,

Yongshu Xie,

Yuanmin Zhu

et al.

Food Chemistry X, Journal Year: 2025, Volume and Issue: 27, P. 102424 - 102424

Published: April 1, 2025

Ripened Pu-erh tea (RPT) is renowned for its distinctive flavor and health benefits. However, complex fermentation process poses challenges in ensuring consistency production. This study investigated RPT formation through sensory evaluation, multi-omics analysis, multivariate statistical approaches. By day 24, the exhibited a reddish-brown infusion mellow, thick taste (MT_RPT), achieving highest score (94.0, P < 0.05). Sixteen flavor-related chemical components significant changes (P The contents of free amino acids, L-theanine, polyphenols, flavonoids, catechins, thearubigins decreased. In contrast, total soluble sugars, caffeine, theobromine, epicatechin, theabrownins (TBs) increased, reaching 74.1 mg/g, 65.38 3.13 3.33 134.84 respectively. Additionally, 33 nonvolatile metabolites (e.g., pelargonidin 3-O-glucoside, dihydroisorhamnetin, puerarin) were significantly correlated with MT_RPT (VIP > 1, |r| ≥ 0.8, 0.05) influenced by key functional microbes, including Pantoea, Aspergillus, Brachybacterium, Staphylococcus. 30, darkened, scores declined (81.4, 0.05), attributed to dominance Brevibacterium. microbial shift reduced water-soluble pectin, 11 while increasing TBs theophylline (219.33 mg/g 0.09 respectively). Therefore, identified as crucial indicator optimal fermentation. Moreover, redundancy analysis indicated that pile's central temperature, moisture content, pH essential parameters These findings deepen our understanding development mechanisms provide valuable insights into precise control.

Language: Английский

Theabrownin inhibits obesity and non-alcoholic fatty liver disease in mice via serotonin-related signaling pathways and gut-liver axis DOI Creative Commons
Hangyu Li, Siyu Huang, Dan-Dan Zhou

et al.

Journal of Advanced Research, Journal Year: 2023, Volume and Issue: 52, P. 59 - 72

Published: Jan. 11, 2023

Non-alcoholic fatty liver disease (NAFLD) with obesity seriously threats public health. Our previous studies showed that dark tea had more potential on regulating lipid metabolism than other teas, and theabrownin (TB) was considered to be a main contributor the bioactivity of tea.This in vivo study aims reveal effects molecular mechanisms TB NAFLD obesity, role gut-liver axis is explored.The histopathological examinations, biochemical tests, nuclear magnetic resonance were applied evaluate obesity. The untargeted metabolomics used find key molecule for further exploration mechanisms. 16S rRNA gene sequencing assess changes gut microbiota. antibiotic cocktail fecal microbiota transplant clarify microbiota.TB markedly reduced body weight gain (67.01%), fat rate (62.81%), hepatic TG level (51.35%) preventive experiment. Especially, decreased (32.16%), (42.56%), (42.86%) therapeutic action could improvement acid oxidation, lipolysis, oxidative stress via regulation serotonin-related signaling pathways. Also, increased abundance microbiota, such as Akkermansia, Bacteroides Parabacteroides. Antibiotics-induced bacterial dysbiosis disrupted pathways liver, whereas beneficial target proteins regained restoration microbiota.We has by serotonin related through Furthermore, co-contribute alleviating promising medicine

Language: Английский

Citations

60

Pile-fermentation mechanism of ripened Pu-erh tea: Omics approach, chemical variation and microbial effect DOI
Cunqiang Ma,

Bingsong Ma,

Binxing Zhou

et al.

Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: 146, P. 104379 - 104379

Published: Feb. 17, 2024

Language: Английский

Citations

21

Quantitative descriptive analysis, non-targeted metabolomics and molecular docking reveal the dynamic aging and taste formation mechanism in raw Pu-erh tea during the storage DOI Creative Commons

Bingsong Ma,

Cunqiang Ma, Binxing Zhou

et al.

Food Chemistry X, Journal Year: 2025, Volume and Issue: unknown, P. 102234 - 102234

Published: Jan. 1, 2025

Language: Английский

Citations

3

Catabolism of polyphenols released from mung bean coat and its effects on gut microbiota during in vitro simulated digestion and colonic fermentation DOI

Jiayan Xie,

Nian X. Sun, Hairong Huang

et al.

Food Chemistry, Journal Year: 2022, Volume and Issue: 396, P. 133719 - 133719

Published: July 16, 2022

Language: Английский

Citations

58

Determination of the variations in the metabolic profile and sensory quality of Liupao tea during fermentation through UHPLC–HR–MS metabolomics DOI

Huifang Wang,

Jianwen Teng, Li Huang

et al.

Food Chemistry, Journal Year: 2022, Volume and Issue: 404, P. 134773 - 134773

Published: Oct. 29, 2022

Language: Английский

Citations

40

Dietary Plant Polysaccharides for Cancer Prevention: Role of Immune Cells and Gut Microbiota, Challenges and Perspectives DOI Open Access
Anqi Wang, Ying Liu, Shan Zeng

et al.

Nutrients, Journal Year: 2023, Volume and Issue: 15(13), P. 3019 - 3019

Published: July 3, 2023

Dietary plant polysaccharides, one of the main sources natural possess significant cancer prevention activity and potential development value in food medicine fields. The anti-tumor mechanisms polysaccharides are mainly elaborated from three perspectives: enhancing immunoregulation, inhibiting tumor cell growth invasion metastasis. immune system plays a key role progression, immunomodulation is considered pathway for or treatment. Although much progress has been made revealing relationship between huge challenges still met research polysaccharides. Results suggest that certain polysaccharide types glycosidic linkage forms significantly affect biological immunoregulation. At present, vitro effects immunoregulation dietary widely reported articles; however, vivo deserving further investigation. In this paper, aspects behind polysaccharides' achieved through cells mediatory gut microbiota systematically summarized, with aim encouraging future on use prevention.

Language: Английский

Citations

24

A cooperative combination of non-targeted metabolomics and electronic tongue evaluation reveals the dynamic changes in metabolites and sensory quality of radish during pickling DOI
Wenliang Liu, Lingyu Zhang, Emad Karrar

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 446, P. 138886 - 138886

Published: Feb. 27, 2024

Language: Английский

Citations

15

Structural characterization, molecular dynamic simulation, and conformational visualization of a water-soluble glucan with high molecular weight from Gastrodia elata Blume DOI
Jiaqian Chen,

Wen Miao,

Ying Liu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 263, P. 130207 - 130207

Published: Feb. 14, 2024

Language: Английский

Citations

13

Non-destructive prediction of tea polyphenols during Pu-erh tea fermentation using NIR coupled with chemometrics methods DOI
Min Liu,

Runxian Wang,

Delin Shi

et al.

Journal of Food Composition and Analysis, Journal Year: 2024, Volume and Issue: 131, P. 106247 - 106247

Published: April 16, 2024

Language: Английский

Citations

10

Effect of CeO2, TiO2 and SiO2 nanoparticles on the growth and quality of model medicinal plant Salvia miltiorrhiza by acting on soil microenvironment DOI Creative Commons
Ying Ren, Gang Wang, Yuying Su

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 280, P. 116552 - 116552

Published: June 8, 2024

In this study, a six-month pot experiment was conducted to explore the effects of nanoparticles (NPs), including CeO

Language: Английский

Citations

10