Study on the physiological responses and tolerance mechanisms to subchronic carbonate alkalinity exposure in the gills of Paramisgurnus dabryanus DOI Creative Commons

Luojia Li,

Wei Luo,

Pengyu Chen

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 287, P. 117319 - 117319

Published: Nov. 1, 2024

Given the reduction of freshwater resources, saline-alkaline aquaculture has emerged as an effective approach to expand fishery's accessible space. High carbonate alkalinity (CA) is a major stressor for aquatic organisms in environments. Paramisgurnus dabryanus potential species culture water, making it ideal model investigating physiological responses and tolerance mechanisms CA exposure fishes. In current study, P. were exposed 15 30 mmol/L NaHCO

Language: Английский

Integration of microbiomics and metabolomics reveals energy metabolism imbalance in crucian carp (Carassius auratus) under saline-alkaline exposure DOI

Lin Han,

Wenzhi Liu,

Fangying Yuan

et al.

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Journal Year: 2025, Volume and Issue: 291, P. 110145 - 110145

Published: Feb. 20, 2025

Language: Английский

Citations

0
α-Ketoglutarate modulates the mechanisms of toxicity in crucian carp kidneys chronically exposed to NaHCO3: Metabolomics insights DOI
Wenzhi Liu,

Lin Han,

Fangying Yuan

et al.

Comparative Biochemistry and Physiology Part D Genomics and Proteomics, Journal Year: 2025, Volume and Issue: 55, P. 101466 - 101466

Published: March 4, 2025

Language: Английский

Citations

0
Transcriptional analysis reveals antioxidant, ion transport, and glycolysis mechanisms in Litopenaeus vannamei gills involved in the response to high alkali stress DOI
Yiming Li,

Yucong Ye,

Xiaoyi Zhu

et al.

Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, Journal Year: 2025, Volume and Issue: unknown, P. 111868 - 111868

Published: April 1, 2025

Language: Английский

Citations

0
Dietary Melatonin Supplementation Improved Intestinal Health and Immune Function of Pacific White Shrimp (Litopenaeus vannamei) Under High Alkali Stress DOI Creative Commons
Yiming Li,

Yucong Ye,

Haojuan Yuan

et al.

Life, Journal Year: 2025, Volume and Issue: 15(5), P. 772 - 772

Published: May 12, 2025

The intestinal tract serves as a critical immune regulator in aquatic species, maintaining homeostasis and environmental stress resistance. This study evaluates the protective effects of melatonin (MT) on Litopenaeus vannamei (L. vannamei) under acute alkaline through comprehensive analysis morphology, antioxidant responses, apoptosis regulation, microbial community dynamics. A total six groups treatment were designed. After another 2 months breeding, 96 h alkalinity experiment was conducted. Experimental supplementation revealed dose-dependent outcomes: 82.7 mg/kg MT significantly improved survival rates without affecting growth parameters, while higher concentrations (329.2 mg/kg) induced elevated (p < 0.05). Histological examination demonstrated mitigated structural damage MT-treated compared to non-supplemented controls stress. Antioxidant capacity initially increased then stabilized at optimal doses (82.7–165.1 mg/kg), accompanied by enhanced marker expression Microbial profiling indicated MT-mediated enrichment commensal bacteria associated with polysaccharide metabolism, energy utilization, immunity. establishes that exerts protection L. stress, balancing enhancement, modulation, microbiome regulation fortify health, 82.7–165.1 identified therapeutic range for mitigating compromising physiological homeostasis. results this establish an empirical framework optimizing application crustacean aquaculture, particularly highlighting its role barrier integrity challenges.

Language: Английский

Citations

0
The response mechanism of high pH and alkalinity interactive stress on immune system and energy metabolism pathway of Litopenaeus vannamei DOI

Xue Mao,

Ruiqi Zhang, Jianfu Wang

et al.

Comparative Biochemistry and Physiology Part D Genomics and Proteomics, Journal Year: 2025, Volume and Issue: unknown, P. 101531 - 101531

Published: May 1, 2025

Language: Английский

Citations

0
Changes in Physiological Homeostasis in the Gills of Litopenaeus vannamei Under Carbonate Alkalinity Stress and Recovery Conditions DOI Creative Commons

Meng Xiao,

Yuxiu Nan,

Yukai Yang

et al.

Fishes, Journal Year: 2024, Volume and Issue: 9(11), P. 463 - 463

Published: Nov. 15, 2024

Carbonate alkalinity (CA) is the major toxic factor that interferes with survival and growth of shrimp in saline–alkaline water. Gills are main entry organ for CA toxicity shrimp. In this study, low-salinity cultured Litopenaeus vannamei were exposed to 5 mmol/L stress 7 days then recovered explore physiological changes gills under recovery conditions at multiple biological levels. The results showed increased activities antioxidative biochemical indexes (T-AOC, T-SOD, POD) relative expression levels romo1, nrf2, gpx genes, while it decreased sod hsp70 genes. addition, also genes involved endoplasmic reticulum (ER) (bip, ire1, xbp1), immunity (alf, crus, pen-3, lys, propo), apoptosis (casp-3), detoxification metabolism (cyp450 gst), osmotic adjustment (ca, nka-α, nka-β, vatp, nhe, clc, aqp, tip4, ccp). Although some reversed after was relieved, they still could not effectively recover control level. These reveal has a negative impact on homeostasis by inducing oxidation ER interfering immunity, apoptosis, detoxification, adjustment.

Language: Английский

Citations

3
Study on the physiological responses and tolerance mechanisms to subchronic carbonate alkalinity exposure in the gills of Paramisgurnus dabryanus DOI Creative Commons

Luojia Li,

Wei Luo,

Pengyu Chen

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 287, P. 117319 - 117319

Published: Nov. 1, 2024

Given the reduction of freshwater resources, saline-alkaline aquaculture has emerged as an effective approach to expand fishery's accessible space. High carbonate alkalinity (CA) is a major stressor for aquatic organisms in environments. Paramisgurnus dabryanus potential species culture water, making it ideal model investigating physiological responses and tolerance mechanisms CA exposure fishes. In current study, P. were exposed 15 30 mmol/L NaHCO

Language: Английский

Citations

2