Advances in prebiotic carbohydrate–based targeted delivery: Overcoming gastrointestinal challenges for bioactive ingredients DOI
Yunzhen Zhang,

Jian He,

Hong Zeng

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 466, P. 142210 - 142210

Published: Nov. 26, 2024

Language: Английский

Recent Insights and Applications of Nanocarriers-Based Drug Delivery Systems for Colonic Drug Delivery and Cancer Therapy: An Updated Review DOI
Sobia Noreen, Irsah Maqbool, Azeem Saleem

et al.

Critical Reviews in Oncology/Hematology, Journal Year: 2025, Volume and Issue: unknown, P. 104646 - 104646

Published: Feb. 1, 2025

Language: Английский

Citations

0
Preparation of pH-enzyme dual-responsive gel microspheres and their treatment of ulcerative colitis DOI

Ying-Jie Geng,

Y D Li,

Haolong Qi

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 306, P. 141567 - 141567

Published: Feb. 27, 2025

Language: Английский

Citations

0
Protein/polysaccharide based oral delivery system for precise targeting of polyphenols and carotenoids DOI
Wen Jiang,

S.W. Zhai,

Li Zhu

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: unknown, P. 105311 - 105311

Published: Oct. 1, 2024

Language: Английский

Citations

2
Colon-targeted delivery of polyphenols: construction principles, targeting mechanisms and evaluation methods DOI
Yidi Wang, Zhiying Li, Yiwen Bao

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2023, Volume and Issue: unknown, P. 1 - 23

Published: Oct. 12, 2023

AbstractPolyphenols have received considerable attention for their promotive effects on colonic health. However, polyphenols are mostly sensitive to harsh gastrointestinal environments, thus, must be protected. It is necessary design and develop a colon-targeted delivery system improve the stability, colon-targeting bioavailability of polyphenols. This paper mainly introduces research controlled release The physiological features affecting dissolution, absorption polyphenol-loaded systems in colon first discussed. Simultaneously, types carriers with different mechanisms described, assessment models that been studied so far advantages limitations summarized. Based current colon-targeting, outlook reflections proposed, goal inspiring strategic development new therapeutics ensure reach complete bioactivity.Keywords: Colonic targetingpolyphenolscontrolled releaseconstruction principlesdelivery Authors' contributionsYidi Wang: Conceptualization-Equal, Data curation-Equal, Investigation-Equal, Writing – original draft; Zhiying Li: Formal analysis; Yiwen Bao: Investigation-Equal; Huijun Cui: Project administration-Equal; Jiaxin Methodology-Equal; Xingyue Resources-Equal; Mengzhu Baoge Song: Methodology-Equal, Haikun Yi Chen: Resources-Equal, Supervision-Equal; WeiChen: administration-Equal, Shufang Yang: Yiyun Zhufeng Jin: Xu Si: Funding acquisition-Equal, Software, Supervision-Equal, Validation, review & editing; Bin Supervision-Equal.Disclosure statementNo potential conflict interest was reported by author(s).Additional informationFundingThis work supported National Natural Science Foundation China [U21A20273], Central Government-guided local Technology Fund [2023JH6/100500010] Scientific Research Projects Liaoning Province [LSNQN202010].

Language: Английский

Citations

4
Exploration of the formative mechanisms of colon-targeting composite particles of natural products prepared via mechanical dry particle coating DOI
Zekai Chen, Chenyi Yuan, Weiman Hong

et al.

Advanced Powder Technology, Journal Year: 2024, Volume and Issue: 35(11), P. 104648 - 104648

Published: Sept. 30, 2024

Language: Английский

Citations

1
Construction of biopolymer-based hydrogel beads for encapsulation, retention, and colonic delivery of tributyrin: Development of functional beverages (fortified bubble tea) DOI

Gege Sun,

Bin Li, Yan Li

et al.

Food Research International, Journal Year: 2024, Volume and Issue: 197, P. 115165 - 115165

Published: Sept. 30, 2024

Language: Английский

Citations

1
Construction and characterization of a novel Myr-OSADS-CIn micelle for enhanced stability and bioavailability of myricetin DOI

Zhi-Yuan Nie,

Xueying Li, Ying‐Ying Chen

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: 60, P. 104287 - 104287

Published: May 7, 2024

Language: Английский

Citations

0
Oral responsive delivery systems for probiotics targeting the intestinal tract DOI
Mengzhen Han,

Mengxin Hou,

Shuang Yang

et al.

Journal of the Science of Food and Agriculture, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 18, 2024

Abstract The increasing prevalence of health issues, driven by sedentary lifestyles and unhealthy diets in modern society, has led to a growing demand for natural dietary supplements support overall well‐being. Probiotic have garnered widespread recognition their potential benefits. However, efficacy is often hindered the hostile conditions gastrointestinal tract. To surmount this challenge, biomaterial‐based microencapsulation techniques been extensively employed shield probiotics from harsh environments stomach acid bile salts, facilitating precise delivery colon optimal nutritional effects. With consideration distinctive tract milieu, probiotic systems categorized into pH‐responsive release, enzyme‐responsive redox‐responsive release pressure‐triggered systems. These responsive not only demonstrated improved survival rates stomach, but also successful intestines, enhanced adhesion colonization within gut. Consequently, these contribute effectiveness supplementation intervening with diseases. This review provides comprehensive overview diverse oral tailored targeting intestinal Furthermore, critically examines limitations future prospects approaches. offers valuable guidance effective tract, enhancing as promote © 2024 Society Chemical Industry.

Language: Английский

Citations

0
Development and evaluation of innovative enteric-coated capsules for colon-specific delivery of hydrophilic biomaterials DOI
Nicole Fülöpová,

Klemens Brückner,

Jan Muselík

et al.

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: unknown, P. 124991 - 124991

Published: Nov. 1, 2024

Language: Английский

Citations

0
Advances in prebiotic carbohydrate–based targeted delivery: Overcoming gastrointestinal challenges for bioactive ingredients DOI
Yunzhen Zhang,

Jian He,

Hong Zeng

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 466, P. 142210 - 142210

Published: Nov. 26, 2024

Language: Английский

Citations

0