Antioxidant Effects and Potential Mechanisms of Citrus reticulata ‘Chachi’ Components: An Integrated Approach of Network Pharmacology and Metabolomics DOI Creative Commons
Jingfa Xiao,

Tian Sun,

Shengyu Jiang

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(24), P. 4018 - 4018

Published: Dec. 12, 2024

Citrus reticulata ‘Chachi’ (CRC), recognized for its considerable edible and medicinal significance, is a valuable source of metabolites beneficial to human health. This research investigates the metabolic distinctions antioxidant properties across four different parts CRC, using multivariate statistical analysis interpret metabolomic data network pharmacology identify potential targets relevant signaling pathways. The results indicate differences in sample, with 1622 showing differential expression, including 816 secondary metabolites, primarily consisting terpenoids (31.02%) flavonoids (25.22%). dried mature citrus peel (CP) section demonstrates highest level total phenolics (6.8 mg/g), followed by pulp without seed (PU) (4.52 (PWS) (4.26 (SE) (2.16 mg/g). Interestingly, targeted high-performance liquid chromatography reveals nobiletin tangeretin CP, whereas PU has hesperidin, narirutin, didymin. Furthermore, all sections CRC exhibit robust vitro assessments (CP > PWS SE). Lastly, uncovered mechanisms CRC. offers deeper insights into development utilization byproducts processing industry.

Language: Английский

Unveiling the mechanism of Latilactobacillus sakei LZ217 cell-free supernatant against Helicobacter pylori through metabolomics and network pharmacology DOI

Chenlan Xia,

Qingqing Zhou,

Xia Meng

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 105925 - 105925

Published: Jan. 1, 2025

Language: Английский

Citations

1

Multi-omics and Bioinformatics for the Investigation of Therapeutic Mechanism of Roucongrong Pill against Postmenopausal Osteoporosis DOI
Tao Jiang, Chenhao Li, Yufen Li

et al.

Journal of Ethnopharmacology, Journal Year: 2024, Volume and Issue: unknown, P. 118873 - 118873

Published: Oct. 1, 2024

Language: Английский

Citations

5

Rapid in situ identification of honey authenticity based on RP-Nano-ESI-MS using online desalting DOI
Wenjie Yu, Qifang Sun,

Liangliang Qu

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 458, P. 140278 - 140278

Published: June 28, 2024

Language: Английский

Citations

4

The effects and mechanisms of aqueous Persicaria capitata extract on uropathogenic Escherichia coli adhesion DOI
Yang Zhou, Zuying Zhou,

Jin Lin

et al.

Phytomedicine, Journal Year: 2025, Volume and Issue: 139, P. 156515 - 156515

Published: Feb. 14, 2025

Language: Английский

Citations

0

Higenamine protects against doxorubicin-induced heart failure by attenuating ferroptosis via modulating the Nrf2/GPX4 signaling pathway DOI
Jianxia Wen, Lu Li,

Dinglin Ou

et al.

Phytomedicine, Journal Year: 2025, Volume and Issue: unknown, P. 156670 - 156670

Published: March 1, 2025

Language: Английский

Citations

0

Dunhuang Dabupi Decoction and its active components alleviate ulcerative colitis by activating glutathione metabolism and inhibiting JAK-STAT pathway in Drosophila and mice DOI
He Li, Youming Zhang, Jiangnan Li

et al.

Journal of Ethnopharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 119717 - 119717

Published: March 1, 2025

Language: Английский

Citations

0

Unraveling microbial pathogenesis through omics technologies for better therapeutic interventions DOI Creative Commons
Ankita Sharma,

Alka Rana,

B. Pavan Kumar

et al.

The Microbe, Journal Year: 2025, Volume and Issue: unknown, P. 100347 - 100347

Published: April 1, 2025

Language: Английский

Citations

0

Integrating larval zebrafish model and network pharmacology for screening and identification of edible herbs with therapeutic potential for MAFLD: A promising drug Smilax glabra Roxb. DOI

Yinjuan Xiong,

Xixuan Huang,

Yuxin Li

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 464, P. 141470 - 141470

Published: Sept. 30, 2024

Language: Английский

Citations

3

Exploring the protection on islet β-cells and hypoglycemic effect of Moringa oleifera stem based on network pharmacology and experimental validation DOI Creative Commons

Xilin Jiang,

Jian Tang, Zhiqiang Gao

et al.

Journal of Functional Foods, Journal Year: 2024, Volume and Issue: 122, P. 106499 - 106499

Published: Oct. 9, 2024

Language: Английский

Citations

1

Insights into the microbiota of raw milk from seven breeds animals distributing in Xinjiang China DOI Creative Commons

Baolong Luo,

Fan Dong, Yuyang Liu

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 23, 2024

Owing to its high nutritional content, raw milk contains a rich microbiota. Thus, study microorganisms present in available Xinjiang China, 142 samples from seven animal breeds (cow, sheep, goat, donkey, horse, camel, and yak) four regions (Hami, Tarbagatay, Kashgar, Ili) were analyzed by high-throughput DNA sequencing. These characterized 10 dominant phyla. Proteobacteria (68.33%) was the major phylum, followed Firmicutes (18.80%) Thermi (3.16%). Horse contained more Bacteroidetes, sheep Gammaproteobacteria, donkey unclassified sequences. Camel highest lowest bacterial diversity compared with that remaining samples, respectively. Additionally, spoilage microorganisms, including Chryseobacterium , Propionibacterium Flavobacterium pathogenic bacteria, Ochrobactrum anthropi Sphingomonas prevalent horse yak milk, whereas probiotic lactic acid bacteria (LAB), such as Leuconostoc Lactococcus or Lactobacillus camel milk. Furthermore, Moraxella abundantly Acinetobacter abundant Pseudomonas relatively Overall, specific harmful found obtained different animals, which provided basis for preventing controlling growth of well investigating resources

Language: Английский

Citations

1