Site‐Selective Direct γ‐Difunctionalization of Diazoenals: Application to the Synthesis of Enal‐Functionalized Allenes and Furans DOI Open Access
Jagadeesh Kalepu, Bapurao Sudam Lad, Pratap Kumar Mandal

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 23, 2024

A new approach for the synthetically important γ-functionalized enals has been developed. The strategy involves rhodium-catalyzed direct C-C & C-S bond forming site-selective γ-difunctionalization of diazoenals with aryl propargyl sulfides via sulfur ylide [2,3] sigmatropic rearrangement, resulting in highly functionalized γ-allenyl(sulfanyl)enals excellent yield at ambient temperature. This versatile constitutes a viable alternative to remote carbonyl-directed γ-functionalization unmodified which suffer from competitive side reactions. synthetic utility was demonstrated by InCl

Language: Английский

Denitrogenative transformations of aryl-fused 1,2,3-triazoles DOI
Fostino R. B. Bokosi, Tasiana Reza, Sinead T. Keaveney

et al.

Advances in heterocyclic chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0
Site‐Selective Direct γ‐Difunctionalization of Diazoenals: Application to the Synthesis of Enal‐Functionalized Allenes and Furans DOI Open Access
Jagadeesh Kalepu, Bapurao Sudam Lad, Pratap Kumar Mandal

et al.

Chemistry - An Asian Journal, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 23, 2024

A new approach for the synthetically important γ-functionalized enals has been developed. The strategy involves rhodium-catalyzed direct C-C & C-S bond forming site-selective γ-difunctionalization of diazoenals with aryl propargyl sulfides via sulfur ylide [2,3] sigmatropic rearrangement, resulting in highly functionalized γ-allenyl(sulfanyl)enals excellent yield at ambient temperature. This versatile constitutes a viable alternative to remote carbonyl-directed γ-functionalization unmodified which suffer from competitive side reactions. synthetic utility was demonstrated by InCl

Language: Английский

Citations

1