Journal of Agricultural and Food Chemistry,
Journal Year:
2025,
Volume and Issue:
73(6), P. 3286 - 3304
Published: Jan. 31, 2025
Astaxanthin
(AST),
as
a
natural
antioxidant,
has
broad
application
prospects
in
medicine
and
health
products.
However,
its
highly
unsaturated
structure
significant
lipophilic
characteristics
limit
dispersibility
bioavailability,
thereby
restricting
food,
medicines,
nutraceuticals.
To
overcome
these
limitations,
researchers
have
proposed
the
use
of
nano
delivery
systems.
This
review
summarizes
various
nanocarriers,
including
liposomes,
nanostructured
lipid
carriers,
nanoparticles,
others,
analyzes
their
advantages
enhancing
solubility,
stability,
bioavailability
AST.
Furthermore,
study
focuses
on
targeted
systems
achieved
through
biomolecular
modifications,
which
enable
precise
AST
to
specific
cells
or
tissues,
therapeutic
effects.
Additionally,
smart-responsive
systems,
such
pH-responsive
light-sensitive
are
also
discussed,
showing
immense
potential
release
therapy.
These
findings
provide
new
perspectives
for
nutrition
clinical
applications
Future
research
should
further
optimize
design
nanocarriers
broader
applications.
Polymers,
Journal Year:
2023,
Volume and Issue:
15(21), P. 4327 - 4327
Published: Nov. 5, 2023
In
recent
years,
there
has
been
a
growing
interest
in
the
use
of
gelatin
nanoparticles
(GNPs)
for
treatment
infectious
diseases.
The
inherent
properties
these
make
them
attractive
options
drug
delivery.
Their
biocompatibility
ensures
that
they
can
interact
with
biological
systems
without
causing
adverse
reactions,
while
their
biodegradability
break
down
harmlessly
body
once
function
is
performed.
Furthermore,
capacity
controlled
release
therapeutic
agents
be
delivered
over
sustained
period,
thereby
enhancing
efficacy.
This
review
examines
current
landscape
GNP-based
delivery,
specific
focus
on
its
potential
applications
and
challenges
context
Key
include
controlling
rates,
ensuring
nanoparticle
stability
under
physiological
conditions,
scaling
up
production
maintaining
quality,
mitigating
immunogenic
optimizing
loading
efficiency,
tracking
biodistribution
clearance
GNPs
body.
Despite
hurdles,
hold
promising
realm
disease
treatment.
Ongoing
research
innovation
are
essential
to
overcome
obstacles
completely
harness
clinical
applications.
