Emerging challenges in antimicrobial resistance: implications for pathogenic microorganisms, novel antibiotics, and their impact on sustainability

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: April 29, 2024

Overuse of antibiotics is accelerating the antimicrobial resistance among pathogenic microbes which a growing public health challenge at global level. Higher causes severe infections, high complications, longer stays hospitals and even increased mortality rates. Antimicrobial (AMR) has significant impact on national economies their systems, as it affects productivity patients or caregivers due to prolonged hospital with economic costs. The main factor AMR includes improper excessive use antimicrobials; lack access clean water, sanitation, hygiene for humans animals; poor infection prevention control measures in hospitals; medicines vaccines; awareness knowledge; irregularities legislation. represents problem, epidemiological surveillance systems have been established, aiming promote collaborations directed well-being human animal balance ecosystem. MDR bacteria such E. coli , Staphylococcus aureus Pseudomonas aeruginosa Enterococcus spp., Acinetobacter Klebsiella pneumonia can cause death. These microorganisms variety antibiotic mechanisms, development drug-deactivating targets, alterations decrease intracellular concentration, render themselves resistant numerous antibiotics. In context, United Nations issued Sustainable Development Goals (SDGs) 2015 serve worldwide blueprint better, more equal, sustainable existence our planet. SDGs place context socioeconomic issues; also, continued growth may hinder achievement SDGs. this review, we discuss role environmental pollution rise AMR, different mechanisms underlying resistance, threats posed by microbes, novel antibiotics, strategies One Health combat sustainability goals.

Language: Английский

---

Switching heterojunction system from Type-II to S-scheme for efficient photocatalytic degradation of ciprofloxacin

Separation and Purification Technology, Journal Year: 2024, Volume and Issue: 345, P. 127323 - 127323

Published: April 1, 2024

Language: Английский

---

Comprehensive evaluation of antibiotic pollution in a typical tributary of the Yellow River, China: Source-specific partitioning and fate analysis

Journal of Hazardous Materials, Journal Year: 2025, Volume and Issue: 488, P. 137294 - 137294

Published: Jan. 20, 2025

Language: Английский

---

MXene-based composite photocatalysts for efficient degradation of antibiotics in wastewater

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Dec. 28, 2024

Abstract MXene-based (nano)materials have recently emerged as promising solutions for antibiotic photodegradation from aquatic environments, yet they are limited by scalability, stability, and selectivity challenges in practical settings. We formulated Fe 2 O 3 -SiO /MXene ternary nano-photocomposites via coupled wet impregnation sonochemistry approach optimised tetracycline (TC) removal (the second most used worldwide) water using response surface methodology-central composite design (RSM-CCD). The photocatalysts containing various loading of /SiO (5–45 wt%) on the MXene with a range calcination temperatures (300–600 °C) RSM optimisation were synthesised, characterised regarding crystallinity properties, morphology, binding energy, light absorption capability, analysed TC degradation efficiency. 25FeS/MX-450 among all samples demonstrated superior efficiency photocatalytic (98%) under conditions (TC degradation: 39.75 mg/L, time: 68.28 min, pH: 5.57, catalyst dosage: 0.75 g/L). developed area, reduced band gap due to FeS nanoparticles incorporation improved within visible spectrum, played crucial role heterostructure matrix, enhancing photogenerated carriers’ separation transportation capabilities. photoreduction mechanism involved electron transfer MXene, engaging produce •O −, attributed high mobility MXene. Our findings such materials can underscore considerable potential nanomaterials pharmaceutical waterways.

Language: Английский

---

Remediation of antibiotics using coordination polymers

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 519, P. 216120 - 216120

Published: Aug. 9, 2024

Language: Английский

---

The Convergence of Antibiotic Contamination, Resistance, and Climate Dynamics in Freshwater Ecosystems

Water, Journal Year: 2024, Volume and Issue: 16(18), P. 2606 - 2606

Published: Sept. 14, 2024

The convergence of antibiotic contamination, antimicrobial resistance (AMR), and climate dynamics poses a critical environmental public health challenge. Freshwater ecosystems are increasingly threatened by the persistent presence antibiotics, which, coupled with rising global temperatures, accelerate development spread AMR. This review examines sources, pathways, mechanisms through which antibiotics enter freshwater systems how change exacerbates these processes. discusses this convergence’s ecological human impacts, highlighting implications for biodiversity health. It also explored current monitoring mitigation strategies, including advanced oxidation processes, natural-based solutions, policy interventions. Finally, identifies research gaps proposes future directions managing intertwined threats resistance, change. emphasizes need integrated, multidisciplinary approaches to protect resources in an volatile environment.

Language: Английский

---

Removal of Ampicillin with Nitrifying Cultures in a SBR Reactor

Applied Biochemistry and Biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 9, 2025

Abstract The presence of antibiotics in wastewater discharges significantly affects the environment, mainly due to generation bacterial populations with multiple antibiotic resistances. cometabolic capacity nitrifying sludge simultaneously remove ammonium (NH 4 + ) and emerging organic contaminants (EOCs), including antibiotics, has been reported. In present study, removal 50 mg ampicillin (AMP)/L by cultures associated biosorption biotransformation processes was evaluated a sequencing batch reactor (SBR) system. contribution enzymes (ammonium monooxygenase (AMO) nitrite oxidoreductase (NOR)) β-lactamases AMP biodegradation using specific inhibitors cultures. 100% eliminated after 5 h since first cycle operation. maintained its oxidizing total consumption 102.0 ± 2.5 NH -N/L 9 h, however, addition altered nitrite-oxidizing process nitrification, recovering 30 cycles later at both physiological kinetic level. activity improved along operating for nitrification processes. elimination 24% attributed 76% biotransformation, wherein AMO enzyme contributed 95% biodegradation. Finally, repeated exposure 72 (36 days) not sufficient detect β-lactamase activity. ability ammonium-oxidizing bacteria biodegrading could be employed bioremediation wastewater. Graphical

Language: Английский

---

Effective removal of tetracycline from wastewater using carbonaceous materials derived from Brassica oleracea plant: Experimental and computational perturbation

Journal of Molecular Liquids, Journal Year: 2025, Volume and Issue: 424, P. 127106 - 127106

Published: Feb. 7, 2025

Language: Английский

---

Construction of binary CuMn2O4/ZnO S-scheme heterostructure photocatalytic system for visible-light-stimulated ciprofloxacin decomposition

Materials Science in Semiconductor Processing, Journal Year: 2025, Volume and Issue: 192, P. 109423 - 109423

Published: Feb. 26, 2025

Language: Английский

---

The Application of Multifunctional Metal–Organic Frameworks for the Detection, Adsorption, and Degradation of Contaminants in an Aquatic Environment

Molecules, Journal Year: 2025, Volume and Issue: 30(6), P. 1336 - 1336

Published: March 17, 2025

Water pollution poses a severe threat to both aquatic ecosystems and human health, highlighting the crucial importance of monitoring regulating its levels in water bodies. In contrast traditional single-treatment approaches, multiple-treatment methods enable simultaneous detection removal pollutants using single material. This innovation not only offers convenience but also fosters more holistic effective approach remediation. Metal–organic frameworks (MOFs) are versatile porous materials that offer significant potential for use wastewater treatment. article examines latest developments application MOFs multifaceted used removal, or degradation contaminants. Some exhibited different functions contaminants, some showed one function (adsorption detection) than contaminant. All multifunctional facilitate multiple treatment real wastewater. Lastly, existing challenges future outlooks concerning MOF addressed this paper.

Language: Английский

---